Fatemeh Zihreh; Siam Nasri; Parisa Karishchi
Volume 22, Issue 2 , May and June 2015, , Pages 377-386
Abstract
Background and purpose: Antioxidants such as Quercetin protect sperm cells from free radical damage. This research was conducted to investigate the effects of Quercetin on spermatogenesis in male rats.
Materials and Methods: In this experimental study 50 male rats were used. Quercetin was injected daily ...
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Background and purpose: Antioxidants such as Quercetin protect sperm cells from free radical damage. This research was conducted to investigate the effects of Quercetin on spermatogenesis in male rats.
Materials and Methods: In this experimental study 50 male rats were used. Quercetin was injected daily at doses of 5, 10, 15, 20 (mg/kg) for two weeks intraperitoneally. One week after the last injection, blood samples were collected and the left testis of rats were removed and weighed. Epididymal sperm and testicular sections were also studied. Data were analyzed by using one-way ANOVA at the significant level of 0.05 in SPSS 19 software.
Results: No significant difference was found in serum level of gonadotropins, but testosterone has increased at dose of 20 mg/kg (6.52±0.50, P=0/0079).Significant difference in testicular weight wasn’t seen. The number of sperm (51.35±1.68, P=0.0251) and also sperm mobility (73.88±5.91, P= 0.0002) in the epididymis especially at dose of 20 mg/kg has increased. No significant difference was found between the groups in the number of spermatogonia cells. But the number of primary spermatocytes (118.25±7.04, P=0.0171), spermatids (106.75±6.28, P=0.0032) and Spermatozoa (101.75±6.30, P= 0.0008) were increased at dose of 20 mg/kg.
Conclusion: No significant change in gonadotropins was seen, which indicates that probably Quercetin has not affected PG axis. Quercetin is believed to improve the quality and quantity of germ cells with its antioxidant effects and increasing of testosterone.
MR KHAN MOHAMMADI; M SAMAVI; GH.R HASANZADEH; B RAJABLOO
Volume 12, Issue 1 , March and April 2005, , Pages 11-14
Abstract
Background and Purpose: Determination of the effect of an expensive and non-absorbable element named as gold on spermatogenesis can justify the reason for its being religiously unlawful for men.
Materials and Methods: 36 male Rats were divided into three groups. After the animals were made anesthetized, ...
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Background and Purpose: Determination of the effect of an expensive and non-absorbable element named as gold on spermatogenesis can justify the reason for its being religiously unlawful for men.
Materials and Methods: 36 male Rats were divided into three groups. After the animals were made anesthetized, at the back of neck of group I, a piece of gold measuring 2x1 cm and similarly non-absorbable plastic was attached to the back of neck of second group. Neither a metal nor anything was placed on the third group. Place of cut was sutured. After first and third months, animals were made anesthetised and specimens were taken from testis and were stained with H&E staining and were examined for the structure of seminiferous tubules with the help of image tool-2 software.
Results: There was no significant change in the somniferous tubules or interstitial tissue of all three groups were found.
Conclusion: Probably gold in not unlawful for its organic effect but might be prohibited as an ornamenful object for men.