Gyneocology
Hadis Sourinejad; Mitra Savabi Esfahani; Mohannad Javad Tarrahi; Elham Adib moghaddam
Volume 28, Issue 3 , May and June 2021, , Pages 359-371
Abstract
Introduction: Polycystic ovary syndrome (PCOS)is the most common endocrine disorder in women of childbearing age.There are many challenges regarding the quality of oocytes in these individuals.Therefore, this review study aimed to investigate the consequences and challenges associated with in vitro fertilization ...
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Introduction: Polycystic ovary syndrome (PCOS)is the most common endocrine disorder in women of childbearing age.There are many challenges regarding the quality of oocytes in these individuals.Therefore, this review study aimed to investigate the consequences and challenges associated with in vitro fertilization in women with polycystic ovary syndrome.
Materials and Methods: For related studies, the Persian SID and Magiran databases and Pubmed, Scopus, Elsevier, Weily online library, Sciences Web of Science databases and Google Scholar search engine were used for the period 1990–2019. To obtain all articles in Persian and English,the keywords of Polycystic ovarian syndrome, in vitro fertilization, Polycystic ovarian morphology, IVF outcome,Oocyte donation,Oocyte competence,Pregnancy,and their Persian equivalent are used separately or as possible combinations. From 450 articles, 17 were eligible and selected for this study.
Results: The results of various studies suggesting major challenges in this group of women including gonadotropins need and hormone-related changes, ovarian hyperstimulation syndrome (OHSS), clinical pregnancy rates, pregnancy outcomes and the risk of miscarriage, the quality of oocytes in women with polycystic ovary syndrome undergoing in vitro fertilization and the issue of egg donation in this group of women. However, fetal loss, clinical pregnancy and live birth rates are no different from other women.
Conclusion: Due to concerns about pregnancy in women with PCOS, closer monitoring of these pregnancies is important, it also appears that the presence of PCOS in donors does not affect the rate of pregnancy or implantation and the number of embryos transferred in ovarian donation programs. As a result, women with PCOS should not be excluded from egg donation programs.
Gyneocology
Farzaneh Montazerifar; Marzieh Ghasemi; Rasul Taghvaee far; Mahdieh Keykhahnejad; Mansour Karajibani; Ebrahim Alijani
Volume 28, Issue 2 , May and June 2021, , Pages 294-301
Abstract
Introduction: Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders in women of infertility. Women with PCOS are at high risk for early cardiovascular disease. The aim of this study was to evaluate the oxidative stress, inflammatory factors and other cardiovascular risk factors ...
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Introduction: Polycystic ovary syndrome (PCOS) is one of the most common hormonal disorders in women of infertility. Women with PCOS are at high risk for early cardiovascular disease. The aim of this study was to evaluate the oxidative stress, inflammatory factors and other cardiovascular risk factors in patients with PCOS. Materials and methods: In this case-control study, 50 women with PCOS and 50 healthy women referred to Zahedan Infertility Clinic who were matched for age and BMI were selected by convenient sampling method. Anthropometric parameters, biochemical tests, C3 and C4 complements, TAC and MDA levels were measured in all subjects. Data were analyzed using independent t-test and analysis of variance at the significant level P Results: Results showed that mean waist circumference (P = 0.048), systolic blood pressure (P <0.01) and diastolic (P = 0.048), serum LDLC levels (P = 0.05) and MDA (P <0.0001) were significantly higher in women with PCOS and serum HDL-C levels (P = 0.03) and TAC (P = 0.05) were significantly lower than control group. Mean serum levels of C3 and C4 were higher in the PCOS group than in the control group, but this difference was only significant for C3 (P = 0.03) . Conclusion: The findings showed that levels of dyslipidemia, oxidative stress and inflammatory factors were higher in PCOS women with abdominal obesity. Thus, screening of these factors and weight management, especially in obese women with polycystic ovary syndrome, is recommended in treatment strategy.
Nahid Bijeh; Alireza Delpasand; Keivan Hejazi
Volume 21, Issue 6 , January and February 2015, , Pages 1163-1172
Abstract
Background and Objectives: Aerobic training can be affected in polycystic ovary syndrome (PCOS) which is one of the most common endocrine disorders in women. However, it's worth saying that different intensities of aerobic exercises for curing the disease is in ambiguous. The purpose of this study was ...
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Background and Objectives: Aerobic training can be affected in polycystic ovary syndrome (PCOS) which is one of the most common endocrine disorders in women. However, it's worth saying that different intensities of aerobic exercises for curing the disease is in ambiguous. The purpose of this study was to evaluate the effect of eight weeks aerobic training with different intensities on levels of insulin, fasting glucose and insulin resistance in female rats with polycystic ovary syndrome.
Materials and Methods: In this experimental study, forty adult eight-week rats with Wistar race (185±22 gr) after induction of PCOS, divided into four groups: healthy control, polycystic control, low-and moderate-intensity groups. They took part in eight-week program of aerobic exercise with 45% maximal oxygen consumption (equal 15m/min speed) and 65% maximal oxygen consumption (equal 25m/min speed), within three days a week for two period of 35 minutes with 10 min rest between periods. Data were collected and analyzed by Spss software (version16.0). One way analysis of variance test (ANOVA) was used for comparisons between groups. The level of significance was considered 0.05.
Results: The results showed that there were no significant differences in the level of insulin and glucose in any groups. Insulin resistance in polycystic moderate intensity group compared to control PCOS group had a significant reduction (p=0.035).
Conclusion: According to the results, it seems that aerobic exercise with moderate intensity and with reduction of insulin resistance can be considered as a non-pharmacological treatment method for recovery polycystic ovary syndrome patients.