Yaser Nozohor; Mohammad hasan Rasouli fard; Jafar Rahmani; Payam Faramarzi
Volume 25, Issue 2 , May and June 2018, , Pages 303-309
Abstract
Introduction: Urinary tract infection is one of the most common infections and the second cause of infection in human body. The main cause of this infection is gram negative bacteria such as E coli. The base of treatment for urinary tract infection is administrating an appropriate antibiotic. Today, ...
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Introduction: Urinary tract infection is one of the most common infections and the second cause of infection in human body. The main cause of this infection is gram negative bacteria such as E coli. The base of treatment for urinary tract infection is administrating an appropriate antibiotic. Today, antibiotic resistance is considered as an important challenge in treating infections. High and unnecessary use of antibiotics especially in urinary infections resulted in resistance to some antibioticsThis study aimed to evaluate the antibacterial effect of alcoholic extract of Escherichia coli took over the pine leaves.Methods: In this experimental study the Alcoholic extract was extracted using. its antimicrobial activity agar disk diffusion method for determination of bacterial sensitivity and dilution method for determination of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) is used separately.Results: Also the results of MIC and MBC tests indicated that the inhibition of E.coli and Staphilococci aureus bacterial growth by Alcoholic extract of pine had a direct relationship with the amount of available alcoholic extract of pine. with increasing of Alcoholic extract of pine in each dilution, reduced the number of cultured bacterial colonies and no bacterial growth was observed in the dilution equivalent to MBC of Alcoholic extract of pine.Conclusion: The results suggest that Alcoholic extract of pine can be used as a source of cheap and accessible replacing chemical drugs to treat some bacterial infections.
Ali Heidarian pour; Fatemeh Zamiri Dalir; Mohammad Shorideh Yazdi
Volume 23, Issue 2 , March and April 2016, , Pages 336-343
Abstract
Background & Objectives: According to benefits of psycho-physiological effects of aerobic exercise, the purpose of this study was to investigate the effects of eight-week moderate-intensity aerobic exercise training on menstrual cycle disorders and plasma levels of FSH and LH. Methods: In this ...
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Background & Objectives: According to benefits of psycho-physiological effects of aerobic exercise, the purpose of this study was to investigate the effects of eight-week moderate-intensity aerobic exercise training on menstrual cycle disorders and plasma levels of FSH and LH. Methods: In this study, 20 women with menstrual disorder randomly divided into two experimental and control groups. The experimental group submitted 8 weeks of moderate-intensity aerobic exercise, while the control group had no regular physical training. 24 hours before and after the period of exercise training, follicular phase blood samples of all subjects were taken to measure hormonal variables and then they responded to questionnaires to determine levels of menstrual disorders. Results: The research results revealed that, after 8-week training, pain at Visual Analgesic Scale in experimental group decreased significantly (p<0.05). In addition, plasma level of FSH and LH hormones significantly increased and decreased respectively (p<0.05). Conclusion: It can be concluded that, by regular endurance exercise of moderate intensity, Dysmenorrheal can be reduced, and these exercises can be used as a preventive treatment or therapy to help control Dysmenorrhea and menstrual disorders.
Psychology
mohammad ebrahimzadeh mousavi; Sara Aminoroaya
Volume 25, Issue 3 , July and August 2018, , Pages 389-398
Abstract
Background and Objectives:Eating Disorder is one of the common psychiatric disorders that is associated with severe psychiatric illnesses. These types of disorders can cause problems in physical and psychological well-being. The purpose of this study was to investigate the association between eating ...
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Background and Objectives:Eating Disorder is one of the common psychiatric disorders that is associated with severe psychiatric illnesses. These types of disorders can cause problems in physical and psychological well-being. The purpose of this study was to investigate the association between eating disorders and body dysmorphic disorders and their correlation with psychopathology syndrome.Methods: This research is a causal-comparative study. The population of the study consisted of high school students in district 5 of Tehran, which was selected by stratified random sampling method and based on the sample size of Cochran samples, 400 individuals were selected as samples in 1395. The data collection tool was (YBOCS-BDD), (EAT-26), and (BSI). Data analysis was done at descriptive and inferential levels (Pearson correlation, t-test and regression) using SPSS-22 softwareResults: 67.6% of participating girls and 0.55% of participating boys had pathological disorders of eating disorder. In addition, 0.70% of the girls and 0.37% of the boys had a body dysmorphic disorder. The correlation between eating disorder and body dysmorphic disorder was 51% which was significant at the level (p
Psychology
Farangis Demehri; Sama Meghdadi; Mohsen Saeedmanesh
Volume 27, Issue 3 , September and October 2020, , Pages 431-439
Abstract
Introduction: Epilepcy is a chronic and neurological disease. The aim of this study was to determain the effectiveness of computer gamesbased on visual skills on visual perception and concentration of children with epilepsy disorder.
Materials and Methods: This is a quasi-experimental study with ...
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Introduction: Epilepcy is a chronic and neurological disease. The aim of this study was to determain the effectiveness of computer gamesbased on visual skills on visual perception and concentration of children with epilepsy disorder.
