Nursing
Vajihe Jafari; Mohammad Bodaghabadi; Mohammad Bidkhori; Mostafa Rad
Abstract
Introduction: Daily activities and social functions of the elderly are affected with the progress of their cognitive changes. The purpose of this study was to determine the cognitive status and factors related to it in the elderly of Sabzevar city.Materials and Methods: This is a descriptive-analytical ...
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Introduction: Daily activities and social functions of the elderly are affected with the progress of their cognitive changes. The purpose of this study was to determine the cognitive status and factors related to it in the elderly of Sabzevar city.Materials and Methods: This is a descriptive-analytical study was conducted in Sabzevar city in 2022. In this research, 350 elderlies over 60 years in a cluster method were entered to study from urban health centers. To collect information, demographic, geriatric depression scale (GDS-15) and Mini–Mental State Examination (MMSE) were used. Data analysis were done using descriptive statistic (mean, standard deviation, and frequency distribution tables) and inferential statistic (multiple logistic regression test).Results: The mean of the age was 66.85±6.64 with a minimum 60 and a maximum age of 88 year. The results showed that 75% of the elderly had normal cognitive status and 25% had cognitive impairment. By using the multiple logistic regression, age (OR = 1.07, p = 0.003), marital status (OR = 3.01, p = 0.03), number of children (OR = 1.24, p = 0.02) type of residence (OR=4.09, p>0.001), occupation (OR=3.09, p=0.04), body mass index (OR=0.9, p=0.006)), diet (OR = 5.55, p = 0.01) and depression (OR = 2.92, p = 0.03) had a statistically significant relationship with cognitive status.Conclusion: Due to the frequency of cognitive disorders in the elderly it is suggested that health care providers perform cognitive screening in the elderly in order to prevent the development of cognitive impairment in this vulnerable group.
Psychology
hamid yaghoutimoghaddam; Frshad jaberi Koshki; mahnaz haghnazar; hamid sadeghi; mohammad hosein zadeh hesari
Volume 27, Issue 6 , January and February 2021, , Pages 788-794
Abstract
Introduction: Workaholism can be enjoyable, but at the same time, frustrating and problematic with positive and negative repercussions. This study was conducted to investigate the relationship between workaholism and depression and anxiety levels in specialist physicians of hospitals affiliated to Sabzevar ...
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Introduction: Workaholism can be enjoyable, but at the same time, frustrating and problematic with positive and negative repercussions. This study was conducted to investigate the relationship between workaholism and depression and anxiety levels in specialist physicians of hospitals affiliated to Sabzevar University of Medical Sciences during 2017-2018.
Materials and methods: This correlation study, The statistical population of this study included all specialist physicians in hospitals affiliated to Sabzevar University of Medical Sciences that selected by census method. The research instruments used were Beck Depression Inventory, and Spielberger state-trait anxiety inventory, The Spence and Robbins Questionnaires also were used for workaholism. For analyzing data, SPSS-20 software and descriptive and inferential statistical methods (Correlation Coefficient, Regression) were applied.
Results: The results indicated that there was a significant and relatively strong relation between workaholism and its components with anxiety and depression (p<0/05). Workaholism can also predict depression and anxiety (p<0/05).
Conclusion: The current study shows that work can be a reason of diseases if employees get addicted to it. Thus organizations should pay more attention to this fact that working hard in work place, is not always beneficial for individuals and organization both. So managers have to consider ways to prevent these dangerous consequences which can be harmful for their employee’s health.
Psychology
saeedeh azaraeen; Roshanak khodabakhsh; Zohre Khosravi; Masoud Fazilatpur
Volume 27, Issue 4 , November and December 2020, , Pages 494-501
Abstract
Introduction: Brain-Behavioral Systems contribute to the development of wide variety of emotional disorders, including anxiety and depression. The aim of this study was to compare the Brain- Behavioral Systems in patients with anxiety, patients with depression, and healthy individuals.
Materials ...
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Introduction: Brain-Behavioral Systems contribute to the development of wide variety of emotional disorders, including anxiety and depression. The aim of this study was to compare the Brain- Behavioral Systems in patients with anxiety, patients with depression, and healthy individuals.
