Mojtaba Mirseyyedi; Seyyed Reza Attarzadeh hosseini; Ehsan mir; Keivan Hejazi
Volume 21, Issue 2 , May and June 2014, , Pages 283-292
Abstract
Background: The risk of developing diabetes and cardiovascular disease in the elderly, obese and sedentary population is high. Exercise can improve metabolic disorders associated with these diseases. The aim of this study was to investigate the effect of eight weeks resistance exercises on C-reactive ...
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Background: The risk of developing diabetes and cardiovascular disease in the elderly, obese and sedentary population is high. Exercise can improve metabolic disorders associated with these diseases. The aim of this study was to investigate the effect of eight weeks resistance exercises on C-reactive protein (CRP), Interleukin-6 (IL-6) and lipid biomarkers in sedentary middle-aged men.
Materials and Methods: This quasi-experimental study was conducted in 2012 in the city of Sari. In this study, 24 subjects were randomly divided into two groups; experimental and control group (each group 12). The resistance exercise program was performed for eight weeks, 3 times a week, 90 minutes per session, with intensity of 60-70 one repetition maximum. Blood samples were collected before and after the exercise intervention. Data were analyzed using SPSS version 15 and P
Ali Heidarianpour; Ebrahim Zarrin kalam
Volume 20, Issue 1 , March and April 2013, , Pages 34-41
Abstract
Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this ...
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Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this study is effects of resistance exercise on vascular function of C-peptide. Materials and methods: In this experimental study, Male wistar rats (220±10g, N=30) were used in two diabetic (control and trained) and one age-matched healthy control groups. After 1 week of diabetes induction, animals were submitted to resistance exercise training for 9
Weeks on ladder. To characterize cutaneous micro vascular responses by Laser Doppler
flowmetery, animals were deeply anesthetized by intraperitoneal injection of pentobarbital
sodium (50 mg/kg). For data analysis, one-way ANOVA test was used to compare the groups. Statistically significant difference between the minimum acceptable levels is p<0.05
Results: Local microinjection of c-peptide increased coetaneous blood flow in trained and control diabetic rats, however this effect in trained group is higher than control diabetic group rats. Administration of Nw-nitro-L-arginine (nitric oxide synthase inhibitor) before C-peptide reduced significantly C-peptide vascular effects in trained and control diabetic rats. Conclusions: Chronic resistance exercise potentiate C-peptide vascular function, possibly by nitric oxide pathway
Mohammad Reza Hamedinia; Teyyebh Amiri Parsa; Marziyeh Saadat Azarnive; Seyyed Ali Reza Hosseini Kakhk
Volume 18, Issue 3 , September and October 2011, , Pages 188-197
Abstract
Background and Purpose: Obesity is associated with various metabolic and inflammatory impairments، the effects of which have not been sufficiently studied. Therefore، the purpose of this study was to examine the influence of an 8-week strength training and aerobic training program and a 10-day detraining ...
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Background and Purpose: Obesity is associated with various metabolic and inflammatory impairments، the effects of which have not been sufficiently studied. Therefore، the purpose of this study was to examine the influence of an 8-week strength training and aerobic training program and a 10-day detraining on lipid profile and CRP in obese girls. Methods and Materials: In this experimental study، thirty-six obese female university students were voluntarily recruited and randomly assigned into three groups: control (n=11)، aerobic training or AT (n=12) and strength training or ST (n=13). ST and AT groups trained for 8 weeks، 4 times/week، 60 min/session، with 60 to 70% of 1 repetition maximum for ST، and 65 to 75% of HRmax for AT. Blood samples were taken at baseline، 24 hours after the last exercise session and after 10 days of detraining on fasting state. Data were analyzed in SPSS 16 using repeated measure analysis of variance (RM-ANOVA). The alpha level was established at P0.05). Also، no significant differences were found between the three groups (P>0.05). TC also decreased in AT and ST groups (9% and 19%، respectively); however، the change was not significant (P>0.05). After training no significant changes in HDL، HDL2، HDL3، LDL، and CRP were observed (P>0.05). Ten days of detraining also did not result in any significant alterations in the lipid profile or CRP (P>0.05). Conclusion: Eight weeks of aerobic and strength training have no significant effect on the lipid profile and CRP in obese girls.
Esfandyar Sharifi; Maryam ShahAmir Tabatabayi; Mokhtar Mokhtari
Volume 17, Issue 3 , September and October 2010, , Pages 148-157
Abstract
Background and Purpose: Diabetes Mellitus is the most important metabolic disease which can lead to hyperglycemia and hyperlipidemia. Since herbal medicines are rich in natural antioxidants and are associated with few complications, the effect of the hydroalcoholic extract of Ceratonia siliqua L. seeds ...
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Background and Purpose: Diabetes Mellitus is the most important metabolic disease which can lead to hyperglycemia and hyperlipidemia. Since herbal medicines are rich in natural antioxidants and are associated with few complications, the effect of the hydroalcoholic extract of Ceratonia siliqua L. seeds on the blood glucose and lipids of male diabetic rats were investigated in this study. Methods and Materials: In this experimental study, 56 male mature Wistar rats weighing 210-250 gr were randomly allocated into 7 groups of 8: control group with no treatment, a group daily receiving distilled water, a control group treated with hydroalcoholic extract of Ceratonia siliqua L. seeds (600 mg/kg), a control diabetic group receiving only strptozetocin; and three experimental groups (groups 1, 2, and 3) receiving 600, 300 and 100 mg/kg of oral hydroalcoholic extract of Ceratonia siliqua L. seeds for 16 days respectively, in addition to becoming diabetic by strptozetocin. At the end of experiments, blood samples were prepared from all groups and their blood lipids and sugar were measured. The obtained data were analyzed in SPPS 18 using ANOVA, with P
R VAZIRINEZHAD; GH.H HASANSHAHI; MA SAJADI; A JAFARZADEH; MR MIRZAEI; A TATI
Volume 14, Issue 2 , July and August 2007, , Pages 103-109
Abstract
Background and Purpose: The system and .the Endocrine system are, respectively, to defend the body against infection and to regulate physiologic activities of the body. Experimental as well as clinical evidence support the close interaction and bi-directional communication between the endocrine and immune ...