Materials and Methods: This is a quasi-experimental study with pretest and post-test design with control group. The statistical population of this study was all children with epilepsy disorders referring to the epilepsy disorder treatment center in Mashhad. The sample was 30 these individuals have been selected and voluntarily selected according to the criteria and randomly divided into two experimental and control groups. The tools used in this research were the computer focus test (COG) (2012) and the Frostheit Visual Perception Test (1982). Finally, the data were analyzed by descriptive and inferential statistics using covariance analysis. For this purpose, SPSS-24 software was used.
Results: The results showed that there was a significant difference between the mean post-test scores of visual perception (P <0.01) and concentration (P0.05) after elimination of pre-test. The mean score of the post-test group was significantly more than the control group, which meant that the use of computer games in visual skills increased visual perception and concentration.
Conclusion: The results showed that the use of computer games in visual skills increased visual perception, and concentration on the experimental group in the post-test phase, compared with the control group.
Psychology
ali sedaghati rad; Mohammad Mohammadipoor; Aliasghar Saraei
Volume 28, Issue 3 , May and June 2021, , Pages 439-447
Abstract
Introduction: Considering the harmful and irreparable effects of addiction to prevent serious harm to students, it seems that measures should be taken in this regard. The aim of this study was to compare the effectiveness of group schema therapy and planned behavior training on student addiction of teachers ...
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Introduction: Considering the harmful and irreparable effects of addiction to prevent serious harm to students, it seems that measures should be taken in this regard. The aim of this study was to compare the effectiveness of group schema therapy and planned behavior training on student addiction of teachers at Farhangian University of Mashhad. Materials and Methods: The design of the present study is quasi-experimental in three groups with pre-test and post-test. The study population was all student teachers in the campuses of Khorasan Razavi province in the academic year of 2019-2020. Forty-five student-teachers were randomly assigned to three groups: schema therapy (n=15), planned behavior training (n=15), and control (n=15). The intervention groups underwent 11 sessions of 60-minute schema therapy and 8 sessions of 90-minute planned behavior training, respectively, and the control group did not receive treatment. Data by scale Goldsmith Addiction (2006) It was collected during three stages and analyzed by repeated measures analysis of variance. Results: The research findings showed that group schema therapy and planned behavior training are effective in reducing student-teacher addiction . This effect after one month follow-up in both groups was durable (P <0.01). There was also a significant difference between the two interventions (p < 0.01). Conclusion: Both schema therapy and planned behavior training can be effective in preventing youth addiction.
Nahid Jesri; Abedin Saghafipour; Fatemeh Rezaei; Moharram Karami Jooshin
Volume 23, Issue 3 , July and August 2016, , Pages 496-503
Abstract
Background This study aimed to assess the geographical distribution of smoking which is a risk factor for non-communicable diseases such as cancer, cardiovascular disease, and respiratory disorders in Iran. In this regard, mapping of cigarette smoking was designed and implemented using Geographic Information ...
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Background This study aimed to assess the geographical distribution of smoking which is a risk factor for non-communicable diseases such as cancer, cardiovascular disease, and respiratory disorders in Iran. In this regard, mapping of cigarette smoking was designed and implemented using Geographic Information System.Materials & Methods This is a cross-sectional study. Initially, the national data from risk factors for non-communicable diseases screening program were collected from the Iranian Non-communicable Disease Control Center. Then, the incidence of cigarette smoking in each province was calculated. These data have been prepared by the Health Ministry. In the next step, the data were analyzed using descriptive statistics. Then, these data were arranged in a geo-referenced database in the ArcGIS software. The map of distribution of cigarette smoking was drawn by ArcGIS version 9.3.Results The incidence of cigarette smoking in Iran has been estimated as 10.82%. More than 20% of Iranian men currently smoke tobacco on a daily basis and this percentage among Iranian women is 1.02%. The average start age of smoking is at the age of 20.13 years. The average smoking years was 13.82 years. Cigarette smoking in many provinces, such as Tehran, West Azerbaijan, Ardebil, as well as Chaharmahal and Bakhtiari, were higher than the national average. Conclusion People in the provinces of Tehran, West Azerbaijan, Ardebil, as well as Chaharmahal and Bakhtiari, are more exposed to the danger of cigarette smoking than the people in the other provinces.
Zahra Poshtchaman; Maryam Jadid Milani; Forozan Atashzadeh Shorideh; Alireza Akbarzadeh Baghban
Volume 22, Issue 4 , September and October 2015, , Pages 668-675
Abstract
Background and aims: The increasing of heart disease, high rate of hospitalization due to the disease and also the high cost of treatment and care, has caused that important challenge facing the health system in the present century. Therefore, heart disease prevention and successful treatment is essential ...