Materials and Methods: This study was a cross-sectional study in which 45 individuals with anxiety (moderate to high score in Beck Anxiety Inventory (BAI) and low score in BDI-II) and 45 individuals with depression (moderate to high score in Beck Depression Inventory-II (BDI-II) and low score in BAI) who referred to private and public health centers in Jiroft were selected through purposive sampling and matched with 45 healthy individuals (low score in BDI-II and BAI) for age and gender. After informed consent, participants were asked to fill the questionnaires including Jackson-5 Scale, 2nd version of Beck Depression Inventory (BDI-II), and Beck Anxiety Inventory (BAI) and were allocated to different groups based on the score of the questionnaires. Data were analyzed using one-way analysis of variance by spss21 software.
Results: Result showed that there were significant differences between three groups in Behavior Inhibition System, Fight, Flight and Freeze. Also, the differences were not significant in Behavioral Activation System.
Conclusion: Given the different functions of the Brain -Behavioral Systems in patients with anxiety, patients with depression, and healthy individuals, this theory may explain the etiology of anxiety and depression.
Psychology
Saeed Reza Amirian; Mojtaba Amiri Majd; Mansure Shahriari Ahmadi; leila elyasi
Volume 27, Issue 3 , September and October 2020, , Pages 404-412
Abstract
Background and objectives: Mothers of children with autism spectrum disorder suffer from stress, anxiety and depression. The aim of this study was to determine the Mindfulness-Based Positive Behavior Support on stress, depression and anxiety of these mothers.Methods: Thirty mothers with children aged ...
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Background and objectives: Mothers of children with autism spectrum disorder suffer from stress, anxiety and depression. The aim of this study was to determine the Mindfulness-Based Positive Behavior Support on stress, depression and anxiety of these mothers.Methods: Thirty mothers with children aged 6-8 years old with autism spectrum disorder were selected randomly from Gorgan Special Schools and were randomly divided into 2 groups of intervention and control. An expert psychiatrist educated MBPBS to the intervention group in 8 sessions. The assessment tools included the Perceived Stress Scale, Beck Depression and Anxiety Inventory, completed by all mother before, immediately and one month after the intervention. Independent t-test was used to compare the two groups. Results: Before intervention, mean scores of depression, anxiety and stress in mothers of autistic children were not significantly different between the intervention and control groups, but the mean scores of the two groups were significantly different after intervention and one month after the intervention; mean scores of depression, anxiety and stress of mothers of autistic children did not change significantly in the control group over time, but decreased significantly in the intervention group (P
Psychology
Mohammad Azad Manjiri; Ebrahim Namani
Volume 27, Issue 3 , September and October 2020, , Pages 463-473
Abstract
Introduction: Inappropriate emotional reactions such as anxiety and depression is very evident in today’s societies, affecting and causing too many problems for nurses, then effect on the quality of providing health cares. According to the nurses' exposure to mental health disorders, the purpose ...
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Introduction: Inappropriate emotional reactions such as anxiety and depression is very evident in today’s societies, affecting and causing too many problems for nurses, then effect on the quality of providing health cares. According to the nurses' exposure to mental health disorders, the purpose of the present research is to study empathy moderating role in relationship between psychological capital with depression and anxiety of nurses.
Materials and Methods: This research is an exploratory research of correlation plans. Based on Morgan Table were selected 217 subjects of employed nurses (100 male and 117 female) as hospitals of Sabzevar in spring 2018 by available sampling. In order to obtain data, Luthans et al (2007), psychological capital questionnaire, Baron-Cohen empathy(2003), and Anxiety and Depression Scale of Zigmond and Snaith Hospital (1983),were used. Data were analyzed by Pearson correlation coefficient and multivariate regression analyses by SPSS-22 software.
Results: Findings of the present research showed that there are negative significant relationship between psychological capital and hospital of anxiety and depression of nurses (p<0.01). also empathy is mediating role in relationship between psychological capital and clinical symptoms of anxiety and depression(p<0.01).
Conclusion: According to the findings of the research, it can be concluded that empathy can be mediated relationship psychological capital and hospital clinical symptoms of depression and anxiety.
