Authors

Abstract

Background and Purpose: Pretreatment with crystalloid has not been able to maintain blood pressure during elective cesarean section under spinal anesthesia and it seems that prophylactic ephedrine+crystalloid can reduce hypotension and administration of high doses of ephedrine. The aim of the present study is to compare the effects of ephedrine+crystalloid pretreatment with crystalloid alone on blood pressure during elective caesarean section under spinal anesthesia. Methods and Materials: In this double blind clinical trial we enrolled 72 women admitted to Ali-ebne-Abitaleb hospital in Zahedan Iran who were candidates for elective caesarean section under spinal anesthesia in 2006and divided them into group A (ephedrine+cistalloid) and group B (placebo+cristalloid) by convenience sampling. Infusion with 10ml/Kg of ringer solution was made within 10-15min before the initiation of spinal block in both groups. Also 10mg ephedrine in group A and placebo in group B were added to the solution. After newborn delivery 20 IU oxitocin and 2mg midazolam were administered to all patients. Systolic BP HR nausea vomiting level of spinal block and neonatal Apgar were recorded and analyzed by Chi-square and student's t-tests (P