immunology & Biochemistry
Mohammad Shafi Mojadadi; Nastaran Zakeralhosseini; Azam Khosrogerdi; Mostafa Roshanzadeh; Ali Taj
Abstract
Introduction: The coronavirus epidemic has caused a lot of confusion and tension in the health, economic, and political systems of the world, and its impact on society has led the governments' policy to support the production of drugs and related vaccines, Therefore, this research was conducted to investigate ...
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Introduction: The coronavirus epidemic has caused a lot of confusion and tension in the health, economic, and political systems of the world, and its impact on society has led the governments' policy to support the production of drugs and related vaccines, Therefore, this research was conducted to investigate the findings of vaccination of people infected with covid-19 hospitalized in Vasei Sabzevar Hospital in 2022.
Materials and Methods: This cross-sectional descriptive study was conducted in the year 2022 at Sabzevar city. 3686 people were included in the study by available sampling method. Information was extracted from Sib system using a demographics questionnaire and checklist and analyzed with SPSS 26 software.
Results: The results showed that %64.7 people had not been vaccinated. The number of hospitalized unvaccinated people was about 1.8 times the number of vaccinated people. There was no significant difference between the number of hospitalized men and women according to the vaccination status (P=.38), although there was a significant difference in the age of people (P=.001). The frequency of diabetes was higher in the vaccinated population. There was no significant difference between the number of hospitalized men and women in terms of the number of doses received (p=0.23). Also, the mortality rate in non-vaccinated people was significantly higher and this difference was significant (P=0.017).
Conclusion: Vaccination reduces mortality and hospitalization rates, so encouraging this and proper planning to prepare vaccines in similar critical situations is recommended.
Microbiology
vajiheh gharzi; sahar kalate; rahim akrami; Mohammad Shurideh yazdi; Maryam Latifnia; Mojtaba Fattahi Abdizadeh
Volume 24, Issue 6 , March and April 2018, , Pages 131-137
Abstract
Evaluation of immune response to HBV vaccine in the staff and students of Sabzevar University of Medical Sciences (2014-15) Background:Hepatitis B is a bloodborne infections and it is predicted that about two billion people in the world have been exposed to the hepatitis B virus. Because of occupational ...
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Evaluation of immune response to HBV vaccine in the staff and students of Sabzevar University of Medical Sciences (2014-15) Background:Hepatitis B is a bloodborne infections and it is predicted that about two billion people in the world have been exposed to the hepatitis B virus. Because of occupational reasons, medical students and staffs are more susceptible to expose to this disease than other members of society. Materials and Methods:This study is a descriptive-analytic study and 238 staffs and students of Sabzevar University of Medical Sciences were randomly selected and sampled. Then, the antibody titer of surface anti-protein of hepatitis B virus (HBs- Ab) was measured using ELISA method and the results were analyzed using the software Stata 12 after recording the demographic results and information. Results:Out of 238, 156 persons were female ( 65.5%) and 82 persons ( 34.5%) were male. 66% of individuals had antibody higher than 10 mu/ml and 37.4 % of individuals showed the appropriate answers higher than 100 u/ml. The relationship between job, sex and marital status with the immune response was significant. 100% of people who received full dose along with the booster vaccine were immune. Over time, the percentage of immune people has been decreased. Conclusion:Considering the reduction of response to vaccines over time and healthcare personnel being at risk, it is recommended that antibody titer was periodically examined in these individuals in 5 to 10 years to administer a booster dose in the case of a decrease in antibody titers.