Physical Education
zohreh mirzavand; mohammad fathi; mostafa bahrami
Abstract
Introduction: Inactivity plays a role in diabetes and increasing tissue oxidative stress and this study aimed to investigate the effect of a period of aerobic exercise on malondialdehyde, superoxide dismutase, and glutathione peroxidase in the heart tissue of male diabetic rats.
Materials and Methods: ...
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Introduction: Inactivity plays a role in diabetes and increasing tissue oxidative stress and this study aimed to investigate the effect of a period of aerobic exercise on malondialdehyde, superoxide dismutase, and glutathione peroxidase in the heart tissue of male diabetic rats.
Materials and Methods: 44 male Wistar rats (200-250 grams) were randomly divided into 4 ten groups of healthy, diabetic, training, and diabetes+ training. After 12 hours of food deprivation, diabetes was induced by intraperitoneal injection of STZ solution, The training groups did aerobic exercise 5 days a week for 6 weeks. 48 hours after completion of the protocol, anesthetized animals and heart tissue were removed. ELISA method was used to measure the amount of superoxide dismutase, malondialdehyde, and glutathione peroxide. Data were analyzed with one-way ANOVA, Tukey's post hoc tests, SPSS, and GraphPad software.
Results: The results showed that superoxide dismutase and glutathione peroxide in the diabetes group were significantly lower than the control, exercise, and diabetes+exercise groups (p≤0.0001). Also, superoxide dismutase and glutathione peroxide were significantly higher in the diabetes+exercise group than in the control and exercise groups (p≤0.0001). Malondialdehyde in the diabetes group was significantly higher than in the diabetes+exercise group, the exercise group, and the control group (p≤0.0001). Malondialdehyde was significantly higher in the diabetes+exercise group than in the diabetes and control groups (p≤0.0001).
Conclusion: aerobic training can have a positive effect on the heart tissue in diabetic rats by reducing oxidative stress.
Physical Education
Mehdi Zarei; Rahim Golmohammadi; Elham Iziy; Seyed Mehdi Beheshti Nasr
Volume 28, Issue 2 , May and June 2021, , Pages 165-172
Abstract
Introduction: There has been no report on the effect of epilepsy on liver enzymes and lipoproteins and its changes following exercisetraining in epileptic rats with Pentylenetetrazole. Materials and Methods: In this experimental study, 70 male rats were placed in 7 groups. An intact group, three groups ...
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Introduction: There has been no report on the effect of epilepsy on liver enzymes and lipoproteins and its changes following exercisetraining in epileptic rats with Pentylenetetrazole. Materials and Methods: In this experimental study, 70 male rats were placed in 7 groups. An intact group, three groups of Kindle and three groups of non-Kindle who received PTZ or normal saline injections every 48 hours until the animals were kindled. 24 hours after Kindling, blood samples were collected in intact group and two groups of Kindle and non-Kindle. One Kindle group and one non-Kindle group from the remaining four groups performed aerobic exercise for six weeks, and the other two groups were inactive for six weeks. Blood were collected 24 hours after the 6-week period, and were compared with control groups. Results: After 4 weeks of Kindling period, total cholesterol, triglycerides, low-density lipoprotein, liver enzymes (P <0.001) and antigenic coefficient (P <0.01) increased significantly in the epileptic group. After six weeks of aerobic exercise in Kindle animals; Triglycerides (P <0.001), liver enzymes (P <0.01) and antigenic coefficients significantly reduced, and high-density lipoprotein significantly increased (P <0.01). Conclusion: The results showed that aerobic exercise in epileptic rats with Pentylenetetrazole improved lipid profile impairement and increased liver enzymes caused by epilepsy.
Physiology & Pharmacology
Masoumeh habibian; Saied Amirnia Shobi; Emamali Zakeri Khatir
Volume 28, Issue 1 , January and February 2021, , Pages 134-142
Abstract
Introduction: Childhood obesity is associated with an increased risk for several metabolic and cardiovascular complications, and is now considered as a state of chronic low-grade inflammation. The aim of this study was to invistigate of the effect 8 weeks of regular aerobic exercise on the Tumor necrosis ...