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Background and aims: The increasing of heart disease, high rate of hospitalization due to the disease and also the high cost of treatment and care, has caused that important challenge facing the health system in the present century. Therefore, heart disease prevention and successful treatment is essential This is possible only with the patients’ active involvement in treatment and to implement the recommendations of the health care team which this is mentioned as treatment adherence. The present study conducted to determine the status of treatment adherence in patients after coronary artery bypass graft in Tehran in 2014 Material and Methods: This cross-sectional study was conducted on 70 patients undergoing coronary artery bypass graft in Tehran. Needed data were collected via demographic checklist and treatment adherence questionnaire that were completed by patients in five days after coronary artery bypass surgery and before discharge. For data analysis, descriptive statistics, Pearson coloration and Chi square were used. Results: The mean score of treatment adherence was 59.36± 8.08. Among subscales, maximum score was for Combining treatment with life (68/06± 19/34) and minimum score was dedicated to planning in performance of treatment (44.52± 25.62). There was a significant correlation between all subscales of treatment adherence instrument (p=0/0001) except for concern to treatment and planning in performance of treatment and also participate in treatment with commitment to treatment that there was observed no significant relationship. Conclusion: The results showed that Treatment coordination with living conditions and social support from family and friends is associated with better adherence in patients undergoing coronary artery bypass graft. There is suggested that adherence to treatment consider as an educational program in nursing care of these patients.
Sohrab Golmohammadi; Abdol Azim Alinejad; Afshin Ghaderpoury; Nezam Mirzaei; Mohammad Hossien Saghi; Mansour Ghaderpoori
Volume 23, Issue 4 , September and October 2016, , Pages 680-687
Abstract
Background Wastewater from textile dyes, which contain organic pollutants, is a major source of environmental contamination. This study aimed to determine the efficiency of the photo-catalytic process of ZnO nanoparticles in removing Acid Black 1 from aqueous solutions.Methods & Materials This study ...
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Background Wastewater from textile dyes, which contain organic pollutants, is a major source of environmental contamination. This study aimed to determine the efficiency of the photo-catalytic process of ZnO nanoparticles in removing Acid Black 1 from aqueous solutions.Methods & Materials This study was quasi-experimental. The nanoparticles were synthesized in the laboratory. To determine their characteristics some tests, including SEM, XRD and particle size distribution were done. The optimum pH was determined in the test, then, by maintaining the optimum pH, hydrogen peroxide concentration, dye concentration and different concentrations of nanoparticles were studied.Results The results showed that the removal efficiency of this process is maximum at pH=4 and equals to 1.15%. The best color removal efficiency was obtained at a concentration of 5 mg/l. The maximum and minimum removal efficiency as a color block acid were obtained at a concentration of 30 and 5 Mmol/mL of hydrogen peroxide, respectively.Conclusion Nano-photo catalytic process is a highly efficient method for the removal of dyes in aqueous solutions. In this process, organic materials are converted into less toxic substances also the energy of sunlight, which is used in this process is normally available
Psychology
Sajjad Basharpoor; nesa kazemi; Mohammadnabi salehi
Volume 25, Issue 5 , November and December 2018, , Pages 731-739
Abstract
Aim: Breast cancer is the most effective emotional and psychological cancer among women, which causes deep emotional and emotional problems in the patient, considering that death anxiety is one of the important psychological variables in cancer patients and self-differentiation level with person's ability ...
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Aim: Breast cancer is the most effective emotional and psychological cancer among women, which causes deep emotional and emotional problems in the patient, considering that death anxiety is one of the important psychological variables in cancer patients and self-differentiation level with person's ability To reduce anxiety. Therefore, the aim of this study was to evaluate the effectiveness of positive group psychotherapy on self-differentiation and death anxiety in women with breast cancer in Bijar city.Materials and Methods: The method Current study was Experimental to pretest-posttest design with control group. A sample was selected from all women with breast cancer, whose names were recorded in Bijar Health Center until 2013. people 30 Based on criteria for having a history of breast cancer and diagnosis by a specialist, having read and write literacy, being married, were selected. They were randomly divided into experimental and control groups. The instrument used in this study was a standard self-differentiation questionnaire (DSI-R), Death Anxiety Scale (DAS), and a positive group psychotherapy package. The datas were analyzed by SPSS-21 software and descriptive indicators and covariance analysis test. Results: The results of covariance analysis indicated that there was a significant difference between the post-test of two groups in self-differentiation (P< 0.000, F=38/58) and death anxiety (p
Microbiology
Zohreh Ahmadiyan fard; Amin Moazami
Volume 26, Issue 6 , March and April 2020, , Pages 789-795
Abstract
Background and Objectives: Ureaplasma urealyticum and Mycoplasma genitalium are the most important opportunistic pathogens in the female reproductive system and the causative agent of the pelvic infection, non-gonococcal urethritis, abortion and infertility. The aim of this study was to frequency of ...
