effect of L-carnitine and weight loss diet on Anthropometry indices in women with knee osteoarthritis

Baghban, Farnaz; Hoseinzadie, Mahdie; Mozaffari-Khosravi, Hassan; Dehghan, Ali; Fallahzadeh, Hossein

Document Type : Original Article

Authors

¹ Department of Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

² Department of nutrition, school of public health, Shahid Sadoughi university of medical scienses,Yazd,Iran

³ Department of Internal Medicine, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

⁴ Department of Biostatistics and Epidemiology, Research Center of Prevention and Epidemiology of Non-Communicable Disease, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

Abstract

obesity and diet are the most important risk factors for the development of osteoarthritis. L-carnitine is an anti-oxidant agent and increase energy expenditure. The aim of this study was to evaluate the efficacy of L-carnitine supplementation on the anthropometry measures in obese women with knee osteoarthritis.
Materials and Methods: This study was a randomized clinical trial in which 43 obese women with knee osteoarthritis were randomly assigned into two weight loss diet groups; the first one received the 1000 mg L-carnitine and with the second group took the placebo. Anthropometry indices such as height, weight, Body mass index (BMI), hip and waist circumference were assessed at the baseline and after 12 weeks from the start of intervention. Statistical analyses were carried out using SPSS (version16).
Results: Compared with the baseline, weight, BMI, waist and hip circumference decreased significantly in both groups after 12 weeks of intervention. However, no significant differences were observed between L-carnitine group and placebo group (P>0.05). But mean of changes waist circumference were significant between two groups (P=0.006)
Conclusion: According to the findings, oral administration of 1000 mg L-carnitine could decrease waist circumference but no significant effect observed on other anthropometry indices.

Keywords

Main Subjects

nutrition

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Journal of Sabzevar University of Medical Sciences

effect of L-carnitine and weight loss diet on Anthropometry indices in women with knee osteoarthritis

References

References

Volume 26, Issue 4
November and December 2019
Pages 445-451

effect of L-carnitine and weight loss diet on Anthropometry indices in women with knee osteoarthritis

References

References

Volume 26, Issue 4November and December 2019Pages 445-451

Volume 26, Issue 4
November and December 2019
Pages 445-451