Physical Education
zohreh mirzavand; mohammad fathi; mostafa bahrami
Abstract
Introduction: Inactivity plays a role in diabetes and increasing tissue oxidative stress and this study aimed to investigate the effect of a period of aerobic exercise on malondialdehyde, superoxide dismutase, and glutathione peroxidase in the heart tissue of male diabetic rats.
Materials and Methods: ...
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Introduction: Inactivity plays a role in diabetes and increasing tissue oxidative stress and this study aimed to investigate the effect of a period of aerobic exercise on malondialdehyde, superoxide dismutase, and glutathione peroxidase in the heart tissue of male diabetic rats.
Materials and Methods: 44 male Wistar rats (200-250 grams) were randomly divided into 4 ten groups of healthy, diabetic, training, and diabetes+ training. After 12 hours of food deprivation, diabetes was induced by intraperitoneal injection of STZ solution, The training groups did aerobic exercise 5 days a week for 6 weeks. 48 hours after completion of the protocol, anesthetized animals and heart tissue were removed. ELISA method was used to measure the amount of superoxide dismutase, malondialdehyde, and glutathione peroxide. Data were analyzed with one-way ANOVA, Tukey's post hoc tests, SPSS, and GraphPad software.
Results: The results showed that superoxide dismutase and glutathione peroxide in the diabetes group were significantly lower than the control, exercise, and diabetes+exercise groups (p≤0.0001). Also, superoxide dismutase and glutathione peroxide were significantly higher in the diabetes+exercise group than in the control and exercise groups (p≤0.0001). Malondialdehyde in the diabetes group was significantly higher than in the diabetes+exercise group, the exercise group, and the control group (p≤0.0001). Malondialdehyde was significantly higher in the diabetes+exercise group than in the diabetes and control groups (p≤0.0001).
Conclusion: aerobic training can have a positive effect on the heart tissue in diabetic rats by reducing oxidative stress.
Psychology
javad taghavi khiabani; FATEME SHAHAMAT DEHSORKH; ATA TEHRANCHI
Abstract
Background: The present study was conducted with the aim of comparing the effectiveness of mindfulness-based therapy and schema therapy on distress tolerance in students with a history of suicide attempts.Materials and Methods: The research method was semi-experimental with a pre-test-post-test design ...
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Background: The present study was conducted with the aim of comparing the effectiveness of mindfulness-based therapy and schema therapy on distress tolerance in students with a history of suicide attempts.Materials and Methods: The research method was semi-experimental with a pre-test-post-test design with two experimental groups and one control group and the statistical population included students had a history of suicide attempts in 1400.With the available sampling method, 45 people were randomly selected and placed in the control group and experimental groups, and all three groups completed the Simmons and Gaher (2005) distress tolerance scale. Then, one of the test groups was exposed to schema therapy and the second test group was subjected to cognitive therapy based on mindfulness. in the end the experimental groups, completed the distress tolerance scale. after one month of the post-test, the follow-up stage was conducted and finally the obtained data were analyzed SPSS.21 software and descriptive statistics indicators and variance analysis of multivariate repeated measures.Results: The results indicated the effectiveness of two interventions on distress tolerance; according to the values of the average score difference in stages of measurement in the groups, the treatment based on mindfulness compared to schema therapy, for the component of regulating efforts to relieve distress and for the other three components, schema therapy is more effective in students with a history of action has committed suicide.Conclusion: The combined use of both treatment methods is suggested to adolescent therapists in increasing the distress tolerance of students with a history of committing suicide.
Physical Education
Fatemeh Akbari Vargsaran; Ameneh Pourrahim Ghoroghchi
Abstract
Introduction: Osteocalcin and osteopontin are related to diabetes and osteoporosis. The aim was to determine the effect of eight weeks of endurance-resistance training and taurine supplementation on osteocalcin and osteopontin in diabetic male Wistar rats.Materials and Methods: In this experimental study,40adult ...