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Background and Objectives: Ureaplasma urealyticum and Mycoplasma genitalium are the most important opportunistic pathogens in the female reproductive system and the causative agent of the pelvic infection, non-gonococcal urethritis, abortion and infertility. The aim of this study was to frequency of Mycoplasma genitalium and Ureaplasma urealyticum among infertile women with vaginal infection by PCR in Kerman. Materials and Methods: In this cross-sectional study, the endo cervical swab sample from 60 women with vaginal infection (vaginitis and cervicitis) referred to the diagnostic laboratories of infertility treatment centers in Kerman in 2013 was prepared. The specimens were transferred to the laboratory in the transport medium and the DNA extracted from the specimens was analyzed as a template for amplification of the 16S rRNA encoding gene in the PCR reaction. Data were analyzed by SPSS V.21 software.Results: Among 60 samples, 38% (23sample) of the samples had mycoplasma contamination and Ureaplasma urealyticum and Mycoplasma genitalium bacteria were found in 13.32% (8 sample) and 11.6% (7 sample) of patients, respectively.Conclusion: Considering the potential effects of mycoplasmas on the complications of infection in maternal pregnancies and infant mortality, Therefore, the need for rapid diagnosis of this infection is felt more than ever. From the two microbial agents studied in this study, the possibility of infertility caused by infection with Ureaplasma urealyticum increased significantly, but more studies are needed
Gholamreza Godarzi; Kambiz Ahmadi Angali; Javad Salimi; Farrokh Ghaffarizadeh; Farzad Kadkhodaee; Gholamreza Ebrahimzadeh; Ameneh Eskandari; Fatemeh Barjasteh Askari
Volume 22, Issue 5 , November and December 2015, , Pages 832-841
Abstract
Backgrounds: Today, the different consequences of air pollution especially on health effects caused to evaluate, monitor and control air quality as the most important national issues. The aim of this study was to determine the health quality of air in Zabol city based on AQI index and mortality rate ...
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Backgrounds: Today, the different consequences of air pollution especially on health effects caused to evaluate, monitor and control air quality as the most important national issues. The aim of this study was to determine the health quality of air in Zabol city based on AQI index and mortality rate caused by dust.
Materials and Methods: This is a descriptive-cross sectional study. The concentration of air pollutants, including carbon monoxide, sulfur dioxide, nitrogen dioxide, suspended particles were measured by Zabol environmental department using BAM 1020 device in 2011.Air quality index was calculated by interpolation between four concentrations of criteria pollutants. In addition, AirQ2.2.3 computer model was used to determine the mortality rate caused by dust.
Results: The results showed that air qualities in 68 percent of the days were exceeded from standard limit in 2011. According to AQI index, the air qualities in 27% and 6% of days in Zabol city were classified into unhealthy and very unhealthy categories, respectively. PM10 as pollutant was responsible for the pollutant of Zabol city. Furthermore, the number of admission rate in hospitals were 575, respiratory diseases 41 and cardiovascular diseases 227.
Conclusions: A survey on air quality index (AQI) in July, August and September showed that the highest level of PM10 which classified in "very hazardous" (401 <AQI <500) category which was related to a hundred and twenty days winds of Sistan. Although in Zabol city, there are not problems of big cities such as industries and traffic jam, but due to number one in the occurrence and severity of storms in the country and experiencing 107 days in very dangerous condition and regarding to high number of deaths caused by exposure to dust, required special attentions to improve environmental conditions, proper planning and reducing exposure of sensitive groups in dusty days.
Anatomy, Histologyو Embryology
Behrooz Yahyaei; Mahnaz Nouri; Maedeh Ramezani
Volume 25, Issue 6 , November and December 2018, , Pages 885-894
Abstract
Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice ...
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Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice Wistar rat. 49 rats into 7 groups: control (n=7), sham (n=7), no practice at a dose of 2mg/kg Boldenone (n=7), without practicing at a dose of 5mg/kg Boldenone (n=7), group exercise (n=7), a workout at a dose of 2mg / kg dose Boldenone (n=7) and practice 5mg/kg Boldenone (n=7) were divided. The mice were kept under identical conditions and with the same power and endurance activities according to their protocol and drug Boldenone the intervention groups were injected. After eight weeks, the mice were anesthetized and sacrificed them tissue samples from the cerebellum were prepared.Results: There was a significant difference between the groups treated with exercise and control group without exercise. In the group exercise amount and rate of change of the cerebellum tissue is significantly lower than the control group. And even there was a significant difference between the two groups with different dosages also under endurance exercise.Conclusion: The results showed that endurance and aerobic activity for 8 weeks can be largely Boldenone effects of the drug on mice reduces brain tissue but with increasing doses Boldenone creation these changes are inevitable.
Hasan Bagherinia; Mohammad Yamini; Es-hagh Ilderabadi; Fahimeh Bagherinia
Volume 22, Issue 6 , January and February 2016, , Pages 1063-1070
Abstract
Background and aim: Nurses encounter with different job stresses that because of different personality traits meet stress in different ways and their mental health affected by personality traits. The aim of this research is investigation of relationship between personality traits and mental health with ...
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Background and aim: Nurses encounter with different job stresses that because of different personality traits meet stress in different ways and their mental health affected by personality traits. The aim of this research is investigation of relationship between personality traits and mental health with resilience mediation in nurses.