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Introduction: Childhood obesity is associated with an increased risk for several metabolic and cardiovascular complications, and is now considered as a state of chronic low-grade inflammation. The aim of this study was to invistigate of the effect 8 weeks of regular aerobic exercise on the Tumor necrosis factor alpha (TNF-α) and lipid profile in obese girls. Materials and Methods: This semi experimental research, 14 obese girls (mean age 9.9±1.18 year) whose body mass index was 95% or greater were selected and assigned randomly to two equal groups as follow: exercise and control groups. Aerobic exercise was consisted of exercise movements at 50% to 70% maximal heart rate and 3 sessions/week for 8 weeks. Fasting blood samples were collected before and 48 hour after the last intervention. The serum levels of TNF-α, triglycerides, total cholesterol, lowdensity lipoprotein cholesterol (LDLC) and high density lipoprotein cholesterol (HDL-C) were measured. Data were analyzed by paired and independent t tests. The level of statistical significance was set at p < 0.05. Results: Eight weeks of aerobic exercise caused a significant decrease in TNF-α, triglycerides, total cholesterol, LDL-C and an increase in HDL-C levels (p < 0.05). Compared with the control group, the percent changes of these variabls in exercise training group were significantly greater (p < 0.05). Conclusion: Aerobic exercise as a non-medical therapeutic intervention for obese children can leads to reduced cardiovascular and metabolic diseases risk factors by improving lipid profiles and a reducse in systemic inflammation. Received
Physical Education
Ladan Hosseini Abrishami; Seyed Mahmud Hejazi; Amir Rashid Lamir
Volume 27, Issue 5 , November and December 2020, , Pages 710-718
Abstract
Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials ...
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Introduction: Adhesive molecules are cellular markers that identify the process of atherosclerotic plaque formation in the endothelial wall of arteries. The aim was evaluation of changes in E-selectin and P-selectin in men with heart failure after eight weeks of continuous and intermittent aerobic exercise.
Materials and Methods: 42 men with heart failure were selected by sampling method as volunteers and were divided into three equal groups (14 subjects) continuous aerobic, intermittent aerobic exercises and control groups. Continuous training (45-70% of Maximum Heart Rate) and intermittent training (45-80% of MHR with 5-10 minutes rest between each period) were done for 8 weeks (three days a week). Fasting blood samples were taken from all subjects before and after eight weeks of aerobic exercise and adhesion molecules were measured by ELISA method. Data were analyzed by ANCOVA at significance levels of P<0.05.
Results: Comparison of the groups with covariance analysis showed that the levels of E-selectin (P=0.002) and P-selectin (P=0.022) levels was significant in all three groups. The Bonferroni test showed, There was a significant difference between the intermittent and control (P=0.005) and between continuous and control groups (P=0.006) at the level of Eselectin and the intermittent aerobic and control groups (P=0.032) at Pselectin level, However, there was no significant change despite a decrease between the control and continuing aerobic (P=0.083) in Pselecteine. Also, there was no significant difference in the studied variables in both intermittent and continuous aerobic groups.
Conclusion: Aerobic exercise with reducing levels of adhesion molecules may play an important role in the prevention and control of cardiovascular diseases in men with heart failure.
Physical Education
Saber Saed-Mocheshi; Marziyeh Saghebjoo; Zakaria Vahabzadeh; Dariush Sheikholeslami Vatani
Volume 27, Issue 3 , September and October 2020, , Pages 394-401
Abstract
Background and Objectives: Lifestyle modification is an important aspect of preventing various diseases, including various types of cancer. The aim of the present study was to investigate the effect of eight weeks of aerobic training and green tea extract on NF-κB, COX-2 and suppressor protein ...
