immunology & Biochemistry
Nafise Annabestani; Hamid Mollania; Nasrin Mollania
Abstract
Introduction: Herbal medicine, which bears fewer adverse effects than chemical medications, is becoming more popular for the treatment of diabetes.Materials and Methods: After measuring the antioxidant properties, the inhibition pattern between the extracts and the pancreatic α-amylase enzyme was ...
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Introduction: Herbal medicine, which bears fewer adverse effects than chemical medications, is becoming more popular for the treatment of diabetes.Materials and Methods: After measuring the antioxidant properties, the inhibition pattern between the extracts and the pancreatic α-amylase enzyme was determined. Diabetic mice were treated with herbal extracts and acarbose. The blood biochemical factors were then measured. The best extract examined the synthesis of silver nanoparticles (Ag-NPs).Results: The extracts of saffron and chamomile petals showed an inhibitory effect on the α-amylase enzyme with a competitive and mixed pattern, respectively. FBS had a significant decrease in all treatment groups, and only in the group treated with an ultrasound-assisted aqueous extract of saffron petals did insulin levels increase significantly. The ALT enzyme decreased significantly in the presence of saffron extract. The reduction of the AST factor is significant only in chamomile extract. The results showed that for optimal synthesis of silver nanoparticles, values of temperature, pH, time, and silver nitrate salt concentration were 55°C, pH = 10, 4 hours, and 1.2 mM, respectively.Conclusion: The plant extracts studies can efficiently lower the blood sugar levels, increase insulin production, and regulate liver enzymes in the blood. As a result, they have a good impact on diabetes treatment. These extracts outperform the chemical medication acarbose in terms of efficacy and have no negative effects on the liver. The saffron extract demonstrates the ability to synthesize Ag-NP, which is frequently employed in biomedical applications.
Psychology
maryam Motakeffar; sheyda sodagar; maryam bahrami; najme rahimy
Volume 29, Issue 6 , January and February 2023, , Pages 822-832
Abstract
Introduction: According to the world health organization the prevalence of type 2 diabetes in our country and world will increase sharply by 2030. Improving glycemic control delays the onset and progression of diabetes complications.The purpose of this study was The effectiveness of mindfulness-based ...
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Introduction: According to the world health organization the prevalence of type 2 diabetes in our country and world will increase sharply by 2030. Improving glycemic control delays the onset and progression of diabetes complications.The purpose of this study was The effectiveness of mindfulness-based cognitive therapy and emotion-oriented therapy on glycemic control in type 2 diabetic patients.
Materials and Methods: This experimental study was a post-test pre-test by control group. The statistical population of all people with type 2 diabetes who referred to Sabzevar Diabetes Clinic in 1398. 45 were randomly placed in three groups (mindfulness-based cognitive therapy, emotion-oriented therapy and control). Patients' blood glucose was measured using a fasting blood glucose. SPSS24 software and descriptive and analytical statistics (covariance) were used to analyze the data.
Results: The analysis showed that mindfulness-based cognitive therapy had a positive and significant effect on glycemic control (P <0.05). Emotion-oriented therapy had a positive and significant effect on glycemic control (P <0.05). Both training methods mindfulness-based cognitive therapy and emotion-oriented therapy, there is no significant difference in post-test scores (P > 0.05).
Conclusion: Considering the significant effect of methods mindfulness-based cognitive therapy and emotion-oriented therapy on glycemic control in type 2 diabetic patients, it is suggested to use these two methods to improving glycemic control in type 2 diabetic patients.
Psychology
mahdi motakeffar; Abolfazl Bakhshi Pour; Mehdi Ghasemi Motlagh
Volume 29, Issue 4 , September and October 2022, , Pages 563-575
Abstract
Introduction: The aim of this study was to compare the effectiveness of mindfulness-based cognitive therapy and emotion-oriented therapy on psychological cohesion in type 2 diabetic patients.
Materials and Methods: The present study was applied in terms of purpose, with pre-test-post-test design, which ...
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Introduction: The aim of this study was to compare the effectiveness of mindfulness-based cognitive therapy and emotion-oriented therapy on psychological cohesion in type 2 diabetic patients.
Materials and Methods: The present study was applied in terms of purpose, with pre-test-post-test design, which used a quasi-experimental research design. The statistical population of the study included all people with type 2 diabetes who referred to Sabzevar Diabetes Clinic in 1398. From the mentioned statistical population, 45 people were selected by convenience sampling and randomly divided into 3 groups of 15 people (2 experimental groups and one control group). Antonovski (2006) answered the questionnaire of feeling psychological cohesion. In this study, descriptive data analysis was used to describe the collected data and the data were analyzed using SPSS statistical software.
Results: The results showed that mindfulness-based cognitive therapy and emotion-oriented therapy are effective on mental cohesion in type 2 diabetic patients and there was no significant difference in their effectiveness
Conclusion: Cognitive therapies based on mindfulness and emotion-oriented therapy can be used to moderate the psychological problems of diabetic patients.
