Document Type : Original Article
Authors
1 Student research committee, School of Medicine, Mobini Maternity Hospital, Sabzevar University of Medical Sciences Sabzevar, Iran.
2 Assistant Professor of Infertility & IVF, Department of Obstetrics and Gynecology, School of Medicine, Mobini Maternity Hospital, Sabzevar University of Medical Sciences Sabzevar, Iran.
Abstract
Background: Postoperative pain is the most common postoperative complaint following cesarean section. While gabapentin reduces acute post-cesarean pain, evidence for its efficacy remains limited. This study aimed to investigate the effect of gabapentin in reducing post-cesarean section pain.
Materials and Methods: This randomized, double-blind clinical trial study, was conducted on women scheduled for elective cesarean section under spinal anesthesia at Mobini Hospital. Participants were randomly assigned to receive either a single 300 mg gabapentin capsule (intervention group) or a placebo capsule (control group) administered the drug orally after cesarean section. Postoperative pain intensity was assessed using a Visual Analog Scale (VAS) at 2, 4, 6, 12, and 24 hours postoperatively. Data were analyzed using SPSS version 20, with a significance level set at p < 0.05.
Results: Patients in the gabapentin group reported significantly lower pain scores over the first 24 hours compared to the placebo group (p = 0.043). No significant difference was observed in the requirement for supplemental opioid analgesics between the two groups.
Conclusion: A single preoperative dose of 300 mg gabapentin is effective in reducing acute postoperative pain in patients undergoing elective cesarean section.
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Main Subjects
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