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Introduction: Osteocalcin and osteopontin are related to diabetes and osteoporosis. The aim was to determine the effect of eight weeks of endurance-resistance training and taurine supplementation on osteocalcin and osteopontin in diabetic male Wistar rats.Materials and Methods: In this experimental study,40adult male Wistar rats weighing 250-300grams and 6weeks old were randomly divided into 3 diabetic groups (each group, 10Rat); exercise, supplement and a control and a non-diabetic groups were included as a healthy control group. To make diabetic, 55mg/kg of body weight of streptozocin was injected. Combined exercises were performed for eight weeks and 5times a week. Taurine supplementation was taken as a 1% solution in water daily. One-way ANOVA and Bonferroni's post hoc were used to compare the inter-group and intra-group changes of the variables.Results: Osteocalcin increased significantly in the diabetic exercise group compared to the diabetic control (P=0.018) and decreased significantly in the diabetic control compared to the healthy (P=0.0001). Osteopontin increased significantly in the diabetic control group compared to the healthy control (P=0.003); While, there was no significant difference in other groups (P=1.000). Body weight and BMI increased significantly in the exercise-diabetic group compared to the diabetic-supplement (P=0.0001). There was a significant decrease in food consumption in the diabetic exercise group compared to the diabetic supplement group (P=0.030).Conclusion: Eight weeks of endurance-resistance training and taurine supplementation led to an increase in osteocalcin and no change in osteopontin.
Health Education
parisa Mehrdadian; Salime Golabgirnik; Razieh Khosrorad
Abstract
Introduction: Diabetes is a common disease that leaves serious complications. Educating the patient about the disease and self-care methods can prevent negative consequences, but few patients participate in self-care education. The present study explains the understanding and beliefs of diabetic women ...
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Introduction: Diabetes is a common disease that leaves serious complications. Educating the patient about the disease and self-care methods can prevent negative consequences, but few patients participate in self-care education. The present study explains the understanding and beliefs of diabetic women about the barriers to participating in self-care empowerment programs.Materials and Methods: This qualitative research was conducted in Sabzevar city. Purposive sampling was used to select the participants and theoretical sampling was also used to complete the classes. Data was collected by semi-structured interview. A total of 21 diabetic women were interviewed for 6 months. The interviews were analyzed with Graham and Landman 's content analysis method. To ensure consistency and accuracy of data, credibility, transferability, dependability,and conformability criteria were assessed. Results: The results of the qualitative content analysis led to the extraction of 4 main categories including "scientific information related to the disease and self-care", "the way the doctor deals with the patient and the disease", "the physical and mental health status of the patient" and "beliefs and opinions".Conclusion: According to the findings of the research, it is recommended to design interventions for physicians in order to establish more interaction between physicians and patients, considering the influence of their recommendations and behaviors on patients' decision to participate in self-care and attend educational programs
Physical Education
elahe malekyian fini; Mahbubeh Motefakker; , Sajad Ahmadizad; morteza salimian; fatemeh mokhtari Andani
Abstract
Introduction: Diabetes is one of the most important health problems in the world. The aim of this study was to evaluate the response of a session of resistance exercise with blood flow restriction (REBFR) to hemodynamic and hematological changes in type 2 diabetic patients.Materials and Methods: Fifteen ...
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Introduction: Diabetes is one of the most important health problems in the world. The aim of this study was to evaluate the response of a session of resistance exercise with blood flow restriction (REBFR) to hemodynamic and hematological changes in type 2 diabetic patients.Materials and Methods: Fifteen patients with type 2 diabetes performed knee flexion and extension of the resistance exercise with and without BFR in two sessions with intensity of 20% and 80% 1RM, respectively. Hemodynamic and hematological changes were measured at before, immediately and 30 minutes after exercise. Repeated analysis of variance was used to evaluate the effect of the intervention on quantitative factors.Results: The mean values of systolic and diastolic blood pressure and heart rate values in both training sessions were not significantly different (P <0.05). The results showed that there was no significant difference between WBC, RBC, HCT, Hb, MCH, MCHC, MCV and PV indices between resistance exercise sessions with and without BFR (P <0.05). According to the findings, the amount of RBC and Hb increased significantly immediately after REBFR (P <0.05), which returned to resting levels after 30 minutes of recovery.Conclusion: Low-intensity REBFR due to no significant change in hemodynamic, hematological and platelet parameters can be an effective and low-cost mechanism in preventing cardiovascular disease in patients with type 2 diabetes and as a Non-pharmacological treatment system and alternative to high-intensity resistance exercise to prevent muscle atrophy, especially in clinical populations, especially diabetics.