Physiology & Pharmacology
Jafar Ahmadpouri; saeid valipour chahardah charic; mahbubeh setorki
Volume 27, Issue 3 , September and October 2020, , Pages 475-482
Abstract
Introduction:Severe stressful incidents are associated with the risk of mental disorders such as depression and anxiety. Regarding the adverse effects of anti-depressants/anxiety drugs, researcher’s attention have been focused on finding natural ingredients. The aim of the present study was to ...
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Introduction:Severe stressful incidents are associated with the risk of mental disorders such as depression and anxiety. Regarding the adverse effects of anti-depressants/anxiety drugs, researcher’s attention have been focused on finding natural ingredients. The aim of the present study was to investigate the effect of Adiantum capillus veneris extract on depression and anxiety induced by acute stress in male rats.
Materials and Methods: In this experimental study, 40 male Balb/C mice were randomly divided into 5 groups including control group (under acute stress receiving normal saline), intervention groups (under acute stress receiving extract of Adiantum capillus venerisat doses of 100, 200 and 400 mg/kg), and positive control (under acute stress receiving diazepam). Acute stress was induced by electric shock (0.5 mA, 2 min) and immobilization in restrainer (2 hours) for one time. Extract and drug were administered intraperitoneally for 21 days and then anxiety, depression and Motor activity were evaluated by forced swimming, elevated plus maze (EPM) and open filed tests respectively.
Results: Treatment of stressed mice with different doses of Adiantum capillus veneris extractsignificantly decreased the immobility time in the forced swimming test in comparison with the control group (P <0.05). Treatment of stressed mice with 400 mg/kg of Adiantum capillus veneris extractsignificantly increased the entry into the open arms and significantly decreased the number of entery into the closed arms of EPM (P<0.05). Different doses of extract had no significant effect on the number of line-crossing in the open field test as compared with the control group.
Conclusion: Adiantum capillus veneris extract showed antidepressant and anti-anxiolytic effects in mice under acute stress.
Psychology
majid pourfaraj omran; Abbas Bakhshipour; Majid Mahmoud Alilou
Volume 27, Issue 2 , July and August 2020, , Pages 155-162
Abstract
Background: With attention to considered various cognitive beliefs in psychopathology of disorders, the purpose of this study was comparison of cognitive beliefs include; thought action fusion (TAF), responsibility and the overestimation of threat (RT), and overimportance and control thoughts (ICT), ...
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Background: With attention to considered various cognitive beliefs in psychopathology of disorders, the purpose of this study was comparison of cognitive beliefs include; thought action fusion (TAF), responsibility and the overestimation of threat (RT), and overimportance and control thoughts (ICT), perfectionism and the intolerance of uncertainty (PC) in obsessive –compulsive disorder (OCD), generalized anxiety disorder (GAD), major depression disorder (MDD) and normal group for more clarification psychopathology of these disorders. Materials & Methods: This study is causal-comparative research. The clinical samples include patients with OCD, GAD and MDD that referred to Sari Shahid Zareh hospital in 2015. From each of these clinical groups and normal people, 30 persons were selected available sampling method and accomplish obsessive beliefs questionnaire and thought action fusion scale. Data were analyzed by MANOVA.Results: The result of MANOVA and Tukey posthoc test showed that OCD group were significantly higher than other groups in TAF, RT and ICT (p
Psychology
Khadijeh Fouladvand
Volume 26, Issue 6 , March and April 2020, , Pages 727-737
Abstract
Background and Objectives: Although studies have examined the relationship between depression and self-efficacy with decision making, but the role of these factors has not been considered in choosing the type of decision making style. Therefore, the aim of the current study was to investigate the role ...
