Biophysics & Radiotherapy
Mehrdad Yadegari; Amin Bigham-Sadegh; Ali Saberi; Ali Parvizi; Elham Moghtadaiee-Khorasgani
Volume 27, Issue 3 , September and October 2020, , Pages 483-491
Abstract
Introduction:Tendon rupture is one of the most common problems in livestock and human. Tendon has a special blood flow network that is fed from outside to inside. The most important factor in tendon healing is blood flow which is very slow. Various methods that have been implemented to treat and repair ...
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Introduction:Tendon rupture is one of the most common problems in livestock and human. Tendon has a special blood flow network that is fed from outside to inside. The most important factor in tendon healing is blood flow which is very slow. Various methods that have been implemented to treat and repair these raptures are time-consuming.
Materials and Methods: 10 male New Zealand rabbits with weight 1-2/5 kg were selected and kept for one month. The posterior organs of the rabbits were shaved and anesthetized. Then, under sterile conditions, the SDFT tendon was cut through the skin, the rabbits were divided into two groups of five and the control group and received three groups of samples at a dose of 1μg/kg of Theranekron, and during the days of 3, 10 And 30 ultrasound examinations. After 30 days, the samples were euthanasia for pathological investigations, and the lesion was removed and sent to the lab.
Results: The results of the thirtieth day of ultrasound examination showed a significant improvement in the tendon fibroblasts, similar to the normal area of the damaged region of echogenicity. Histopathologic results show the beneficial effects of Theranekron during this study. Therefore, the number of collagen fibers accumulated in the tissue in the treated group significantly increased.
Conclusion: It was concluded that Theranekron was effective in healing tendons and reducing inflammation.
Anatomy, Histologyو Embryology
Behrooz Yahyaei; Mahnaz Nouri; Maedeh Ramezani
Volume 25, Issue 6 , November and December 2018, , Pages 885-894
Abstract
Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice ...
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Introduction:Today the anabolic steroids, widely used but side effects aren’t wellknown, this research aimed to study the effects of anabolic steroids Bulednon with aerobic training on cerebellar tissue changes of male Wistar rat have been made during 2016.Methods: This study was conducted on mice Wistar rat. 49 rats into 7 groups: control (n=7), sham (n=7), no practice at a dose of 2mg/kg Boldenone (n=7), without practicing at a dose of 5mg/kg Boldenone (n=7), group exercise (n=7), a workout at a dose of 2mg / kg dose Boldenone (n=7) and practice 5mg/kg Boldenone (n=7) were divided. The mice were kept under identical conditions and with the same power and endurance activities according to their protocol and drug Boldenone the intervention groups were injected. After eight weeks, the mice were anesthetized and sacrificed them tissue samples from the cerebellum were prepared.Results: There was a significant difference between the groups treated with exercise and control group without exercise. In the group exercise amount and rate of change of the cerebellum tissue is significantly lower than the control group. And even there was a significant difference between the two groups with different dosages also under endurance exercise.Conclusion: The results showed that endurance and aerobic activity for 8 weeks can be largely Boldenone effects of the drug on mice reduces brain tissue but with increasing doses Boldenone creation these changes are inevitable.