Aging
Azadeh Hajipour; Maryam Javadi; Mahnaz Abbasi; Isa Mohammadi Zeidi
Volume 28, Issue 6 , January and February 2022, , Pages 923-935
Abstract
Introduction: The present study was conducted to determine the effect of education on glycemic control in the elderly with type 2 diabetes.Methods: The present study was a randomized controlled intervention that was performed on 110 elderly people with type 2 diabetes by multi-stage random sampling method ...
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Introduction: The present study was conducted to determine the effect of education on glycemic control in the elderly with type 2 diabetes.Methods: The present study was a randomized controlled intervention that was performed on 110 elderly people with type 2 diabetes by multi-stage random sampling method in Mallard city (55 in the intervention group and 55 in the control group). The cases received 2 intensive training sessions and then the training follow-up by sending daily SMS to the mobile phone for a period of three months. Data related to demographic status, anthropometric indices, self-care rate and glucose profile indices of patients were collected before and after the intervention. Data were analyzed using SPSS software version 22 and independent t-test, one-way ANOVA and ANOVA.Results: Comparison of glucose profiles of control and intervention patients before and after three months of educational intervention showed a significant decrease in mean FBS and HbA1c (p
Anatomy, Histologyو Embryology
Rahmat allah Fatahian Dehkordi; Kazem Norouzi; Saeed Habibian dehkordi
Volume 28, Issue 1 , January and February 2021, , Pages 30-38
Abstract
Introduction: Diabetes is characterized by high blood glucose levels and defects in insulin production and function. Contamination of food and the environment with lead can worsen the condition of diabetics. This study investigated the effect of thiamine on the small intestinal histomorphology of alloxan-induced ...
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Introduction: Diabetes is characterized by high blood glucose levels and defects in insulin production and function. Contamination of food and the environment with lead can worsen the condition of diabetics. This study investigated the effect of thiamine on the small intestinal histomorphology of alloxan-induced diabetic rats. Material and Methods: In this interventional study, 63 Wistar rats were randomly divided into 9 groups. Three groups of animals were considered as control group (A), thiamine+lead 200 (H) and thiamine+lead 1000 (I). Lead in ppm and acetate form was added to drinking water. The other groups became diabetic via alloxan at a dose of 200 mg/kg. Group B: diabetic mice; Group C: Diabetic mice receiving thiamine; Groups D and E of diabetic mice receiving lead 200 and 1000 were named. Mice in groups F and G received 200 and 1000 ppm of thiamine and lead. Thiamine was used daily and peritoneal with 70 mg/kg dose. On the 29th day, histotechnique was performed on small intestine samples and their histomorphometry was examined. Result: Histomophometry of intestinal structure in mice receiving untreated lead in diabetic group showed a significant increase compared to healthy mice. However, these parameters did not show a significant difference in lead-receiving diabetic rats treated with thiamine compared to the control group. The thiamin improved insulin secretion and reduced turbulence in villi´s of small intestine and improve size of muscular layer in digestive lumen. Conclusion: Probably the antioxidant compound in the thiamin can reduce some complications of lead acetate in diabetic patients.
Foad Alimoradi; Maryam Javadi; Shabnam Jalilolghadr; Anita Avani; Jalal Moludi
Volume 24, Issue 1 , March and April 2017, , Pages 35-41
Abstract
Sleeping is the most important circadian rhythms and one of the fundamental human needs. Approximately, one third of one's life is spent in the sleep. Insufficient sleep has been widespread in the modern society and a large number of people are suffering from it. People with sleep disorders in addition ...
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Sleeping is the most important circadian rhythms and one of the fundamental human needs. Approximately, one third of one's life is spent in the sleep. Insufficient sleep has been widespread in the modern society and a large number of people are suffering from it. People with sleep disorders in addition to fatigue are experiencing the defect in cell regeneration, difficulty in thinking, learning and memory, increased stress and reduced the daily performance on behavior. In most cases, disruption in the sleep cycle is an early symptom in the various diseases. Several studies have shown that the sleep disorders are associated with the incidence and intensifying of diseases, and the improvement of sleep quality in different ages, especially in the adulthood, helps them to avoid the risk of chronic diseases during life. According to evidence and the impressive impact of sleep on health and quality of people’s life and also reducing the quality and quantity of sleep in the modern society, this study examines the importance of sleep and its effect on health, especially the role of sleep in the prevention of metabolic diseases.