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Background and Objectives: Lifestyle modification is an important aspect of preventing various diseases, including various types of cancer. The aim of the present study was to investigate the effect of eight weeks of aerobic training and green tea extract on NF-κB, COX-2 and suppressor protein of p53 in prostate tissue of healthy rats.Materials & Methods: 32 male Wistar rats were randomly divided into four groups: green tea extract, exercise training, green tea extract + exercise training, and control. The exercise training program included aerobic training on a low to moderate intensity on the treadmill (at a speed of 3-10 m/s, 3 sets of 15 min with 2 min of rest between sets, 5 days a week). Green tea extract was gavaged at a dose of 1.3 ml of solution at a concentration of 10 mg/100 ml (3 sessions per week). Scarify was performed 48 hours after the end of the intervention. The results were analyzed using parametric statistical methods of analysis of covariance and one way ANOVA.Results: Aerobic training significantly increased NF-κB level compared to the control group (P = 0.02). The combination of aerobic training and consumption of green tea extract did not significantly change the level of NF-κB. The COX-2 and p53 levels were not significantly different after aerobic training and green tea extract (P > 0.05).Conclusion: Green tea supplementation seems to modulate NF-κB level following aerobic training, which can reflect the anti-inflammatory effects of green tea and its role in preventing prostate cancer.
Physical Education
Fatemeh Rostami; Ramin Shabani
Volume 26, Issue 2 , July and August 2019, , Pages 185-193
Abstract
Background: It seems that exercise training can be effective in improving glucose homeostasis and blood lipids by inducing circulating level of irisin. Therefore, the purpose of this study was to evaluate the effect of eight week aerobic training on serum irisin, blood lipid and blood sugar in untrained ...
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Background: It seems that exercise training can be effective in improving glucose homeostasis and blood lipids by inducing circulating level of irisin. Therefore, the purpose of this study was to evaluate the effect of eight week aerobic training on serum irisin, blood lipid and blood sugar in untrained women. Materials and Methods: This semi- experimental study was conducted on 20 sedentary volunteer women among a university of Rasht city in two groups. The control group conducted the routine daily activities, but the experimental group participated in 65 min aerobic training, three times a week for eight consecutive weeks. Blood lipids, glucose homeostasis and circulating irisin were assessed at baseline, and after 8 weeks of interventions. Data were analyses using SPSS version 22 and A P-value of P< 0.05 was considered statistically significant.Results: In the training group, insulin (p=0.02) and HOMA (p=0.04) were decreased and HDL-C (p=0.00) was increased following 8-weeks of intervention. However, there were no significant changes in fasting blood sugar, triglyceride, cholesterol, LDL-C and irisin (P>0.05). In the control group, fasting blood sugar (p=0.04), insulin (p=0.01), HOMA (p=0.00), triglyceride (p=0.03) and irisin (p=0.03) were increased following 8-weeks of study period. After intervention, participants undergoing exercise training had significantly lower cholesterol (p=0.00), triglyceride (p=0.02), insulin (p=0.00) and HOMA (P=0.00) and higher HDL-C (p=0.00) compared with the control group.Conclusion: It seems that aerobic training in sedentary women is associated with an improvement in glucose homeostasis and HDL-C independently of the irisin changes.
Anatomy, Histologyو Embryology
Behrooz Yahyaei; Mahnaz Nouri; Maedeh Ramezani
Volume 25, Issue 6 , November and December 2018, , Pages 885-894
Abstract
Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice ...
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Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice Wistar rat. 49 rats into 7 groups: control (n=7), sham (n=7), no practice at a dose of 2mg/kg Boldenone (n=7), without practicing at a dose of 5mg/kg Boldenone (n=7), group exercise (n=7), a workout at a dose of 2mg / kg dose Boldenone (n=7) and practice 5mg/kg Boldenone (n=7) were divided. The mice were kept under identical conditions and with the same power and endurance activities according to their protocol and drug Boldenone the intervention groups were injected. After eight weeks, the mice were anesthetized and sacrificed them tissue samples from the cerebellum were prepared.Results: There was a significant difference between the groups treated with exercise and control group without exercise. In the group exercise amount and rate of change of the cerebellum tissue is significantly lower than the control group. And even there was a significant difference between the two groups with different dosages also under endurance exercise.Conclusion: The results showed that endurance and aerobic activity for 8 weeks can be largely Boldenone effects of the drug on mice reduces brain tissue but with increasing doses Boldenone creation these changes are inevitable.