Methods and Materials: This research is descriptive with path analysis way. 105 nurses in Sfarayen hospital were randomly selected. NEO personality, Conner and Davisson and Goldberg mental health questionnaires were used. Correlation and path analysis tests using SPSS and AMOS for data analysis.
Results: Results indicated that direct effects of neuroticism (Beta= 0/282 and P=0/000), consciousness (Beta=0/207 and P=0/002), and resilience (Beta=0/392 and P=0/000) are significant on mental health and other direct paths into mental health were not significant and also personality traits of neuroticism (Beta= -0/236 and P=0/000), agreeableness (Beta=0/147 P=0/000), and openness (Beta= 0/044 and P=0/014) have indirect significant effect.
Conclusion: Personality traits in addition to direct effect on mental health have indirect effect on mental health via resilience. So it can mention resilience variable as one mediator variable between personality traits and mental health.
Nursing
akram Shamsabadi; mehdi jafarzade fakhar; Mohammad Hasan Rakhshani; aliakbar jannatabadi
Volume 25, Issue 1 , May and June 2018, , Pages 135-142
Abstract
Background: Administration of medications is an important part of treatment and care provided by nurses. Medication errors in nursing profession is one of the most common health care mistakes.One of the factors in the incidence of medication errors, job stress, so stress management and efficient use ...
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Background: Administration of medications is an important part of treatment and care provided by nurses. Medication errors in nursing profession is one of the most common health care mistakes.One of the factors in the incidence of medication errors, job stress, so stress management and efficient use of preventive methods necessary to appear. The aim of this study is to determine the effect of a Stress Inoculation training on the medication error of nurses. Materials and methods: The present research is, a field trial controlled study.The population included 100 nurses in medical, surgical and pediatric hospitals constitute Sabzevar University of Medical Sciences. Nurses are selected using quota sampling permutation blocks were divided into two groups.The intervention group, stress inoculation training (workshop 2 days 8 hours a week) was conducted.The data collecting by a researcher-made forms of occupational demographic information and registration forms medication errors,during the two stage, one months before and one and a half months after the intervention was completed by both groups. Data were analyzed by means of SPSS-11/5 and SAS 9.1 statistical software using descriptive statistics, Mann-Whitney, Chi-square, Fisher, T test and generalized estimation equations. Results:The mean and standard deviation of medication errors in the intervention group before stress inoculation training 5/65 ± 2/30 and a half months was 2/68 ± 1/57. Analysis of data between the mean medication errors samples before and after the intervention groups showed significant differences (P<0/05). Conclusion:Stress inoculation training can reduce the incidence of medication errors.
Fatemeh Poramirrzdari; Parviz Karimi Sani
Volume 23, Issue 1 , May and June 2016, , Pages 143-150
Abstract
Background & Objectives:Considering the importance of poetry in reducing stress, the aim of this study was to evaluating the use of poetry to reduce irrational beliefs in female students. Materials & methods: The research design was quasi-experimental, pretest-posttest with control group. The ...
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Background & Objectives:Considering the importance of poetry in reducing stress, the aim of this study was to evaluating the use of poetry to reduce irrational beliefs in female students. Materials & methods: The research design was quasi-experimental, pretest-posttest with control group. The research population included all secondary school female students in Urmia in the 2013-2014 school years. The sampling method was multi-stage cluster. The random sample of 30 students who have high scores on the questionnaire irrational beliefs were selected randomly in two experimental and control group and Poetry therapy sessions were conducted on the experimental group and irrational beliefs questionnaire Jones was administered on them. Data were analyzed by using of descriptive statistics and MANCOVA method was used to analyze the research data was analyzed in SPSS.16 software. Results: The finds showed that the students in the experimental group reported less irrational beliefs, after intervention, as compared to those in the control group (P= < 0.005). Conclusion: we can use poetry therapy according to Sohrab sepehri poet for decrease irrational believes.
Biotechnology & nanotechnology
fereshteh jookar kashi; Zohreh Boroumand
Volume 28, Issue 1 , January and February 2021, , Pages 144-155
Abstract
Introduction: The bacteria with a remarkable ability to regenerate heavy metal ions are considered biological factories or important nano-factories to produce nanoparticles. The bacterial production of nanoparticles as a green and one-step method can overcome production problems and disadvantages through ...
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Introduction: The bacteria with a remarkable ability to regenerate heavy metal ions are considered biological factories or important nano-factories to produce nanoparticles. The bacterial production of nanoparticles as a green and one-step method can overcome production problems and disadvantages through physical and chemical methods. Materials and Methods: In this study, bacteria isolates were taken from soil samples of Nakhlak mine. One silver resistant bacterial strain was selected for the production of silver nanoparticles. This strain synthesized silver nanoparticles with supernatant and biomass. The nanoparticles synthesized were characterized using XRD and SEM. The antimicrobial activity of the nanoparticles was determined. Results: The silver resistance bacteria were isolated from soil samples. One silver resistant bacterial strain was selected for the production of silver nanoparticles. The nanoparticles showed good antimicrobial activity against standard strains of tested microorganisms. Conclusion: The nanoparticle synthesized by bacterial strain isolated from Nakhlak mine is a promising new biological source for synthesizing silver nanoparticles with potent antimicrobial activity. According to the results, this compound can be used to make disinfectants
Physiology & Pharmacology
Mahmoud Alipour; Farkhondeh Nemati
Volume 26, Issue 1 , March and April 2019, , Pages 145-152
Abstract
In the last few decades, research has been focused on the use of natural products for cancer therapy, such as crude plant extracts or some of different plant secondary metabolits. The objective of this study was to examine the invitro cytotoxic activities of crude ethanolic extract of leaf and flower ...
