Zahra Jafari; Ryhaneh Toofan; Maryam Aghamollayee; Shadi Rahimzadeh; Mahdieh Esmaeilie
Volume 20, Issue 3 , September and October 2013, , Pages 259-269
Abstract
Background and objective: Hearing loss and tinnitus are two auditory effects of hearing system damage due to occupational noise exposure. These factors can have non-auditory effects by themselves and impact on brain cognitive performance. In our study, the effect of occupational noise-induced hearing ...
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Background and objective: Hearing loss and tinnitus are two auditory effects of hearing system damage due to occupational noise exposure. These factors can have non-auditory effects by themselves and impact on brain cognitive performance. In our study, the effect of occupational noise-induced hearing loss and tinnitus on cognition and auditory-verbal memory was investigated.
Materials and methods: Our study was done on 42 male workers aged 40 to 56 years in three groups of workers with 1) hearing loss, 2) hearing loss and tinnitus and 3) normal hearing. Workers in two first groups had a long history of working in environments with excessive noise, and third group was matched control workers with normal hearing. Hearing impaired persons had symmetrical moderate falling sensory-neural hearing loss in the both ears. For all subjects, Mini-Mental State Examination and Rey Auditory-Verbal Learning Tests were performed in identical conditions.
Results: Normal hearing group had higher scores in all stages of the Rey Auditory-Verbal Learning test than two other groups and their means differences in three A1, Sum and Recognition stages were significant (p≤0.034). Similar finding was observed in the Mini-Mental Examination test too (p≤0.025).
Conclusion: Our study revealed effect of noise induced hearing loss and tinnitus due to prolonged exposure to noise over the limit on general cognition and auditory-verbal memory. Given the preventable nature of auditory and non-auditory effects of occupational noise, administration and control of hearing conservation programs and training of workers can be the suitable and proposed solution.
Mahmoodreza Azarpajooh; Naghmej Mokhber; Negar Asgharipour
Volume 20, Issue 1 , March and April 2013, , Pages 6-14
Abstract
Background: Post stroke depression is a common state after stroke causing disability and affects cognitive status in patients. Present study tried to show the effect of citalopram on post stroke depression as well as cognitive state. Materials and methods: in clinical trial study all patients with ...
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Background: Post stroke depression is a common state after stroke causing disability and affects cognitive status in patients. Present study tried to show the effect of citalopram on post stroke depression as well as cognitive state. Materials and methods: in clinical trial study all patients with acute ischemic stroke who had been consecutively admitted to the Ghaem Hospital (from 1388-1389), in Mashhad were evaluated for inclusion in the study.(218 person).In first visit neurological tests and hamilton rating test for depression were taken. At last 89 patients admitted az sample of study. Cognitive impairment was assessed with the Dementia Rating Scale (DRS). The severity of the depressive symptoms was measured by Hamilton Rating Scale for Depression (HAM-D).Then they were classified into those with severe depressive symptoms (HAM-D >20; N=18), with mild depressive symptoms (HAM-D scores 12-19; N=39) and non-depressed patients (HAM-D scores < 12; N=32). Patients with severe depressive symptoms were treated with citalopram. Statistical analysis was performed using spss version 11.
Results: HRDS, MMSE and DRS scores had significant change at the baseline and the end of study in group treated by citalopram. There were significant differences between DRS scores in attention domain at the baseline and the end of study in both citalopram group and without depression. Conclusion: These data suggest that treatment of depressive symptoms in the acute phase of stroke improves both mood and cognition and would be a reasonable treatment for patients suffering post stroke depression and cognitive change after stroke