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Background and Objectives: Although studies have examined the relationship between depression and self-efficacy with decision making, but the role of these factors has not been considered in choosing the type of decision making style. Therefore, the aim of the current study was to investigate the role of depression and self-efficacy in predicting the decision making styles among adolescents.Materials and Methods: This research was a type of correlation. The statistical population of the study consisted of every high schools students in Lorestan province, Iran. 300 adolescents [155 boys, 145 girls] were selected through multiple cluster sampling method. The data were collected through Scott and Bruce decision making styles questionnaire (DMSQ), Kovacs and Beck children's depression inventory (CDI) and Muris self-efficacy questionnaire-children (SEQ-S). The obtained data were analyzed through Pearson correlation coefficient and multiple regression. Results: The results of regression analysis indicated that the components of the depression and self-efficacy significantly predicted 32.5%, 29.9%, 3.5%, 17.2% and 9.5% of the variance of rational, intuitive, dependent, avoidance and spontaneous, respectively (p
Psychology
Maryam Taher Pour; Ahmad Sohrabi; Mehdi Zemestani
Volume 26, Issue 4 , November and December 2019, , Pages 505-513
Abstract
AbstractAims: Eating disorders are characterized by persistent eating disorders or eating behaviors that leading to significant damage on physical and psychosocial function. This study aimed to examine the efficacy of compassion-focused therapy on improving symptoms of depression, anxiety and stress ...
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AbstractAims: Eating disorders are characterized by persistent eating disorders or eating behaviors that leading to significant damage on physical and psychosocial function. This study aimed to examine the efficacy of compassion-focused therapy on improving symptoms of depression, anxiety and stress and weight self-efficacy in women with eating disorders (restrictive type). Materials & Methods: In a quasi-experimental design pretest-posttest control group design, a total of 30 girls of University of Kurdistan at the year between 2014-2015 who had higher range at determined cut-off point in Revised Rigid Restraint Scale, after initial clinical assessment and qualifications of the study, purposive sampling method selected and randomly assigned to two experimental (Compassion-Focused Therapy, n=15) and control groups (n=15). Data collection tools were Depression, Anxiety and Stress Scale (DASS), and Weight Efficacy Lifestyle Scale (WELS) that subjects before and after the intervention were assessed by this tool. In order to analyze the data, multivariate analysis of covariance (MANCOVA) was used.Results: Outcome of the experimental group received 8 sessions focused therapy showed that treatment focused on compassion have effect on improving depression (F=93.15, P
Nursing
Mahdi Jafarzadeh Fakhari; Yaser Tabaraie; Mahdi Motakef far; Salime Azizi
Volume 25, Issue 1 , May and June 2018, , Pages 111-117
Abstract
Introduction:Depression is one of the most common psychiatric disorders in patients with diabetes that its incidence in addition to the impact on the course of treatment, can be changed the prognosis. This study aimed to determine the effects of progressive muscle relaxation on depression in patients ...
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Introduction:Depression is one of the most common psychiatric disorders in patients with diabetes that its incidence in addition to the impact on the course of treatment, can be changed the prognosis. This study aimed to determine the effects of progressive muscle relaxation on depression in patients with type 2 diabetes. Methods & Materials: This study was a clinical trial that conducted on 77 patients who referred to Diabetes center of Sabzevar city. The participants completed the Beck Depression Inventory and if they earned 14-28 (mild to moderate depression), included to study. Then, participants after consent, were divided Randomly into two groups of progressive muscle relaxation (n= 37) and control (n= 40).relaxationperformed 2 times a week for 20-30 minuteswithin 6 weeks, under the supervision of a researcher. Beck Depression Inventory was completed at the end of the sixth week again.In analytic measurements of this study used of statistical analysis in SPSS software (Version 16). A P value of < 0.05 was considered to be statistically significant. Results: The mean depression score after intervention in relaxation group compared to control group was ranged from 20.91±4.20 to 11.29±2.85 and from 20.60±4.21 to 19.99±3.61, respectively.According to independent t-test, there was significant differencebetween case and control groups (P<0/001). Paired t-test showed statistically significant difference in terms of depression scores before and after intervention(P<0/001); while in control group had not any statistical significancy (p=0.204) Conclusion:Progressive Muscle Relaxation is effective way to reduce depression in patients with diabetes type 2.
Kazem Ashrafi; Robab Sahaf; Farahnaz Mohammadi Shahbalaghi; Akram Farhadi; Gholamreza Ansari; Farid Najafi; Azizeh Gharanjik; SHadi Ghaderi
Abstract
Objectives The population aging is a pretty new phenomenon and psychological disorder is one of the most important problems associated with the elderly communities. In ethnic societies, there are some barriers in the elderly that could impede the diagnosis of psychological and mood disorders such as ...