Nahid Bijeh; fahime sadat jamali; fateme nejati; mahbobe lotfalizade
Volume 25, Issue 5 , November and December 2018, , Pages 706-714
Abstract
Background: Obesity in patients is followed by decreased kidney function and leads to renal damage in healthy people. The aim of this study was to investigate the effect of aerobic exercise with and without green tea consumption on kidney function in sedentary postmenopausal women.Materials and Methods: ...
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Background: Obesity in patients is followed by decreased kidney function and leads to renal damage in healthy people. The aim of this study was to investigate the effect of aerobic exercise with and without green tea consumption on kidney function in sedentary postmenopausal women.Materials and Methods: Out of 60 volunteers, 29 sedentary postmenopausal women with a body mass index higher than 25 kg/m2 were randomly divided into three groups, exercise, supplement and exercise+supplement. Aerobic exercise program was performed for 8 weeks, 3 sessions per week and each session for 45 minutes at 65-75 % of maximum heart rate. Supplement groups consumed 6 g of green tea powder in 600 ml of almost boiling water (80 °) daily and one hour before their meals for 8 weeks. Combined group performed exercise and consumed supplement, simultaneously.Results: In supplement group, creatinine levels (p=0.048) decreased significantly; While none of the variables in exercise group (uric acid (p=0.432), urea (p=0.681) and creatinine (p=1)) and exercise+supplement group (uric acid (p=0.597), urea (p=0.270) and creatinine (p=0.235)) had no significant change. Between groups changes in any of the variables was not significant too.Conclusion: Eight weeks of aerobic exercises in water alone and in combination with green tea consumption did not improve renal function in obese and overweight postmenopausal women, while green tea consumption alone decreased serum creatinine and improved renal function.
Physical Education
Rambod Khajei; 1. Amir Hossein Haghighi; mohamad reza hamedinia; amir rashid lamir
Volume 25, Issue 4 , September and October 2018, , Pages 507-517
Abstract
Background: Aerobic exercise is the most popular sport activity in cardiac rehab center for increase aerobic ability and decrease in fat mass of cardiovascular disease , the aim of this study was to investigate the effect of eight weeks aerobic exercise on LXR gene expression and lipid profile in middle ...
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Background: Aerobic exercise is the most popular sport activity in cardiac rehab center for increase aerobic ability and decrease in fat mass of cardiovascular disease , the aim of this study was to investigate the effect of eight weeks aerobic exercise on LXR gene expression and lipid profile in middle aged men after CABG.Materials and Methods: The subjects were 20 CABG middle aged male patient were randomly assigned into two group : control (N=10), and aerobic training (n = 10) groups. Exercise group performed aerobic exercises for 8 weeks with an intensity 60% to 80% of heart rate. 48 hours before exercise and 48 hours after the last training session, all subjects blood samples were taken and plasma and monocyte isolation were performed to measure the indices. Data analysis were performed by using t-test and independent t-test, and non-parametric Mann-Whitney and Wilcoxon tests were performed at a significant level of p≤0.05.Results: Significant increase in expression of LXR gene value and HDL and significant decrease in total cholestrole, apo A and B ratio, LDL,TGS in experimental group compared to the control group compared to the control group has seen.Conclusion: Improvement of lipid profiles levels and enhancing the expression of LXR gene after 8 weeks of aerobic exercises showed that Performing regular aerobic exercises as part of the cardiac rehabilitation can be effective in reducing the incidence of atherosclerosis and preventing recurrence of the patient.
Physical Education
Parvin Farzanegi; Mirabdollah Tahramozi
Volume 25, Issue 3 , July and August 2018, , Pages 327-333
Abstract
Background and aim: Chronic kidney disease as an important risk factor associated with some disorders including hypertension and heart failure which is the major cause of death and disability in older people. Hence, the aim of the present study was to investigate the effects of two types aerobic exercise ...