Hamid Mohammad Sadeghi; Alireza Vahidi; Mohammad Ebrahim Rezvani; Mansour Esmaeeli Dahej; Ali Aliabadi
Volume 23, Issue 2 , March and April 2016, , Pages 281-289
Abstract
Background: Flavonoids accounted for the most of antidiabetic effects of heral medicines. The effects of Salvigenin, a flavonoids from salvia officinalis, were not reported. We aimed to investigate the effects of the flavonoid on biochemical indices and cardiac hemodynamic parameters of type 1 diabetic ...
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Background: Flavonoids accounted for the most of antidiabetic effects of heral medicines. The effects of Salvigenin, a flavonoids from salvia officinalis, were not reported. We aimed to investigate the effects of the flavonoid on biochemical indices and cardiac hemodynamic parameters of type 1 diabetic rats. Materials and Methods: After extracting the herb, salvigenin was purified by extraction and silica gel column chromatography. Type 1 diabetes was induced by single injection of streptozotocin (STZ) at dose of 70 mg/kg. The rats were allocated into 4 groups as follows: control group that received vehicle and treatments groups that received salvigenin at doses of 5, 10 or 25 mg/kg bodyweight for 30 days. Thereafter, blood samples were collected and fasting blood sugar, hemoglobin A1c, serum lipid profile and serum insulin level were measured. One way analysis of variances was used to assess significant differences between means of parameters between groups. Result: The obtained results implied that salvigenin can significantly reduce fasting blood sugar, hemoglobin A1cand serum lipid profile. In addition, serum insulin level and plasma HDL were significantly elevated in rats treated with salvigenin in compared to control rats.
Seyyed Mohsen Hosseini; Tovhid Jafari Kashki; Masoud Amini; Elham Faghih Imani
Volume 22, Issue 2 , May and June 2015, , Pages 368-376
Abstract
Background: Diabetes mellitus is a metabolic disorder which its subsequent complications such as retinopathy, nephropathy, ulcers, disability, and amputation increase the burden of the disease. Patient-knowledge-improving programs are employed to prevent disease progression and to improve the patients’ ...
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Background: Diabetes mellitus is a metabolic disorder which its subsequent complications such as retinopathy, nephropathy, ulcers, disability, and amputation increase the burden of the disease. Patient-knowledge-improving programs are employed to prevent disease progression and to improve the patients’ quality of life. In this way, we need to characterize the groups of patients with urgent need for more and rich in content programs. In the present study, we used Piecewise regression to evaluate the trends in diabetic nephropathy prevalence among patients registered in Sedigheh-Tahereh Research Center and also identify patients needing more attention.
Materials and Methods: This retrospective study was conducted on 1935 registered patients in the center during 1992-2010.Piecewise regression was fitted using Joinpoint program 3.5.3 to identify change points.
Results: The results showed an upward trend with 2 change points in females (p-value= 0.06). There was 1 change point with an increased trend in recent years in elderly patients, older than 70 years (p-value=0.038).The prevalence of diabetic nephropathy was in rise without any change point among patients with academic education. In addition, patients with family history of diabetes showed the decreased trend with 2 change points (p-value= 0.040). Hypertensive patients experienced a fall in the trend up to 1997 and then this reminded stable.
Conclusion: Evaluating of a disease trend and its complications can lead to developing new theory and innovation. However, this is suggested to conduct further studies to exploring other subgroups and discovering the reasons for increased trend of disease in some subgroups.
Zahra Gorji; Majid Mohammadshahi; Mehdi Zareie; Fatemeh Heidari
Volume 21, Issue 5 , September and October 2014, , Pages 856-869
Abstract
Background and purpose: Diabetes is one of the most common endocrine metabolic disorders, resulting from defects in insulin secretion, insulin action, or both. According to the useful properties of sesame and extensive use of its products (like sesame butter) in Khuzestan province, the purpose of this ...
