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Abstract

Background and Purpose: Thyroid autoimmune disease is the most common thyroid disorder in low-iodine intake areas; evaluation of thyroid peroxidase antibodies (TPOAb), anti-Thyoglubolin (TGAb) and anti-microsomal (TMAb) in most patients with hypothyroidism is of significant importance. Therefore, the present study was conducted to determine the role of anti-thyroid antibodies in patients with hypothyroidism in Sabzevar, Iran. Methods and Materials: This is a cross-sectional descriptive analytical study where 382 subjects with TSH above normal and T3 and T4 below normal were selected through non-probability convenient sampling. Their TSH, TPOAb, TGAb and TMSb were measured through Eliza method. The obtained data were analyzed in SPSS 15 using chi-square, independent t-test and Pearson correlation coefficient, where P

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