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Background and aim: Chronic kidney disease as an important risk factor associated with some disorders including hypertension and heart failure which is the major cause of death and disability in older people. Hence, the aim of the present study was to investigate the effects of two types aerobic exercise on levels of apelin and its receptor in the old rats heart tissue with chronic kidney disease Methods and Materials: In this experimental study, 28 aged male wistar rats )48 to 50 weeks) were selected and randomly divided into 4 groups: control, doxorubicin, doxorubicin-30minutes training and doxorubicin-60 minutes training. Chronic kidney disease induced by a single subcutaneous injection of doxorubicin (8.5 mg kg). The swimming training program includes 3 times per week, 30 and 60 minutes for 8 weeks. The levels of apelin and its receptor in heart tissue measured by using ELISA method. one-way analysis of variance was used to analyze the data)p
Mahmood Nikseresht
Volume 25, Issue 2 , May and June 2018, , Pages 205-215
Abstract
Background: Regular exercise training has been postulated as an important strategy to reduce inflammatory markers, but it is still not clear what type of training is most appropriate. The purpose of this study was to compare the effects of nonlinear resistance training (NRT) and aerobic interval training ...
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Background: Regular exercise training has been postulated as an important strategy to reduce inflammatory markers, but it is still not clear what type of training is most appropriate. The purpose of this study was to compare the effects of nonlinear resistance training (NRT) and aerobic interval training (AIT) on interleukin-18 (IL-18) and C-reactive protein (CRP) in obese young men. An additional aim was to compare the inflammatory markers between the obese and non-obese men to determine the obesity effect. Materials and Methods: Thirty-eight obese and young men (age=31.4±5.2 year, body fat%=27.3±1.5) were randomly assigned to NRT (n=14), AIT (n=12) and control (CON, n=12) groups. An age-matched control group of non-obese men were also recruited for baseline comparison. Independent t-test and 2-factor repeated measures analysis of variance (ANOVA) were used for analyzing data.Results: No significant differences were noted at baseline between obese and non-obese men for IL-18 (P=0.17), CRP (P=0.77) and VO2peak (P=0.24). After training, VO2peak increased in NRT (P=0.03) and AIT (P=0.001) compared to the CON, but in AIT more than in NRT (P=0.02). Compared to the CON, both of training were equally effective at reducing fat mass (P=0.001). However, there were no significantly changes in IL-18 (P = 0.26) and CRP (P=0.15) after training. Conclusion: Lack of significant differences for IL-18 and CRP between obese and non-obese men might be due to the similar status in age and aerobic fitness. It seems that 2 exercise programs could not make a significant reduction in the concentrations of inflammatory markers.
Physical Education
Rambod Khajei; Amir Hossein Haghighi; Mohammad Reza Hamedinia; Amir Rashid Lamir
Volume 24, Issue 1 , March and April 2017, , Pages 79-88
Abstract
Background & Objectives: Cardiac rehabilitation is the most important proceeding to reduce the effects of heart surgery and its effects on cardiovascular disease. Exercise training because of low cost and being attractive can be a motivation for patients with cardiac rehabilitation programs.Exercise ...
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Background & Objectives: Cardiac rehabilitation is the most important proceeding to reduce the effects of heart surgery and its effects on cardiovascular disease. Exercise training because of low cost and being attractive can be a motivation for patients with cardiac rehabilitation programs.Exercise has influence on blood cellular components, especially the number of white blood cells, metabolism, metabolites, peptides and different type of gene expression.The aim of this study was to examine the effect of aerobic training on monocytes gene expression ABCG5 in middle-aged men after heart bypass surgery. Materials & Methods: In this semi-experimental study, 20 middle-aged malepatient who had coronary artery bypass surgery, were subjected to the study and were randomly assigned into two groups: control (N=10) and aerobic training (N = 10) groups. Blood samples were taken from subjects before and after training sessions.Monocytes isolated by centrifugation and m-RNA purified by Real-Time PCR was performed.Data were analyzed by ANOVA with repeated measures (SPSS version 16). Results: Results showed that, as a result of exercise training, there was significant increase in mRNA expression of gene ABCG5 in the experimental group than control group. Conclusion: It seems that exercise training as part of the cardiac rehabilitation in patients undergoing coronary artery bypass grafting can improve the reverse cholesterol transport process in the patients by impressing the expression of genes involved in lipid metabolism.