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Background and purpose: Diabetes is one of the most common endocrine metabolic disorders, resulting from defects in insulin secretion, insulin action, or both. According to the useful properties of sesame and extensive use of its products (like sesame butter) in Khuzestan province, the purpose of this study was to investigate the effects of sesame butter vs. sesame oil on serum glucose levels and lipid profiles on diabetic rats.
Methods: Forty male rats of Wistar Strain were randomly divided into 4 groups (10 rats per group) and were being treated for 6 weeks as follows: Group 1: non diabetic control rats; Group 2: diabetic control rats; Group 3: diabetic rats that were being treated with 1.25 g/kg sesame butter; and Group 4: diabetic rats that were being treated with 0.5 g/kg sesame oil. At the end of the experimental period, serum levels of glucose and lipid profiles were measured. The statistical analysis was carried out, using SPSS 18 software. One way analysis of variance (ANOVA) and Independent sample test were used to compare means between the treated and controlled groups. P< 0.05 was considered as significant.
Results: Utilization of sesame butter and sesame oil in diabetic rats's regime caused a significant decrease in glucose concentrations and also led to increase in high density lipoprotein-c levels compared to the diabetic control rats (P
Mehdi Golafrooz; Hajar Sadeghi; Seyyed Ghasem Mosavi; Yaser Tabarraee
Volume 21, Issue 4 , September and October 2014, , Pages 655-664
Abstract
Background: Research shows that people with diabetes duration less sleep than normal amounts of sleep in healthy people, which may lead to reduced quality of life. Due to the chronic nature of the disease, the need for appropriate follow-up of these patients is necessary. Hence, the present study aimed ...
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Background: Research shows that people with diabetes duration less sleep than normal amounts of sleep in healthy people, which may lead to reduced quality of life. Due to the chronic nature of the disease, the need for appropriate follow-up of these patients is necessary. Hence, the present study aimed to investigate the effect of applying continuous care model on quality of sleep in people with diabetes as well.
Method: In this study, 80 diabetic patients who are candidates for sampling the diabetes clinic covered Sabzevar selected randomly in two groups of test and control. Data were collected using questionnaires, personal information, and Pittsburgh Sleep Quality Scale before and after the intervention. Educational intervention, applying continuous care model in the test group was 12 weeks. Data analysis using descriptive and inferential statistics (chi-square test, t-test, regression and analysis of covariance) was performed by using SPSS version 18.
Results: The results showed that the two groups before the intervention in terms of demographic variables and mean scores of sleep quality, sleep quality scores were similar between the two groups was not statistically significant, However, after intervention by independent t-test, significant differences between the mean scores of sleep quality were (P = 0.001). Between sleep quality scores in the experimental group before and after the intervention, there was a statistically significant difference, but the difference was not significant in the control group.
Conclusions: The implementation of the continuous care model is effective in increasing the quality of sleep. It is suggested by the model to test for diabetes care in other clinics.
Rohollah Safaee pour; Ali Rasouli; Mahmod Parham; Siamak Mohebbi
Volume 21, Issue 3 , July and August 2014, , Pages 473-484
Abstract
Background: Diabetes is considered as one of the most important health issues in 3rd millenary that the number of the patients is increasing. Self-care has been known as one of the most effective method for The prevention and control of diabetes complications. This research was performed to assess the ...
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Background: Diabetes is considered as one of the most important health issues in 3rd millenary that the number of the patients is increasing. Self-care has been known as one of the most effective method for The prevention and control of diabetes complications. This research was performed to assess the self-caring grades in diabetic patients who come to Qom diabetes community in 1391.
Materials and Methods: this cross-sectional descriptive and analytic study was conducted on 251 diabetic patients referring to the Qom diabetes community and was selected randomly. Demographic and information record checklist and also standard SDSCA questionnaire were used to collect data. Obtained information was analyzed through SPSS software 18 and p value lower than 0.05 was considered as significant level.
Results: Results showed a proportion of 32.99% have never performed any self-caring activity and only 7.97% of them followed these every day. The mean values of FBS and HbA1c were 157.74 mg/dl and 7.74 mg/dl, respectively and also self-caring score was 46.53. There was observed a significant reverse association between FBS and HbA1c values.