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In the last few decades, research has been focused on the use of natural products for cancer therapy, such as crude plant extracts or some of different plant secondary metabolits. The objective of this study was to examine the invitro cytotoxic activities of crude ethanolic extract of leaf and flower buds of Crataegus melanocarpa, on human MCF-7 and HeLa cell lines, with different concentrations, by Dye exclusion and Micro culture tetrazolium test (MTT) assay. The optical density (OD) colored solution was quantified at 570 nm wavelengths by an ELISA Reader, after 24, 48 and 72 h incubation. The results showed that ethanolic extracts, after 48h incubation, at in 5 and 10 mg/ml suppressed the proliferation of cancerous MCF-7 cells by significant diffrence with control group (p
Masoumeh Kashkouli; Saeedeh Ziaei
Volume 27, Issue 2 , July and August 2020, , Pages 267-273
Abstract
Introduction: Postpartum depression (PPD) is an episode of major depression that has many negative effects on the mother and the newborn child. Some factors have been identified as the predictive factors for PPD in peripartum such as Peripartum and Postpartum Depression, and preterm labor. The aim of ...
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Introduction: Postpartum depression (PPD) is an episode of major depression that has many negative effects on the mother and the newborn child. Some factors have been identified as the predictive factors for PPD in peripartum such as Peripartum and Postpartum Depression, and preterm labor. The aim of this study was to investigate the relationship between breastfeeding and PPD.Material and Methods: This research was a longitudinal study conducted in Darreh Shahr County, Ilam Province in 2015-2016. Of the 365 women who were pregnant about 38 weeks, 303 ones who had no depression according to the Edinburgh questionnaire were put under the study. The under study group was reexamined again with the Edinburgh questionnaire 6 to 8 weeks after delivery. 31 of them achieved grade 13 or greater of whom 29 ones were approved that had depression by a psychiatrist. The study was conducted on this group. Afterwards the relationship between breastfeeding and PPD and other effective variables including type of delivery, place of residence and etc, was investigated by dividing the samples into two groups namely depressed and non-depressed subjects. Results: Among the variables studied it was only breastfeeding that was connected to postpartum depression (P=0/004). This relationship was also positive (P =0/ 02) in the multivariate regression analysis.Conclusion: The results revealed that in the case of exclusive breastfeeding, the rate of PPD was decreased. Due to the high rate of prevalence of PPD
genetics
Shamim Ashrafi; farzaneh Tafvizi
Volume 25, Issue 2 , May and June 2018, , Pages 311-319
Abstract
Background: Unexplained infertility refers to cases in which the standard diagnostic procedures available do not lead to a specific cause for the infertility. Gln223Arg polymorphism was associated with high serum leptin and consequently obesity, polycystic ovarian syndrome and infertility. The aim of ...
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Background: Unexplained infertility refers to cases in which the standard diagnostic procedures available do not lead to a specific cause for the infertility. Gln223Arg polymorphism was associated with high serum leptin and consequently obesity, polycystic ovarian syndrome and infertility. The aim of this study was to investigate genetic variation of leptin receptor gene in unexplained infertile women. Materials and Methods: This case-control study was performed in 2015-2016. The subjects were 102 women with unexplained infertility and 112 fertile women with normal hormone profile. All participants gave their signature in consent document. After an overnight fasting, 5 CC blood sample was drawn from all subjects in the day 3 of menstruation. Genotyping of Gln223Arg polymorphism was performed using RFLP-PCR technique. Results: No significant association was observed between Gln223Arg polymorphism and unexplained infertility. The studied population was in Hardy-Weinberg equilibrium for Gln223Arg polymorphism. Therefore, there were not disturbing factors of Hardy-Weinberg equilibrium in the population. Conclusion: In present study, LEPR Gln223Arg polymorphism is not a risk factor for women with unexplained infertility. However, more studies on larger populations and the other leptin receptor polymorphism are suggested to understand the role of this polymorphism in women with unexplained infertility.
Mina Kanani; Parvaneh Nazar Ali; Parichehr Hanachi; Kaveh Khobeyri
Volume 23, Issue 2 , March and April 2016, , Pages 344-352
Abstract
Background & Objectives: The importance of omega-3 fatty acids as dietary supplements and its anti-inflammatory effects have been identified, so this study was aimed at determining the effects of omega-3 fatty acids supplementation and six weeks anaerobic exercise on changes in plasma levels of PGE2, ...