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Objectives The population aging is a pretty new phenomenon and psychological disorder is one of the most important problems associated with the elderly communities. In ethnic societies, there are some barriers in the elderly that could impede the diagnosis of psychological and mood disorders such as depression. The current cross sectional study investigated the demographic characteristics, prevalence of depression, and some social factors and personal health problems of 60 Iranian Azeri Turkish elderly cases who stayed home.Methods The current cross sectional study was conducted on 300 Iranian Azeri Turkish elderly who participated in the study voluntarily and had no cognition impairment. Samples were selected randomly. The study participants filled out a questionnaire containing demographic information, health status and diseases antecedent; the questionnaire of depression in the elderly (GDS-15) was also completed by interviewing the cases. Collected data were analyzed by SPSS version 16 employing t test, Chi-square test, and ANOVA. Results The mean age of the study cases was 70±7.2 years in males and 69±6.5 years in females. Based on the results of the current study, the mean score of depression in the study cases was 4.62±3.53. The prevalence of minor depression was 28%, moderate depression 10.3%, and major depression 6.3%; also, 55.4% were asymptomatic. There was a significant statistical relationship between depression score and gender (P<0.001), occupational status (P<0.001), educational level (P=0.01), physical activity (P=0.02), chronic diseases (P<0.001), hearing impairments (P=0.007), and problems with kidney and urinary tract (P=0.04), gastrointestinal (P<0.001) and musculoskeletal systems (P<0.001); there was no significant statistical relationship between the mean score of depression and the place of living (urban or rural residence), level of income, and living together (P≥0.05). Conclusion Depression is one of the most important diseases in aging period. The prevalence of minor and moderate depression among Azeri elderly is lower or similar to those of other studies in Iran. The result indicated a positive and significant relationship between depression and some health status variables. Hence, it is recommended to apply screening programs to identify elderly who are at risk for psychological disorders and also define measures to improve their life satisfaction, health status, and the quality of life.
Sajad Aminimanesh; Jafar Hasani; Mohammad Nikoosiar Jahromi; Mehdi Taheri; Hasan Rezaee Jamalooei
Abstract
Objectives Insomnia is one of the common disorders whose relationship with depression and anxiety is widely discussed. The current study aimed at investigating the epidemiology of insomnia and its relationship with depression and anxiety among male prisoners. Methods In the current study, 110 male prisoners ...
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Objectives Insomnia is one of the common disorders whose relationship with depression and anxiety is widely discussed. The current study aimed at investigating the epidemiology of insomnia and its relationship with depression and anxiety among male prisoners. Methods In the current study, 110 male prisoners were selected through the convenient sampling method. To collect data, Pittsburgh sleep quality index, Beck depression inventory, and Beck anxiety inventory were used. Data were analyzed using multiple regression analysis and Pearson correlation coefficient.Results Depression and anxiety had a significant relationship with insomnia (P<0.0001). The results of multiple regression analysis showed that depression and anxiety could predict the insomnia with 0.29 variance.Conclusion Given the high prevalence of insomnia among prisoners and its relationship with depression and anxiety, it seems necessary to provide psychological services to decrease insomnia and its underlying factors.
Sepideh Tarbali; Shiva Khezri
Volume 22, Issue 5 , November and December 2015, , Pages 815-822
Abstract
Background: Depression is the most common psychological symptoms in multiple sclerosis (MS) patients. The exact cause of the high rate of depression in these patients is unknown, and a combination of neurological factors, including the loss of nerves coverage and psychosocial are involved. The hippocampus ...
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Background: Depression is the most common psychological symptoms in multiple sclerosis (MS) patients. The exact cause of the high rate of depression in these patients is unknown, and a combination of neurological factors, including the loss of nerves coverage and psychosocial are involved. The hippocampus is extremely vulnerable to neurological diseases and has an important role in mood disorders such as depression. This study aimed to determine the effects of vitamin D3 on improving depression was conducted in an experimental model of MS.
Materials and Methods: For demyelination induction, 2µl lysolecithin was injected streotaxically into the CA1 area of hippocampus in male rat. Animals treated with vitamin D3, received 5μg/kg vitamin D3 for 7, 14 and 21 days post lesion with intraperitoneal injection. The forced swimming test was applied to determine the depression.