Conclusion: Self-caring is substantially unacceptable in diabetic patients who are under covered of Qom diabetes community and they don’t perform some self-caring actions like diary regime, appropriate exercise, control of blood glucose, foot caring and also taking medicine or insulin injection completely and regular. For this reason, these patients had inappropriate values of FBS and HbA1c
Javad Behrozi; Adeleh Divsalar; Ali Akbar Sabouri
Volume 21, Issue 3 , July and August 2014, , Pages 482-492
Abstract
Background: Diabetes is one of the most common endocrine disorders. In this disease due to increased blood glucose levels, protein glycation increases. Protein glycation in diabetes leads to irreparable consequences. The aim of this study was to investigate the synergic effect of Bee venom and aspirin ...
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Background: Diabetes is one of the most common endocrine disorders. In this disease due to increased blood glucose levels, protein glycation increases. Protein glycation in diabetes leads to irreparable consequences. The aim of this study was to investigate the synergic effect of Bee venom and aspirin on human hemoglobin glycation in the presence of glucose.
Materials and Methods: In this experimental study, hemoglobin (10 mg/ml) was incubated in the presence and absence of glucose (40 mM), aspirin (2.5 mM) and Bee venom (in different concentrations of 10, 20 and 40 µg/ml) for 5 weeks. Amount of hemoglobin glycation was evaluated via investigation of changes in soret band, amount of hemoglobin heme degradation and alteration in secondary structure of protein using UV-visible spectroscopy, fluorometry and Circular Dichroism Spectropolarimetry methods. The data were analyzed using InStat 3 software and statistical tests including one way variance analysis and Tukey test. P values less than 0.05 were considered significant.
Results: Hemoglobin incubation in the presence of glucose led to reduction of soret band absorption, degradation of heme and increment of beta sheet value in secondary structure of hemoglobin. Simultaneous presence of Bee venom and aspirin reduced the rate of heme degradation (p< 0.001) up to 36%, and the beta sheet formation up to 54% (p< 0.001). Also, the amount of structural alteration and hemoglobin glycation significantly decreased.
Conclusion: Bee venom and aspirin have significant antiglycation properties and simultaneous use of them can decrease protein glycation.
Ali Heidarianpour; Ebrahim Zarrin kalam
Volume 20, Issue 1 , March and April 2013, , Pages 34-41
Abstract
Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this ...
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Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this study is effects of resistance exercise on vascular function of C-peptide. Materials and methods: In this experimental study, Male wistar rats (220±10g, N=30) were used in two diabetic (control and trained) and one age-matched healthy control groups. After 1 week of diabetes induction, animals were submitted to resistance exercise training for 9
Weeks on ladder. To characterize cutaneous micro vascular responses by Laser Doppler
flowmetery, animals were deeply anesthetized by intraperitoneal injection of pentobarbital
sodium (50 mg/kg). For data analysis, one-way ANOVA test was used to compare the groups. Statistically significant difference between the minimum acceptable levels is p<0.05
Results: Local microinjection of c-peptide increased coetaneous blood flow in trained and control diabetic rats, however this effect in trained group is higher than control diabetic group rats. Administration of Nw-nitro-L-arginine (nitric oxide synthase inhibitor) before C-peptide reduced significantly C-peptide vascular effects in trained and control diabetic rats. Conclusions: Chronic resistance exercise potentiate C-peptide vascular function, possibly by nitric oxide pathway
Ali Kheradmand; Akbar Ranjbarzade; Kazem hassanpour; Fatemeh Bidi
Volume 19, Issue 4 , January and February 2013, , Pages 336-344
Abstract
Background: Diabetes is the most widely and important patient that derived from body metabolism disorders. Health education and modification and behavioral methods are more effective and economic way to prevent and control the diabetes. So, the aim of present research is study of the effect of changing ...