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Background & Objectives: The importance of omega-3 fatty acids as dietary supplements and its anti-inflammatory effects have been identified, so this study was aimed at determining the effects of omega-3 fatty acids supplementation and six weeks anaerobic exercise on changes in plasma levels of PGE2, CK, and LDH among active women. Methods: This study was a semi-experimental method with successive measurements. For the mentioned purpose, 32 healthy and active students (mean age of 22.41 ± 0.3 years, mean height 162.77± 2.1 cm, average weight 58.06± 2.0 kg and mean body mass index of 22.01±2.0 kg/m2) were randomly divided into 4 groups: control, supplements, exercise, exercise-supplementsand were studied for six weeks. ANOVA, Bonferroni test were used for statistical analysis and spectophotometry method was used for blood markers analysis. Results: The results showed that six weeks of aerobic exercise significantly increased CK and LDH and PGE2 (P=0.001) while these parameters were decreased in the exercise-supplementsgroup, although the reduction rates were not significant. The level of mentioned indices significantly decreased in the group that received only omega-3 (PGE2: P=0.05 and CK: P=0.034). Conclusion: According to achieved results; it can be deduced that CK, LDH and PGE2 levels increase during six weeks of aerobic exercise among active women. On the other hand, if omega3 supplements be taken during anaerobic exercises, the level of mentioned parameter will decrease.
genetics
nasser pouladi; mohammadali hosseinpourfeizi
Volume 25, Issue 3 , July and August 2018, , Pages 399-407
Abstract
Background: Thyroid cancer is the most common malignant endocrine tumor, and the incidence was rising worldwide over the last three decades. TP53 is one of the most important tumor suppressor genes in the genome, and its mutations are found in approximately 50% of human cancers. It plays pivotal roles ...
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Background: Thyroid cancer is the most common malignant endocrine tumor, and the incidence was rising worldwide over the last three decades. TP53 is one of the most important tumor suppressor genes in the genome, and its mutations are found in approximately 50% of human cancers. It plays pivotal roles in the regulation of cell cycle arrest and apoptosis. The aim of this study was to analyze TP53 gene mutations among thyroid cancer patients in East- Azerbaijan. Material and Methods: 40 tumor samples have been collected from thyroid cancer patients from Tabriz hospitals between 2007-2009. DNA was extracted by Proteinase K – Iso propanol method and then the mutations in p53 gene from exon5 to exon8, were detected by Polymarase Chain Reactions (PCR) and direct sequencing techniques.Results: Alterations in the p53 gene were detected in 12.5% of the patients, including single nucleotide polymorphisms and mutations, including codon216 (GTG>GTA), codon215 (AGT>ATT) and codon273 (CGT>CAT) mutations (each mutation in one of the cases) and two linked polymorphisms 14181C>T and 14201T>G (in two cases).Conclusion: This result helps us to clarify p53 mutation status among Azerbaijani thyroid cancer patients.
Educational
homyra vahdati; Ali mohammad Naemi
Volume 27, Issue 3 , September and October 2020, , Pages 441-451
Abstract
The present study examine The relationship between Information and Communication Technology and Organizational Agility with the mediating role of Targeted Organizational Forgetting among the employees of Sabzevar University of Medical Sciences. The method of research is descriptive and its type is correlation ...
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The present study examine The relationship between Information and Communication Technology and Organizational Agility with the mediating role of Targeted Organizational Forgetting among the employees of Sabzevar University of Medical Sciences. The method of research is descriptive and its type is correlation with an emphasis on structural equations. The population consisted of all employees of Sabzevar University of Medical Sciences (205 persons) that 134 peoples were selected using on cochrane formula based.That sample was selected by Systematic sampling. The data was collected through ict Muharrampor, Organizational Agility by Sharifi & Zhang,Targeted Organizational Forgetting by Mahmoudvand questionnaires. To evaluate validity and reliability of the questionnaires we used Cronbach Alpha coefficient The Pearson correlation and structural equation modeling (SEM) was used for data analyzing. The results showed that:1) There is a significant and positive relationship between the Ict and Organizational Agility. 2) There is a significant and positive relationship between the Ict and Targeted Organizational Forgetting. 3) There is a significant and positive relationship between the Targeted Organizational Forgetting and Organizational Agility. 4) Targeted Organizational Forgetting playing a mediating role in relationship between Ict and Organizational Agility and 45% of Organizational Agility was predicted by Ict with the mediation of Targeted Organizational Forgetting.
Microbiology
sima nobari; Ezzat Nourizadeh
Volume 28, Issue 3 , May and June 2021, , Pages 449-456
Abstract
Introduction: Leishmaniasis is a disease in tropical regions, that includes a wide range of clinical protests, from skin lesions to fatal visceral infections. A2 gene is accounted as one of the most reliable genetic factors cause visceral form. This gene is a single copy without functional expression ...