Results: Administration of lysolecithin as the inducer of MS disease caused demyelination and depression. In lysolecithin treated animals the immobility time as an indicator of depression in the forced swimming test on 14 day and 21 day post lesion showed a significant increase compared to the control group. While the administration of vitamin D3 for 14 and 21 days caused improvement of depression compared to the group receiving lysolecithin alone.
Conclusion: It seems prescribing of vitamin D3 at dose of 5μg/kg can improve depression in an experimental model of MS. However, evaluation of effects of vitamin D3 on the depression in MS patients, requires much more extensive studies.
Korosh Bani Hashem; Fatemeh Golestan Jahromi; Nikzad Ghanbari; Mansour Moazen
Volume 21, Issue 5 , September and October 2014, , Pages 735-742
Abstract
Background and purpose: Stress Inoculation Training has positive effect onreducing tension in patients with cancer, but this intervention hasn’t done in patients with prostate cancer yet, so the purpose of present study is to investigate the effect of stress inoculation training on depression and ...
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Background and purpose: Stress Inoculation Training has positive effect onreducing tension in patients with cancer, but this intervention hasn’t done in patients with prostate cancer yet, so the purpose of present study is to investigate the effect of stress inoculation training on depression and anxiety in patient with prostate Cancer.
Materials and Methods: The statistical society of this study included men with prostate cancer who had refered to the Cancer Therapy Centers of Kermanshah in Feb 2014. 30 participants were randomly selected and divided in two groups (15 per group) of control and experiment. The applied instrument in this research was SCL-90-R scale. In order to perform data analysis, MANCOVA was used and results were extracted from SPSS software version 20.
Results: Results indicated that stress inoculation training have had a significant effect on reducing anxiety and depression in patients with prostate cancer of experiment group compared with control group (F=11/72 and P=0/002 for depression and F=21/87 and P
،شاثقثا »شسانشقه; ءشسخخئثا ّخمشیرشدیه; آشتشق ُشیثلاه; Azar Asadabadi
Volume 21, Issue 5 , September and October 2014, , Pages 769-777
Abstract
Background and purpose: Diabetes is a common disease in Iran and around the world which is associated with veriety of costly complications Depression is one of the most important problems diabetics deals with. Nurses can have a significant role in stress management training in order to improve the life ...
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Background and purpose: Diabetes is a common disease in Iran and around the world which is associated with veriety of costly complications Depression is one of the most important problems diabetics deals with. Nurses can have a significant role in stress management training in order to improve the life quality of these patients. This study was aimed at evaluating the effectiveness of training patients with Type II diabetes in stress management, on depression.
Materials and Methods: In this Clinical trial research 96 patients with type II diabetes were selected from patients who had refered to the Diabetes Center of Kerman in 2013, and were asked to complete the DASS21 questionnaires, considering common consent. Patients, who had depression, were randomly divided into two groups: experimental and control groups and stress management training was done. Data were collected using questionnaires (Beck = DASS), respectively. Test data covariance, repeated measures ANOVA and SPSS software version 18 were used for analysis at Significant level of p< 0.05.
Results: Mean and standard deviation of depression before intervention in control group and test group, were respectively33.37± ( 13.94) and 32.77± (13.58), and after the intervention, obtained magnitudes for mentioned parameters were respectively 31.34± (13.91) and 20.77± (10.42). Comparing to pre-intervention period, standard deviation of depression has decreased and 51.2% of the experimental group's patients were found less depressed after being trained with the stress management tour. significant different between severity of depression before and after implementation of stress management training were resulted.(p-value= 0/0001).
Conclusions: Stress management training has played an effective role in reducing depression.
Batol Haj Ebrahimi; Mohammad Kazemi Arab Abadi
Volume 20, Issue 3 , September and October 2013, , Pages 380-389
Abstract
Depression is a main complication in the developed and in developing countries. Studies showed that depression not only is a emotional disease but also affect the body. Immune system disordering is an important complication following depression. Studies showed that depression can induce immunological ...