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Background: Diabetes is the most widely and important patient that derived from body metabolism disorders. Health education and modification and behavioral methods are more effective and economic way to prevent and control the diabetes. So, the aim of present research is study of the effect of changing behavior on knowledge, attitudes, self-care, quality of life, and lifestyle of type II diabetic patients. Materials and Methods: Research method was experimental that carried out using the pretest–posttest plan and a control group. From patients with type II diabetes who referenced to Bojnord health center selected forty patients that fitted to identified criteria and assigned to 2 group of experiment (20 patients) and control (20 patients). Five-section questionnaire was implemented to determine the demographic information and to measure knowledge (from Ghanzanfari and reliability 0.84), attitude (from Ghanzanfari and reliability 0.81), self-care (from Ghanzanfari and reliability 0.91) and quality of life (SF-20 and reliability 0.79). These tools conducted in 2 stages. Validity of questionnaires has approved through experts. Educational program based on modification of habits and nutrition method conducted in 5 session 30 minutes. Data analyzed through SPSS 18. Results: The mean age of people was 52.17±7.58. The results showed that intervention of education had no significant effect on the knowledge of the people under study (p=0.083). However, on the variables of attitudes toward the illness (p=0.001), self-care (p=0.001) and quality of life (p=0.001), intervention of changing behavior had a significant effect. Conclusion: Implementing health care and changing inappropriate behaviors, type II diabetic patients would be able to change their attitude toward life and lifestyle. Such cares would be better to be continuous and the clinical and psychological methods to be applied in addition to the pharmaceutical ones.
Marziyeh Vaezy; HamidReza Aghamohamadian; Bahram Ali Ghanbari
Volume 17, Issue 1 , March and April 2010, , Pages 27-32
Abstract
Background and Purpose: The effect of stress on diabetes is a complex issue but its relationship with blood sugar level and diabetes control has been clarified. The present study was carried out to compare the stressor and coping strategies in subjects with diabetes and normal subjects. Methods and Materials: ...
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Background and Purpose: The effect of stress on diabetes is a complex issue but its relationship with blood sugar level and diabetes control has been clarified. The present study was carried out to compare the stressor and coping strategies in subjects with diabetes and normal subjects. Methods and Materials: This case-control study was conducted on diabetic and normal subjects, including 30 subjects with diabetes and 30 normal subjects. Research instruments were daily stressors assessment questionnaire and the ways of coping with stress questionnaire. Independent t-test in SPSS was used for testing the hypotheses. The validity and reliability of the questionnaire were 0.88 and 0.84 respectively. Results: There was a significant difference between frequency of stressors in subjects with diabetes (mean 307.33) compared to normal subjects (mean 173.2) (p
Mahnaz Azadi Moghtader; Ali Heidaryanpour; Efat Sadeghian
Volume 15, Issue 4 , January and February 2009, , Pages 200-206
Abstract
Background and Purpose: Magnesium deficiency has recently been proposed as a novel factor implicated in the pathogenesis of diabetes complications such as vascular disorders but the mechanism has not been completely clarified. The present study was designed to determine the effect of oral magnesium sulfate ...
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Background and Purpose: Magnesium deficiency has recently been proposed as a novel factor implicated in the pathogenesis of diabetes complications such as vascular disorders but the mechanism has not been completely clarified. The present study was designed to determine the effect of oral magnesium sulfate administration on skin microvascular blood flow in diabetic rats. Methods and Materials: In this experimental study 50 male Wister rats (200–250 g) were divided into two diabetic and one control groups. One diabetic group received magnesium sulfate (10 g/L) in drinking water for a 10-week period. The other two groups received only tap water. After 10 weeks animals were deeply anaesthetized and placed on a heating pad to maintain their body temperature at 37±0.5°C. Laser Doppler flow meter was used to measure the relative changes in skin blood flow. After stabilization we used ACh SNP L-NNA+ magnesium sulfate (0.1M) in control and experimental animal by microsyringe pump microinjection. In order to analyze the obtained data Student t-test and One-way ANOVA were used in SPSS with p
Alireza Abadi; farideh Tahbaz; MohammadHasan Entezari; Hamidreza Shams
Volume 15, Issue 2 , July and August 2008, , Pages 98-103
Abstract
Background and purpose: Researchers have Recently Recommended high-fiber and low glycemic-index foods for glycemic control in diabetics and reduction of Lipid Profiles. This Study intended to investigate the effect of baked lentils ( as a highly consumed and low glycemic index) on FBS and Lipid Profiles ...
