Microbiology
Mahdieh Emadi; Javid Taghinejad; Ayda Ghaffarzadeh
Volume 27, Issue 5 , November and December 2020, , Pages 614-619
Abstract
Introduction: COVID-19 is a highly contagious infectious disease caused by a new coronavirus that can be transmitted from person to person through close contact. The aim of the present study is to investigate new information in the field of COVID-19 immunology. Materials and Methods: The present ...
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Introduction: COVID-19 is a highly contagious infectious disease caused by a new coronavirus that can be transmitted from person to person through close contact. The aim of the present study is to investigate new information in the field of COVID-19 immunology. Materials and Methods: The present study uses Google and Google Scholar search engines and articles indexed by reputable international scientific databases including Pub Med, MedLine, and the World Health Organization (WHO). In this study, published articles about COVID-19 and field of immunology were reviewed, and articles that did not have free access (Open Acess) and only access to abstracts were excluded from the study. Results: In total, studies have been suggested that the amount of cytokines such as IL-10, IL-7, IL-2, G-CSF, and TNF-α has been reported at high levels in patients. The ACE2 receptor is the target receptor for the Covid-19 virus, which binds to it after entering the lungs then IFN-I inhibit the primary replication and inhibition of the virus. Conclusion: After reviewing the articles, it was found that strengthening the immune system against viral infections is very important. The virus weakens the immune system by disrupting the production of type I interferon and reducing expression in the production of MHC-I, II. One of the best ways to fight COVID-19 is to get the right vaccine to boost immune system and produce T cells and cytokines.
Gyneocology
farzaneh rahimi; shadi goli
Volume 27, Issue 4 , November and December 2020, , Pages 522-531
Abstract
Introduction: Emerging infections have a great impact on the health of pregnant mothers and their fetuses. Due to the importance of contracting this virus during pregnancy and due to the emergence of this virus and the limited number of studies on the consequences of contracting this disease during pregnancy, ...
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Introduction: Emerging infections have a great impact on the health of pregnant mothers and their fetuses. Due to the importance of contracting this virus during pregnancy and due to the emergence of this virus and the limited number of studies on the consequences of contracting this disease during pregnancy, this review study aims to summarize the reported studies on covid-19 infection. Performed during pregnancy and childbirth.
Materials and Methods: In this study, a review of all studies conducted in English on covd-19 in pregnancy and childbirth from 2019 to March 2020, in the databases Scopus, Google Scholar, Pubmed, Science Direct, Cochrane, and keywords covid-19, sars-cov-2, coronavirus-2019, 2019-ncov, pregnancy, delivery.
Results: In these studies, a total of 103 pregnant mothers with covid-19 and their maternal and neonatal outcome and the incidence of infants of mothers with covid-19 were studied. Most of the studies reported in different cities of China were. Pregnant mothers have been examined.
Conclusion: Based on the reported findings, vertical transmission of mother to fetus has not been reported so far and maternal and neonatal outcome have been reported in all well-studied studies, all samples of amniotic fluid, placenta, breast milk and vaginal discharge samples based on studies. COVID-19 was negative and no maternal deaths were reported at the time of this study. Currently, due to the lack of effective treatment and vaccines, the best way to deal with this disease is to avoid infection and prevent its spread through protective measures and personal hygiene.