Microbiology
Kimia Saremi; Zahra Dehghani; Mahmood Vakili; Maryam Sadeh
Abstract
Introduction: Urinary tract infections (UTIs) are prevalent infectious conditions affecting individuals in their youth and middle age. The increased use of broad-spectrum antibiotics and the growing resistance to these drugs emphasize the necessity of understanding bacterial resistance patterns in the ...
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Introduction: Urinary tract infections (UTIs) are prevalent infectious conditions affecting individuals in their youth and middle age. The increased use of broad-spectrum antibiotics and the growing resistance to these drugs emphasize the necessity of understanding bacterial resistance patterns in the context of treatment. This study aimed to identify the resistance patterns of bacteria causing UTIs in patients attending two medical diagnostic and treatment centers in Yazd, Iran.Materials and Methods: Conducted for one year (2018), this descriptive-cross-sectional study involved analyzing 3563 samples of UTI agents collected from the microbiology department of the Central Diagnostic Laboratory and Shahid Sadoughi Hospital in Yazd. Identification of isolated bacteria utilized phenotypic methods, and antibiotic resistance assessments were performed using the disk diffusion method.Results: Among 3563 positive isolates, 80.4% originated from outpatients, while 19.6% were from inpatients. The most prevalent bacteria causing UTIs in both centers were Escherichia coli (57.8%), Klebsiella pneumoniae (9.7%), Staphylococcus aureus (9.1%), Streptococcus agalactiae (7%), and Acinetobacter (0.2%). Escherichia coli isolates exhibited the highest antibiotic resistance, particularly against amoxicillin-clavulanate (62.9%) and nalidixic acid (61.9%). In hospitalized patients, resistance to ampicillin (86%) and cotrimoxazole (72%) was notable, with over half of these isolates displaying ESBL positivity.Conclusion: Given the varying distribution of antibiotic resistance among UTI-causing isolates in both inpatient and outpatient settings, understanding antibiotic resistance patterns in diagnostic-treatment centers across diverse geographical areas is imperative.
Mahmoud Vakili; Moslem Taheri Sodjani; Naser Hossein Sartibzadeh; Sajjad Rahimi Pardanjani; Najibollah Baeradeh; Samira Arjmandizadeh; Leila Ekrami
Volume 22, Issue 1 , March and April 2015, , Pages 114-122
Abstract
Background: Ischemic heart disease is the most important cause of mortality in many places around the world. Premature heart attacks at early ages are increasing, so identifying and controlling risk factors can be an effective step in public health promotion. This study aimed to investigate the factors ...
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Background: Ischemic heart disease is the most important cause of mortality in many places around the world. Premature heart attacks at early ages are increasing, so identifying and controlling risk factors can be an effective step in public health promotion. This study aimed to investigate the factors affecting on this disease.
Methods: This is a case-control study conducted on 100 patients with acute myocardial infarction admitted to the CCU and 100 patients hospitalized in other sectors (as a control) in Shahid Sadooghi hospital, Yazd,Iran . The control group was matched for age, sex and risk factors such as smoking, hyperlipidemia, hypertension, diabetes, depression, stress, eating fast food, fruit and vegetable consumption, positive family history and salty food. Then items were examined. Statistical significant level was considered as 95%.
Results: The results showed that the crude odds ratio for some factors like smoking (OR=2.22 P=.007), greater stress (OR=3.35 P=.000), depression (OR=3.07 P=.001), high triglycerides (OR=1.86 P=.03), high cholesterol (OR= 3.3 P=.000), high LDL (OR=4.88 P=.000) and high HDL (OR=.041 P=.000) is statistically significant, but the adjusted odds ratio determined that only three factors such as depression (OR = 3.09 P.033), high LDL (OR=6.33 P=.004) and high HDL (OR=.021 P=.000 ) have major impact on acute myocardial infarction.
Conclusions: The results of this study indicated that some modifiable factors such as depression, high LDL and high HDL play a role in causing or preventing acute myocardial infarction. Therefore, controlling these factors can be crucial in controlling the disease.
Mahmoud Vakili; Sajjad Rahimi Pardanjani; Narges Alipour; Moslem Taheri; Najibollah Baeradeh; Aliasghar Hashemi
Volume 21, Issue 6 , January and February 2015, , Pages 1214-1224
Abstract
Background and purpose: Gestational diabetes mellitus(GDM) is a metabolic disorder which is diagnosed for the first time during pregnancy. This disease is the most common metabolic disorder in this period. This study was aimed at determining the associated factors with prevalence of in pregnant women ...
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Background and purpose: Gestational diabetes mellitus(GDM) is a metabolic disorder which is diagnosed for the first time during pregnancy. This disease is the most common metabolic disorder in this period. This study was aimed at determining the associated factors with prevalence of in pregnant women in the Yazd city during a specific period of time.
Materials and Methods: This is an analytical descriptive study which has been done by a cross-sectional design. Participants were pregnant women who had been referring to health care centers of Yazd city between April 2012to October2012. 400 pregnant women were selected by cluster random sampling method. Data were collected by a data collection form based on family files and also were analyzed by using SPSS19 Statistical Software. Chi-square, T- test and logistic regression test were used with significant level of 0.05.
Results: The prevalence of GDM in this study was 12% (48 people).Mean age of the patients (29.79±5.86) was significantly higher than normal subjects (26.11±5.11).Diabetic mothers had more number of pregnancies, shorter height, mean weight and body mass indices (BMI)higher than non-diabetic mothers. Significant relationships were found between age, maternal education level, BMI, birth order, family history of diabetes and history of congenital malformations by GDM. (P <0/05).
Conclusions: Due to the higher prevalence rate of GDM in Yazd comparing with other cities performing a general screening study that includes more pregnant women is highly recommended inthis city.