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Depression is a main complication in the developed and in developing countries. Studies showed that depression not only is a emotional disease but also affect the body. Immune system disordering is an important complication following depression. Studies showed that depression can induce immunological chronic inflammation, hence, lead to accelerate depression. Several molecules including JAK/STAT pathways and Toll like receptors, AIMII and NLRs play important roles in inducing chronic inflammation. It seems that the mentioned molecules can induce inflammation via cytokine production in depressed patients. Therefore, evaluation of cytokine patterns and cytokines producing pathways in depressed patients can help scientists to find the pathogenesis of depression. Thus, the aim of this review article was to collect recent information regarding cytokine patterns as well as the related molecules in inflammation in depression.
Mahmoodreza Azarpajooh; Naghmej Mokhber; Negar Asgharipour
Volume 20, Issue 1 , March and April 2013, , Pages 6-14
Abstract
Background: Post stroke depression is a common state after stroke causing disability and affects cognitive status in patients. Present study tried to show the effect of citalopram on post stroke depression as well as cognitive state. Materials and methods: in clinical trial study all patients with ...
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Background: Post stroke depression is a common state after stroke causing disability and affects cognitive status in patients. Present study tried to show the effect of citalopram on post stroke depression as well as cognitive state. Materials and methods: in clinical trial study all patients with acute ischemic stroke who had been consecutively admitted to the Ghaem Hospital (from 1388-1389), in Mashhad were evaluated for inclusion in the study.(218 person).In first visit neurological tests and hamilton rating test for depression were taken. At last 89 patients admitted az sample of study. Cognitive impairment was assessed with the Dementia Rating Scale (DRS). The severity of the depressive symptoms was measured by Hamilton Rating Scale for Depression (HAM-D).Then they were classified into those with severe depressive symptoms (HAM-D >20; N=18), with mild depressive symptoms (HAM-D scores 12-19; N=39) and non-depressed patients (HAM-D scores < 12; N=32). Patients with severe depressive symptoms were treated with citalopram. Statistical analysis was performed using spss version 11.
Results: HRDS, MMSE and DRS scores had significant change at the baseline and the end of study in group treated by citalopram. There were significant differences between DRS scores in attention domain at the baseline and the end of study in both citalopram group and without depression. Conclusion: These data suggest that treatment of depressive symptoms in the acute phase of stroke improves both mood and cognition and would be a reasonable treatment for patients suffering post stroke depression and cognitive change after stroke
Z ABEDIAN; SR MAZLOOM; Z SHOJAEIAN; N MOKHBER
Volume 12, Issue 1 , March and April 2005, , Pages 37-43
Abstract
Background and purpose: Hormonal changes, hot flush and peri-menopausal crises affect women's mental; health and predisposes them to depression. Hormone replacement therapy is applied to treat menopausal symptoms but its effect on depression is in question. Therefore / this research is Conducted to determine ...
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Background and purpose: Hormonal changes, hot flush and peri-menopausal crises affect women's mental; health and predisposes them to depression. Hormone replacement therapy is applied to treat menopausal symptoms but its effect on depression is in question. Therefore / this research is Conducted to determine the effect of hormone replacement therapy on menopausal depression.
Methods and Materials: In this quasi - experimental study 40 menopausal women from Mashad, with no history of hormone therapy psychiatric disorders and no Contraindication of hormone therapy, were selected and divided into 2 groups according to their own tendency. The experimental group received 0.625 mg conjugated estrogen and 2.5 mg medroxy progesterone acetate daily for six weeks; the control group received nothing. Sample selection checklists, demographic questionnaire, Beck's depression inventory, premenstrual syndrome test, Cassidy social support scale, Uzeng self- esteem, and attitudes toward menopause and hormone therapy were utilized for data collection. The obtained data were analyzed in SPSS using independent and paired t- tests, as well as two - way ANOVA.
Results: mean depression score at the outset for the control and experimental groups were 21.85±8.4 and 20.25±7.5 and at the end of the study 17.00±8.7 and 15.5±7.6 respectively; this implied a significant difference in each group. However, the difference between the two groups was not significant.
Conclusion: The results indicated no significant different in utilizing or not utilizing Hormone Replacement therapy on menopausal depression. Therefore, longitudinal and more extensive researches are recommended to Study the issue.