Fatah Moradi; Soran Heidari; Akbar Pejhan
Volume 23, Issue 4 , September and October 2016, , Pages 714-723
Abstract
Background Physical inactivity and obesity have been directly associated with elevated inflammatory markers involving in atherosclerosis, coronary artery disease, and Type II diabetes. The purpose of this study was to survey the effect of 12-week aerobic training on serum levels of interleukin-18 (IL-18) ...
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Background Physical inactivity and obesity have been directly associated with elevated inflammatory markers involving in atherosclerosis, coronary artery disease, and Type II diabetes. The purpose of this study was to survey the effect of 12-week aerobic training on serum levels of interleukin-18 (IL-18) and high-sensitivity C-reactive protein (hsCRP) in sedentary obese men.Methods & Materials In this clinical trial study, 20 sedentary obese men were randomly placed at two groups: aerobic training (n=10, age: 27.8±3.2 y, body fat percentage: 31.7±3.4, BMI: 32.0±3.5 kg/m2) and control (n=11, age: 26.7±2.6 y, body fat percentage 31.4±3.2, BMI: 32.3±2.8 kg/m2). For all subjects, height, weight, body mass index, body fat percentage, maximal oxygen consumption, serum levels of IL-18, and hsCRP (after 12 h fasting) were assessed prior to and after training. Aerobic training was accomplished for 12 weeks (3 sessions per week, intensity 60%-70% of the reserved heart rate, duration of each session 20-40 min). Data were analyzed by SPSS-16 by performing two-way ANOVA with repeated measures test. Statistical significance was accepted at PResults Twelve weeks aerobic training decreased serum levels of IL-18 and hsCRP in sedentary obese men, while no significant changes were observed in the control group.Conclusion It appears that aerobic training can, via influencing on parameters IL-18 and hsCRP, play an important role in reducing incidence of atherosclerosis, coronary artery disease, and Type II diabetics in sedentary obese men.
Khatereh Kamali; Asieh Abbasi Daloii; Ahmad Abdi; Seyyed Javad Ziaolhagh; Alireza Barari
Volume 22, Issue 5 , November and December 2015, , Pages 823-831
Abstract
Background Objectives: The aim of the present study was to investigate the possible effect of 8-week aerobic exercise on undercarboxylated osteocalcin and hs-CRP and insulin resistance in overweight women. Materials & Methods: 20 overweight women (weight 73.19 ± 2.28 kg, age 39.38 ± ...
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Background Objectives: The aim of the present study was to investigate the possible effect of 8-week aerobic exercise on undercarboxylated osteocalcin and hs-CRP and insulin resistance in overweight women. Materials & Methods: 20 overweight women (weight 73.19 ± 2.28 kg, age 39.38 ± 3.66 years old, height 1.61 ± 0.04 cm, and body mass index(BMI) 28.19 ± 4.36 kg/m2) were randomly selected and divided into control and experimental groups. Blood samples from participants were taken 48 hours before pre-test and also after 8 weeks of training. Aerobic exercise was done within 8 weeks – 3 sessions per week with the intensity of 65-70% of reserve heart rate. Data analysis for intragroup and intergroup differences was done using dependent and independent t-test, respectively. A significant difference was observed at pResults: The study yielded that the level of undercarboxylated osteocalcin in experimental group significantly increased (p=0.01) in comparison to that of control group. It was also revealed that, in comparison with control group, the level of hs-CRP (p=0.083) and insulin resistance (p=0.158) in experimental group insignificantly decreased after 8-week training. Conclusions: The eight weeks of regular exercise showed significant increase in undercarboxylated osteocalcin that, with possible impact on beta cells, can be cause improvement in effective factors of resistance insulin such as increased insulin secretion and decreased glucose levels.