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Background and Purpose: The system and .the Endocrine system are, respectively, to defend the body against infection and to regulate physiologic activities of the body. Experimental as well as clinical evidence support the close interaction and bi-directional communication between the endocrine and immune systems. Some disorders in immune system were observed in experimental thyroid abnormalities. The aim of this study is to evaluate some immunological factors in hyperthyroid females.
Methods and Materials: In this descriptive study, blood samples were collected from 50 females with hyperthyroid disease and a control group consisting of 50 sex - and age - matched euthyroid subjects. Thyroid function was assessed according to measurent of T3, T4 and TSH levels. The following parameters were studied in both groups: total and differential white blood cell counts determined on stained-blood smear), serum concentration of immunoglobulins including: IgG, IgA, IgM (measured by SRID method) and IgE (quantitated by ELlSA technique), seropositivity rates of CRP (determined by latex agglutination method), C3 and C4 complement components measured by SRID method.
Results: The mean serum concentrations of IgG, IgA, IgM and IgE were 2312.4±584 mg/dl, 296±87 mg/dl, 118.±28 mg/dl and 301±264 IU/ml in hyperthyroid females and were 1539±974 mg/dl, 243± 116 mg/dl, 140.1±68.9 mg/dl and 109.8±115 IU/ml in euthyroid subjects, respectively. Statistical analyses showed that the mean serum levels of IgG, IgA and IgE were significantly higher in hyperthyroid group as compared to euthyroid group. The seropositive rate of CRP was 20% and 4% in hyperthyroid and euthyroid groups, respectively. The seropositive rate of CRP was also significantly higher in hyperthyroid group as compared to euthyroid group. However, IgM, C3 and C4 levels and white blood cell counts were similarly expressed in two groups.
Conclusion: The results indicate that some immunological alterations such as elevation of serum IgG, IgA and IgE levels and higher seropositive rate of CRP occur in hyperthyroid women.
B BARATI; M SHIRAZI; M SAADATI; MJ SOLTANPOUR
Volume 14, Issue 2 , July and August 2007, , Pages 117-127
Abstract
Background and purpose: Staphylococcus aureus is a pathogen which can cause food poisoning, under certain conditions though growth in nutrients and producing enterotoxin. Only some strains are capable of producing enterotoxin and causing food poisoning and their presence can be detected by DNA amplification ...
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Background and purpose: Staphylococcus aureus is a pathogen which can cause food poisoning, under certain conditions though growth in nutrients and producing enterotoxin. Only some strains are capable of producing enterotoxin and causing food poisoning and their presence can be detected by DNA amplification and gene sequence specification. Therefore, this research was conducted to detect type e enterotoxin producing staphylococcus aureus.
Methods and Materials: 95 staphylococcus aureus strains were isolated from 150 nasal carriers using sterilized swabs and were confirmed by biochemical tests. Then primers were designed and the PCR was used to amplify amplify the staphylococcal enterotoxin e gene (sec) in order to detect type C enterotoxogenic strains.
Results: DNA amplification fragments of 397 bp for staphylococcal nuclease and those of 271 bp for type e gene were confirmed by enzymatic digestion. Only 9.5% of the isolated strains contained sec gene. Specificity and sensitivity were also evaluated and its sensitivity was found to be 125 cells.
Conclusion: this technique is a rapid, sensitive, specific, inexpensive and different alternative to conventional biochemical and serologic assays and it can be used to detect the agent producing type C staphylococcal enterotoxin.
M SAMAVATI
Volume 12, Issue 1 , March and April 2005, , Pages 6-10
Abstract
Background and Purpose: This study is intended to evaluate the results of intraoperative Mitomycin- C application in external D.C.R surgery compared with same results without Mitomycin-C application.
Methods and Materials: In this prospective randomized controlled study, a total of 66 eyes diagnosed ...
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Background and Purpose: This study is intended to evaluate the results of intraoperative Mitomycin- C application in external D.C.R surgery compared with same results without Mitomycin-C application.
Methods and Materials: In this prospective randomized controlled study, a total of 66 eyes diagnosed with acquired Nasolacrimal duct obstruction were randomly divided into a simple external D.C.R group and a Mitomycin-C group in which Mitomycin-C was used during surgery. The surgical procedures in both groups were exactly the same, except that in Mitomycin-C group, a piece of cotton soaked with 0.2 mg/ml Mitomycin-C was applied to osteotomy site for 20 minutes. The symptoms and signs of the two groups in a 7-month follow-up were evaluated.
Results: In the simple D.C.R group, 75.8% of the patients remained Epiphora free after 7 months of follow-up; while in the Mitomycin-C group, 94% of patients were reported to be Epiphora-free. There was a significant difference between the two groups: the potency rate in simple group in 72.7% compared with 94% in the Mitomycin-C group. In the simple group, 69.7% having a normal tear Meniscus level compared with 91% in Mitomycin-C group. There were no severe complications except for one patient with delayed epistaxies and two patients with delayed wound healing in Mitomycin-C group.
Conclusion: Intraoperative Mitomycin-C application is effective in increasing the success rate of D.C.R surgery and no significant complication results from its use.