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Introduction: Leishmaniasis is a disease in tropical regions, that includes a wide range of clinical protests, from skin lesions to fatal visceral infections. A2 gene is accounted as one of the most reliable genetic factors cause visceral form. This gene is a single copy without functional expression in the species causing skin form of the disease such as L. major and L. tropica. The aim of our study is to evaluate A2 gene sequence in the strains that cause skin form of disease and compare it with other exception strains of the Leishmania tropica strains in Iran.
Materials and Methods: Leishmania species were detected using ITS1 and ITS2. The parasites were injected into BALB/c mice and monitored of footpad inflammation in BALB/c mice. after a certain period of time the mice were killed and their visceral organs were examined for the presence of parasites. Finally, A2 gene sequence analyzed.
Results: A2 gene in a strain causing visceral form was different to a gel electrophoresis pattern of skin form causing strains. Also, the gel electrophoresis pattern of A2 gene in strains causing skin form was different to previous reports of cutaneous leishmaniasis.
Conclusion: The results of this recent experiment showed that the gel electrophoresis pattern of A2 gene in especial strains causing viseral form was similar to previous reports of visceral leishmaniasis. It seems that this gene may play an important role in the visceral ability of specific strains of Leishmania tropica.
Mahnaz Torabi-Hokmabadi; Ahamd Alahabadi; Abolfazl Rahmani-Sani; Somayyeh Zarei-Tazarghi; Hamidreza Karimi-Sani; Mohamadreza Behrozikhah
Volume 23, Issue 3 , July and August 2016, , Pages 504-515
Abstract
Background Painkillers such as diclofenac are widely used in human medicine and veterinary medicine. Because of their excretion into water resources and subsequent environmental hazards, their removal from the waters and wastewaters is essential. Since, these drugs cannot undergo biodegradation, an advanced ...
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Background Painkillers such as diclofenac are widely used in human medicine and veterinary medicine. Because of their excretion into water resources and subsequent environmental hazards, their removal from the waters and wastewaters is essential. Since, these drugs cannot undergo biodegradation, an advanced treatment such as adsorption method must be applied for their removal and one of the best adsorbents in this regard is activated carbon. This study aimed to investigate the removal of diclofenac contaminant by NH4Cl-induced activated carbon.Materials & Methods Activated carbon produced from agricultural wastes was impregnated with ammonium chloride (NH4Cl) and activated at 800°C. The experiments were conducted in a closed system using a magnet stirrer at 100 rpm. In this investigation, the effects of several variables, namely adsorbent concentration, contact time, pH, and temperature, on the removal of diclofenac were evaluated. Then, isotherms and adsorption thermodynamic were explored. We used DR 5000 spectrophotometer model for drug analysis with the wavelength of 275 nm.Results The produced NAC (NH4Cl-induced activated carbon), having the special surface of 1029 m2/g and pores volume of 2.46 nm, was able to remove 0.81% of diclofenac from a solution of 50 mg/L at the sorbent concentration of 0.8 mg/L, pH 6, in 20 minutes time. The equilibrium adsorption experiments showed that the absorption of diclofenac on NAC followed the Longmuir model and the absorption capacity was 212.5 mg/g. Using the diclofenac concentration of 50 mg/L and other optimal conditions, thermodynamic studies of diclofenac absorption on NAC showed that the amount of drug removal increased from 73% to 95% with increasing temperature from 10°C to 40°C. Conclusion NAC can be used as a convenient and inexpensive adsorbent for the removal of diclofenac and other drug compounds from polluted waters and wastewaters.
Foad Alimoradi; Shabnam Jaliloghadr; Amir Javadi; Maryam Javadi
Volume 22, Issue 4 , September and October 2015, , Pages 676-684
Abstract
Background and Objectives: Lipid disorders, which are associated with the risk factors for cardiovascular diseases, are increasing in adolescents. Studies are indicative of the relationship of blood lipid level and chronic diseases with anthropometric indices in adolescents. This study aims to investigate ...
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Background and Objectives: Lipid disorders, which are associated with the risk factors for cardiovascular diseases, are increasing in adolescents. Studies are indicative of the relationship of blood lipid level and chronic diseases with anthropometric indices in adolescents. This study aims to investigate lipid disorders and their relationship with anthropometric indices in adolescents. Materials and Methods: The sample of this descriptive and analytical study included 318 adolescents aged 10-18 who were selected and analyzed using stratified random sampling. The subjects’ demographic, anthropometric and biochemical data were obtained. The data were then analyzed using t-test, chi-square and ANOVA. Findings: Of the subjects, 19.5% had a total cholesterol above 170 mg/dl, 33.7% had a triglyceride level above 100 mg/dl, 12.6% had an LDL cholesterol level above 110 mg/dl, and 41% had an HDL cholesterol level below 40 mg/dl. The increase in BMI, waist circumference, waist to hip ratio, and waist to height ratio was accompanied by increased lipid disorders. Significance level was considered as 0.05. Conclusion: Although the use of anthropometric indicators alone cannot indicate the condition of the blood lipid profile in adolescents, but they can be used as a simple and accessible method.