Sara Jahangiri; Musa Al-Reza Tadayyonfar; Alireza Rahmani; Mohammad Hasan Rakhshani
Abstract
Objectives Constipation is a predominant gastrointestinal problem after the onset of stroke, which may increase intracranial pressure. Treatment of constipation includes using laxatives and fibers, which is associated with complications and limitations. Regarding the effect of probiotics to treat digestive ...
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Objectives Constipation is a predominant gastrointestinal problem after the onset of stroke, which may increase intracranial pressure. Treatment of constipation includes using laxatives and fibers, which is associated with complications and limitations. Regarding the effect of probiotics to treat digestive problems, the current study aimed at investigating the effect of probiotics on constipation in the patients with stroke admitted to Intensive Care Unit (ICU).Methods The current randomized clinical trial was conducted on 65 patients with stroke. Patients with nasal-gastric tube and absence of rejection in 3 consecutive days were enrolled to the study. They were randomly divided into 2 groups of intervention (n=33) and control (n=32); the frequency of their bowel movements were measured before the study. Subjects in the intervention group received a probiotic supplement every 12 hours; however, the ones in the control group received the only routine conventional treatment for a week. After a week, all subjects were assessed for the improvement of constipation. Data were analyzed by SAS software version 9.1 using Poisson regression model. Results In the intervention group, the mean number of bowel movements was more than once a day, 1.22, and in the control group it was 0.62 (P<0.0001).Conclusion The current study showed that probiotic supplement consumption increased the frequency of constipation in patients with stroke. Therefore, probiotics can be used to treat constipation in such patients.
Alireza Pakghalb; Abas Ali Pour Momeni; Roksana Bazaz Behbahani; Gholamreza Raeessi
Volume 22, Issue 2 , May and June 2015, , Pages 453-460
Abstract
Background: Researches has shown that doing the appropriate defecation exercise with biofeedback is the treatment for dyssynergic defecation, but since in many researches it has been indicated that every treatment such as medication, physical therapy & even surgery has a kind of placebo effect on ...
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Background: Researches has shown that doing the appropriate defecation exercise with biofeedback is the treatment for dyssynergic defecation, but since in many researches it has been indicated that every treatment such as medication, physical therapy & even surgery has a kind of placebo effect on patients; therefore, in this study we made a comparison on the effectiveness of therapies between biofeedback and placebo feedback by measuring recovery level of patients suffering from dyssynergic defecation.
Materials and Methods: In this study we implemented clinical trial method in such a way that from totally 42 patients complaining of constipation, 30 patients were selected on the basis of ROMEIII inclusion criteria and were randomly placed in two groups to receive biofeedback & placebo feedback therapies, so that we could measure and compare the ability to defecate the balloon (volume & time) before and after the treatment.
Results: The signs of dyssynergic defecation were improved in both groups in comparison to their pre-therapy time and an advantage was observed in quantitative variables among the patients who received biofeedback therapy. There were significant and positive changes in the criteria of: defecate balloon time& volume in biofeedback group (p