Nahid Bijeh; Alireza Delpasand; Keivan Hejazi
Volume 21, Issue 6 , January and February 2015, , Pages 1163-1172
Abstract
Background and Objectives: Aerobic training can be affected in polycystic ovary syndrome (PCOS) which is one of the most common endocrine disorders in women. However, it's worth saying that different intensities of aerobic exercises for curing the disease is in ambiguous. The purpose of this study was ...
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Background and Objectives: Aerobic training can be affected in polycystic ovary syndrome (PCOS) which is one of the most common endocrine disorders in women. However, it's worth saying that different intensities of aerobic exercises for curing the disease is in ambiguous. The purpose of this study was to evaluate the effect of eight weeks aerobic training with different intensities on levels of insulin, fasting glucose and insulin resistance in female rats with polycystic ovary syndrome.
Materials and Methods: In this experimental study, forty adult eight-week rats with Wistar race (185±22 gr) after induction of PCOS, divided into four groups: healthy control, polycystic control, low-and moderate-intensity groups. They took part in eight-week program of aerobic exercise with 45% maximal oxygen consumption (equal 15m/min speed) and 65% maximal oxygen consumption (equal 25m/min speed), within three days a week for two period of 35 minutes with 10 min rest between periods. Data were collected and analyzed by Spss software (version16.0). One way analysis of variance test (ANOVA) was used for comparisons between groups. The level of significance was considered 0.05.
Results: The results showed that there were no significant differences in the level of insulin and glucose in any groups. Insulin resistance in polycystic moderate intensity group compared to control PCOS group had a significant reduction (p=0.035).
Conclusion: According to the results, it seems that aerobic exercise with moderate intensity and with reduction of insulin resistance can be considered as a non-pharmacological treatment method for recovery polycystic ovary syndrome patients.
AmirHossein Haghighi; Hadi YarAhmadi; Maliheh Shojaee
Volume 20, Issue 5 , March and April 2014, , Pages 623-634
Abstract
Abstract
Introduction: Visfatin is a newly discovered adipokine which increases with obesity. It is not clear whether endurance training which induces changes in adipose tissue and blood lipids might decrease the plasma level of visfatin as well. The aim of this study was to investigate the effect of ...
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Abstract
Introduction: Visfatin is a newly discovered adipokine which increases with obesity. It is not clear whether endurance training which induces changes in adipose tissue and blood lipids might decrease the plasma level of visfatin as well. The aim of this study was to investigate the effect of 9 weeks of aerobic training on serum visfatin level and insulin resistance index in obese women.
Materials and methods: Method of research was semiexperimental. Twenty-eight obese female volunteered and were randomly divided into experimental (14 subjects with means of weight 82 ± 10.2 kg, and BMI 34.2 ± 4.3 kg/m2) and control (14 subjects with means of weight 79.9 ± 9.5 kg, and BMI 34 ± 3.9 kg/m2) groups. Aerobic training protocol consisted of 4 sessions per week for 9 weeks. Each training session was a slow running trial at intensity of 65 to 75 percent of maximal heart rate for a period of 15 minutes. To follow the principle of overload, half-a-minute was added to each session after the second week, so that, at the last session the running time reached to 31 minutes. Before and after the training period, blood sampling was performed. Data were analyzed using independent t test and ANCOVA.
Results: Results showed significant reduction of serum visfatin level (p < 0.05), and no significant difference in insulin resistance index, serum HDL, LDL, TC and TG between the control and experimental groups (p > 0.05). In addition, aerobic training reduced significantly body mass index, body weight, waist to hip ratio, body fat percent, and increased significantly maximum oxygen uptake (p < 0.05).
Conclusion: It can be said that 9 weeks of aerobic training can cause significant reduction of serum visfatin and no significant change in insulin resistance index in obese women.