Reza Ghotaslou; Tahereh pirzadeh; Aylin Esmailkhani; Abed Zahedi Bialvaie; Hamed Ebrahimzadeh Leylabadlo
Volume 29, Issue 2 , July and August 2022, , Pages 179-194
Abstract
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most effective human pathogens, as over half of the world's population is colonized with this Gram-negative bacterium. Unless treated, colonization usually persists lifelong. H. pylori infection represents a key ...
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Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most effective human pathogens, as over half of the world's population is colonized with this Gram-negative bacterium. Unless treated, colonization usually persists lifelong. H. pylori infection represents a key factor in the etiology of the various gastrointestinal diseases, ranging from chronic active gastritis without clinical symptoms to peptic ulceration, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma (MALT). This review concerns some of the most recent developments in diagnostic methods of H. pylori infection and it has been studied in different clinical conditions. Only highly accurate tests should be used in clinical practice, and the sensitivity and specificity of an adequate test should exceed 90%. The choice of tests should take all items among into account clinical circumstances, the likelihood ratio of positive and negative tests, the cost-effectiveness of the testing strategy, and the availability of the tests.
E NOURIZADEH; K GHASEMI GARMI; SK SHAFAGHIASL; N MALOOFI
Volume 12, Issue 3 , September and October 2005, , Pages 17-21
Abstract
Background and purpose: Today it is obvious that helicobacter pylorus is the most common cause of gastritis the world over. However, this organism plays an important part in the development of gastric ulcer and duodenum ulcer in particular. It is the cause of one of the most common infections in the ...
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Background and purpose: Today it is obvious that helicobacter pylorus is the most common cause of gastritis the world over. However, this organism plays an important part in the development of gastric ulcer and duodenum ulcer in particular. It is the cause of one of the most common infections in the world which involves at least half of the population in most communities. This study is therefore intended to study the antimicrobial effects of water and ethanol extracts of tumeric and cinnamon on five strains of helicobacter pylori.
Methods and Materials: Plants selected to act against five strains of Helicobacter pylori were tumeric and cinnamon, the ethanol and water extracts of which were isolated using the agar diffusion method and examined at Shariatee hospital in Tehran, Iran with gastric and duodenal ulcers, gastritis and gastric cancer. The specimens were transferred to the laboratory on transports.
Results: Among the ethanol and water extracts of the plants, tumeric juices had the highest antibacterial effects; the mean inhibitory growth zone diameter for water and ethanol extracts were 22 and 18mm respectively; while, the same figure for cinnamon were 18 and 12mm respectively.
Conclusion: Cinnamon and tumeric are of antibacterial effects and the antibacterial effect of water extracts of tumeric on helicobacter pylori is remarkable. Therefore, further research is recommended to be conducted on the isolated materials of these herbs.