Mojtaba Mirseyyedi; Seyyed Reza Attarzadeh hosseini; Ehsan mir; Keivan Hejazi
Volume 21, Issue 2 , May and June 2014, , Pages 283-292
Abstract
Background: The risk of developing diabetes and cardiovascular disease in the elderly, obese and sedentary population is high. Exercise can improve metabolic disorders associated with these diseases. The aim of this study was to investigate the effect of eight weeks resistance exercises on C-reactive ...
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Background: The risk of developing diabetes and cardiovascular disease in the elderly, obese and sedentary population is high. Exercise can improve metabolic disorders associated with these diseases. The aim of this study was to investigate the effect of eight weeks resistance exercises on C-reactive protein (CRP), Interleukin-6 (IL-6) and lipid biomarkers in sedentary middle-aged men.
Materials and Methods: This quasi-experimental study was conducted in 2012 in the city of Sari. In this study, 24 subjects were randomly divided into two groups; experimental and control group (each group 12). The resistance exercise program was performed for eight weeks, 3 times a week, 90 minutes per session, with intensity of 60-70 one repetition maximum. Blood samples were collected before and after the exercise intervention. Data were analyzed using SPSS version 15 and P
Mohammad Reza Hamedinia; Teyyebh Amiri Parsa; Marziyeh Saadat Azarnive; Seyyed Ali Reza Hosseini Kakhk
Volume 18, Issue 3 , September and October 2011, , Pages 188-197
Abstract
Background and Purpose: Obesity is associated with various metabolic and inflammatory impairments، the effects of which have not been sufficiently studied. Therefore، the purpose of this study was to examine the influence of an 8-week strength training and aerobic training program and a 10-day detraining ...
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Background and Purpose: Obesity is associated with various metabolic and inflammatory impairments، the effects of which have not been sufficiently studied. Therefore، the purpose of this study was to examine the influence of an 8-week strength training and aerobic training program and a 10-day detraining on lipid profile and CRP in obese girls. Methods and Materials: In this experimental study، thirty-six obese female university students were voluntarily recruited and randomly assigned into three groups: control (n=11)، aerobic training or AT (n=12) and strength training or ST (n=13). ST and AT groups trained for 8 weeks، 4 times/week، 60 min/session، with 60 to 70% of 1 repetition maximum for ST، and 65 to 75% of HRmax for AT. Blood samples were taken at baseline، 24 hours after the last exercise session and after 10 days of detraining on fasting state. Data were analyzed in SPSS 16 using repeated measure analysis of variance (RM-ANOVA). The alpha level was established at P0.05). Also، no significant differences were found between the three groups (P>0.05). TC also decreased in AT and ST groups (9% and 19%، respectively); however، the change was not significant (P>0.05). After training no significant changes in HDL، HDL2، HDL3، LDL، and CRP were observed (P>0.05). Ten days of detraining also did not result in any significant alterations in the lipid profile or CRP (P>0.05). Conclusion: Eight weeks of aerobic and strength training have no significant effect on the lipid profile and CRP in obese girls.
R VAZIRINEZHAD; GH.H HASANSHAHI; MA SAJADI; A JAFARZADEH; MR MIRZAEI; A TATI
Volume 14, Issue 2 , July and August 2007, , Pages 103-109
Abstract
Background and Purpose: The system and .the Endocrine system are, respectively, to defend the body against infection and to regulate physiologic activities of the body. Experimental as well as clinical evidence support the close interaction and bi-directional communication between the endocrine and immune ...
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Background and Purpose: The system and .the Endocrine system are, respectively, to defend the body against infection and to regulate physiologic activities of the body. Experimental as well as clinical evidence support the close interaction and bi-directional communication between the endocrine and immune systems. Some disorders in immune system were observed in experimental thyroid abnormalities. The aim of this study is to evaluate some immunological factors in hyperthyroid females.
Methods and Materials: In this descriptive study, blood samples were collected from 50 females with hyperthyroid disease and a control group consisting of 50 sex - and age - matched euthyroid subjects. Thyroid function was assessed according to measurent of T3, T4 and TSH levels. The following parameters were studied in both groups: total and differential white blood cell counts determined on stained-blood smear), serum concentration of immunoglobulins including: IgG, IgA, IgM (measured by SRID method) and IgE (quantitated by ELlSA technique), seropositivity rates of CRP (determined by latex agglutination method), C3 and C4 complement components measured by SRID method.
Results: The mean serum concentrations of IgG, IgA, IgM and IgE were 2312.4±584 mg/dl, 296±87 mg/dl, 118.±28 mg/dl and 301±264 IU/ml in hyperthyroid females and were 1539±974 mg/dl, 243± 116 mg/dl, 140.1±68.9 mg/dl and 109.8±115 IU/ml in euthyroid subjects, respectively. Statistical analyses showed that the mean serum levels of IgG, IgA and IgE were significantly higher in hyperthyroid group as compared to euthyroid group. The seropositive rate of CRP was 20% and 4% in hyperthyroid and euthyroid groups, respectively. The seropositive rate of CRP was also significantly higher in hyperthyroid group as compared to euthyroid group. However, IgM, C3 and C4 levels and white blood cell counts were similarly expressed in two groups.
Conclusion: The results indicate that some immunological alterations such as elevation of serum IgG, IgA and IgE levels and higher seropositive rate of CRP occur in hyperthyroid women.