Physiology & Pharmacology
Fateme Barfarazi; marzieh kafami; Akbar Pejhan
Abstract
Introduction: High blood pressure is known as the third cause of death in the world. millions of people are affected by this disease. The renin-angiotensin system plays a role in causing this disease. AngiotensinII receptor blockers (AT1) are effective in reducing blood pressure. AngiotensinII expression ...
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Introduction: High blood pressure is known as the third cause of death in the world. millions of people are affected by this disease. The renin-angiotensin system plays a role in causing this disease. AngiotensinII receptor blockers (AT1) are effective in reducing blood pressure. AngiotensinII expression has been observed in the suprachiasmatic nuclei. The aim of this study is to investigate the effect of angiotensinII injection in the suprachiasmatic nucleus on the cardiovascular function of rats.Materials and Methods: 24 male Wistar rats were divided into 3 groups. 1- control, 2- angiotensin II, 3- angiotensinII + losartan. Group1: normal saline with a dose of 100ml, group2: angiotensinII with a dose of 100μm, and group3: angiotensin with a dose of 100μm, and after 30minutes, losartan with a dose of 100μm, and after 2minutes, angiotensin with a dose of 100μm, microinjection into the suprachiasmatic nucleus and blood pressure and heart rate was recorded.Results: There was no significant difference between mean arterial pressure and heart rate before and after saline injection.(P>0.05), in the angiotensin group, ∆MAP and HR∆ compared to before the injection of this dose of angiotensin(P<0.001 and P<0.05), and compared to the control group(P<0.001 and P<0.01), It increased significantly. In the losartan group, microinjection of losartan before the second injection of angiotensinII caused a significant decrease in ∆MAP compared to the first injection of angiotensinII (P<0.001), but it was not significant in HR∆. Conclusion: Microinjection of angiotensinII in the suprachiasmatic nucleus increased blood pressure and heart rate through binding to AT1.
Psychology
Mohammad Tahan; Elahe Ahangari
Volume 27, Issue 5 , November and December 2020, , Pages 656-662
Abstract
Introduction: One of the most severe physiological, psychological disorders and the most critical risk factors for cardiovascular disease is hypertension. High blood pressure is associated with several factors, such as thought control strategies and perceived stress. This study aimed to investigate the ...
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Introduction: One of the most severe physiological, psychological disorders and the most critical risk factors for cardiovascular disease is hypertension. High blood pressure is associated with several factors, such as thought control strategies and perceived stress. This study aimed to investigate the role of thought control strategies on perceived stress in hypertensive patients. Materials and Methods: The research method was a descriptive correlational. To select the research sample, 180 patients with hypertension who referred to the health centers of Qaenat (200 persons in total) were selected in 2018. Participants then responded to Wells and Davis (1994), Perceived Stress Questionnaire Cohen (1983). Data were analyzed by SPSS software version 22. Results: The results showed that there is a significant relationship between the components of mind control, the component of distraction, reassessment, fear and punishment with perceived stress (p <0.05). So that the component of distraction and reassessment of negative relationship and the components of worry and punishment are a positive relationship with perceived stress (p <0.05). Conclusion: Thought control strategies play a role in the perceived stress of hypertensive patients. Stress causes many disorders and mental illness, including hypertension. However, if a person is mentally sound and healthy, he will not be stressed and will be safe from blood pressure.
Physical Education
Nasrin Jahanshiri; nahid bijeh
Volume 27, Issue 2 , July and August 2020, , Pages 173-181
Abstract
Introduction:Menopause is natural phenomenon and it is a stage of a woman's life in which, the menstruation period ends as a result of the reduction of the ovaries activity and the lack of estrogen. Since blood pressure and insulin resistance is a major problem in older women, The purpose of this study ...
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Introduction:Menopause is natural phenomenon and it is a stage of a woman's life in which, the menstruation period ends as a result of the reduction of the ovaries activity and the lack of estrogen. Since blood pressure and insulin resistance is a major problem in older women, The purpose of this study would be studying the The effect of combined training with and without consuming the flaxseed on the Insulin resistance and blood pressure of postmenopausal womenmethods:this quasi-experimental study,27postmenopausal women with the age group of 50 to 60 years old and the BMI equal to 25 to30kg/m2, were selected using the available sampling method. Then they were randomly divided into two groups called the combined training(12people)and the combined training plus flaxseed(15people).The aerobic exercise was preformed with the intensity of 60to80 percent of the maximal heart rate and the resistance exercise with the intensity of60to80 percent of a maximal repetition .complementary was given by using25 gr of the milled flaxseed.The blood samples were collected for measuring insulin resistance and analyzed using SPSS software and Independent and independent t test, respectively, to compare intra-group and inter-group differences at a significant level of P
Mohammad Seyyedahmadi; Akbar Pejhan; Fattah Moradi; Soran Aminiaghaddam
Volume 19, Issue 4 , January and February 2013, , Pages 325-335
Abstract
Background: Adiponectin is the one of adipocytokines, which may be a marker for coronary artery disease and appears to have protective metabolic and anti-inflammatory properties. The purpose of this study was to survey relationships between serum adiponectin levels with insulin resistance, blood pressure, ...
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Background: Adiponectin is the one of adipocytokines, which may be a marker for coronary artery disease and appears to have protective metabolic and anti-inflammatory properties. The purpose of this study was to survey relationships between serum adiponectin levels with insulin resistance, blood pressure, and cardio-respiratory function in sedentary men. Methods and Materials: In semi-experimental study, forty five young men, without experience of regular physical activity during six months ago, were selected. After 12 h fasting (at 8 A.M.), blood samples were collected to determine serum levels of adiponectin, insulin, and glucose. Cardio-respiratory function of subjects was estimated using Balke's treadmill protocol and their blood pressures were measured by sphygmomanometer. Data was analyzed by SPSS 16.0 software and the relationships were calculated by Pearson’s correlation analysis. P value of less than 0.01 was considered statistically significant. Results: Adiponectin levels were negatively correlated to body mass index (r = –0.41, p < 0.002), insulin (r = –0.45, p < 0.009), glucose (r = –0.27, p < 0.007), and HOMA index (r = –0.40, p < 0.002), while positively correlated to maximal oxygen uptake (r = 0.31, p < 0.006). No significant correlations were observed between adiponectin levels and systolic (r = –0.13, p < 0.097) and diastolic blood pressure (r = –0.09, p < 0.117). Conclusions: It appears that in sedentary men, who have lower cardio-respiratory fitness, lower adiponectin levels may be associated with disorder in glycemic, and this promotes probability of diabetes type II and cardiovascular diseases in these subjects. Also, serum concentrations of adiponectin are directly correlated with cardio-respiratory function, but it appears that there is no correlation between adiponectin levels and blood pressure.