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Background and purpose: Researchers have Recently Recommended high-fiber and low glycemic-index foods for glycemic control in diabetics and reduction of Lipid Profiles. This Study intended to investigate the effect of baked lentils ( as a highly consumed and low glycemic index) on FBS and Lipid Profiles in type II diabetics. Methods and materials: This cross-over clinical trial was conducted on 30 type II diabetic patients of 45- 60 years (divided randomly into two groups of 15) with FBS of 126-180 mg/dl. The control group was given the usual diet but the experimental group received 50 gr baked lentild 6gr canola oil instead of (30 gr) bread and 20 gr cheese (in the form of an isocaloric breakfast with similar amounts of macronutrients). For 6 weeks after a 3- week rest subjects in the two groups were interchanged. Diets were switched between the two groups and continued for another 6-week Period. At the beginning and end of each phase of the study biochemical and anthropometric measurements were recorded. Calculations of dietary components were done using Food Processor II and the data were analyzed using t-test in SPSS. Results: Fasting blood glucose of the patients decreased significantly from 152.6±11.4 mg/dl to 148.4±11.8 mg/dl (p
MH FOROUZANFAR; S HOSSEINI; M BAHRAMI; A ATAEI JAFARI; B ALI REZAPOUR; M PAJOUHI
Volume 14, Issue 4 , January and February 2008, , Pages 211-217
Abstract
Background and Purpose: Sweeteners make the diet more palatable. Honey is a natural sweetener which can be useful in weight loss due to its antioxidant content. In this study, we examined the effect of honey intake on body weight and blood glucose of overweight and obese subjects with type 2 diabetes.
Methods ...
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Background and Purpose: Sweeteners make the diet more palatable. Honey is a natural sweetener which can be useful in weight loss due to its antioxidant content. In this study, we examined the effect of honey intake on body weight and blood glucose of overweight and obese subjects with type 2 diabetes.
Methods and Materials: This randomized clinical trial was conducted on 34 type diabetics with BMI³25 kg/m2 and fasting blood sugar (FBS) 110-220 mg/dl. Exclusion criteria were malignant disease, major surgery, taking immunoregulatory, cytotoxic or immunosuppressive drugs, pregnancy or lactation in women and insulin injection. They were randomly assigned into 2 groups: Honey Group received oral natural honey for 8 weeks, but the control group continued their usual diet. Body weight and FBS measurements were done at the end of weeks 0, 2, 4, 6 and 8. Repeated measurement analysis was used for analyzing the trend of changes.
Results: After the adjustment for the baseline values, the amount of weight loss in the Honey group was 1.6±0.33 kg in average less than the control group (P=0.0001). After the adjustment of the effect of the baseline FBS, the trend of FBS changes were 10.38±8 mg more than the Honey group, which was not significant. The FBS changes were not also significant across the two groups.
Conclusion: The 8-week consumption of honey can help lose body weight in obese and overweight diabetic patients without any harmful damages on blood glucose.
SH JAMSHIDI; B FARAHMAND; A AKBARZADEH; B ,LAMEH RAD
Volume 12, Issue 4 , January and February 2006, , Pages 6-13
Abstract
Background and Purpose: Although it is now certain that insulin injection allows us to control the complications resulting from blood sugar imbalances, its accurate control by insulin injection is difficult. Therefore as a logical solution, transplantation of islet cells is globally considered as a treatment ...
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Background and Purpose: Although it is now certain that insulin injection allows us to control the complications resulting from blood sugar imbalances, its accurate control by insulin injection is difficult. Therefore as a logical solution, transplantation of islet cells is globally considered as a treatment and the present study is conducted to verify it.
Methods and Materials: After materials preparation, donor tissue was obtained from 6 male wistar rate cage 75-90 days (weight 250-300 gram). Transplantation was done on diabetic rate induced 2-4 weeks earlier by 60 mg/kg streptozotocin intravenous injection.
Results: After islet cells transplantation, blood glucose was reduced to normal (145±5 mg/dl) and insulin and C-peptide increased (1.9±0.1 MIU/L and 0.053±0.001 mg/ml respectively). Clinical symptoms of dibetes induction were relieved after transplantation.
Conclusion: The technique of islet cells transplantation in the form of encapsulation with the absence of immunological inhibitors to support the graft against the recipient's immunity system is an innovative method to treat type I diabetes.