Ali Heidarianpour; Maryam Keshvari
Volume 23, Issue 6 , January and February 2017, , Pages 916-925
Abstract
Background: Several studies have suggested the role of inflammatory factors in the development and progression of complications of diabetes. Among the inflammatory biomarkers CRP, has the most rapid reaction and subside the normal level following a successful treatment. Sectional and longitudinal studies ...
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Background: Several studies have suggested the role of inflammatory factors in the development and progression of complications of diabetes. Among the inflammatory biomarkers CRP, has the most rapid reaction and subside the normal level following a successful treatment. Sectional and longitudinal studies have confirmed the anti-inflammatory effects of exercise and its effects on various inflammatory and pre inflammatory cytokine mentioned. The purpose of this study was to compare three different ways of training on CRP levels in type 2 diabetic patients after a ten -week training is designed.
Methods: 52 patients with type 2 diabetes (65-40 years) were randomly divided into four groups: aerobic training, resistance, combined (aerobic and resistance) and control groups and each group consisted of 13 subjects. Exercise 3 times a week for 60 minutes each session lasted for 10 weeks.The high-sensitivity CRP (hs-CRP) at baseline and at the end of the study were measured by ELISA. The data analysis was done by SPSS20 and p<0.05 considered as significance level.
Results: aerobic and combined exercise significantly subsides hs–CRP level in type II diabetes patients, this decrease was more significant pronounced in combined exercise and resistance exercise has not significantly effect on hs–CRP level
Conclusion: According to the findings aerobic exercise training is particularly suitable compound to prevent inflammatory biomarkers such as CRP elevation in patients with type 2 diabetes. Therefore more studies in future maybe useful to prevent diabetic complications.
Seyyed Amir Hossein Zehni Moghaddam; Maryam Javadi; Foad AliMoradi; Asghar Mohammadpour Asl
Volume 23, Issue 1 , May and June 2016, , Pages 103-109
Abstract
Background and purpose: Diabetes is a global problem and one of the main reasons for debility and mortality in present-day societies. Some studies have indicated that Sleep Durationand blood sugar levels in diabetics are correlated, but this has not been confirmed in other research. Therefore, this study ...
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Background and purpose: Diabetes is a global problem and one of the main reasons for debility and mortality in present-day societies. Some studies have indicated that Sleep Durationand blood sugar levels in diabetics are correlated, but this has not been confirmed in other research. Therefore, this study was designed to investigate the relationship between Sleep Durationand blood sugar levels in patients with type 2 diabetes. Methods and materials: In this cross-sectional-analytical study, 244 type 2 diabetes patients referred to the Diabetes Screening Center in south Tehran were studied. After obtaining written consent from the patients, demographic information and information regarding their sleep patterns was collected, and blood samples were taken from them. The data was analyzed using the statistical analyses chi-square, independent t-test, and logistic regression. Findings: Of the 244 studied patients, 168 (68.9%) were females and 67 (31.1%) males, and their overall average age was 58.30±11.22. Study of the relationship between blood sugar level control and sleep hours controlling for demographic variables and duration of the disease showed that Sleep Durationon holidays and working days had no significant correlation with blood sugar level control in the studied patients (p>0.05). Conclusions: There was no correlation between Sleep Durationand fasting blood sugar and HbA1c in patients with type 2 diabetes. We recommend longitudinal studies be carried out in this regard.
Javad Ganjloo; Zahra Talebi; Abdolghader Asaroudi; MohammadHasan Rakhshani
Volume 22, Issue 5 , November and December 2015, , Pages 748-757
Abstract
Background & Objectives: By knowing of minimal knowledge in the diabetics and by attending to the high prevalent of effects and low quality level of life in the diabetic patient, discovering an appropriate educational method is important. The purpose of this study is comparative assessment of effect ...
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Background & Objectives: By knowing of minimal knowledge in the diabetics and by attending to the high prevalent of effects and low quality level of life in the diabetic patient, discovering an appropriate educational method is important. The purpose of this study is comparative assessment of effect of education in the OREM`s self-care model way with current method on the quality of life in diabetic type 2 patients.
Materials & Methods: This study was done on the base of randomized clinical trial method on diabetic type 2 referrals to diabetic clinics of Sabzevar city at the year of 1392. Control group were under the current education of diabet center and the case group was trained by lectures, question and response, group discussion, films and educational notes. One month after ending education, all of research units were assessed using special measure of quality of life in diabetics (ADD QOL 19). Data were analyzed by SPSS software and kai - square, mann-whitney, co-variances and logistics regression exams.
Results: In this study 50.7% (38 person) were women and 49.3 (37 person) were men. After the educational implementation, mean and SD score of QOL in the control and case groups respectively were -1.48 ± 0.719 and 1.815 ± 0.931 in the physical dimension; -1.9 ± 0.643 and 2.22 ± 0.778 in the psycho spiritual dimension; 1.48± 0.719 and 1.85 ±0/931 in social dimension. After the educational implementation, in the co-variances exam meaningful differences were seen between mean scores of QOL of two groups.
Conclusion: Unlike the current method, education plan of OREM`s model extolled the QOL of diabetics. Therefore, this method is recommended for use.
Maryam Fakhari; Leili Mahdiyeh
Volume 21, Issue 4 , September and October 2014, , Pages 629-636
Abstract
Background: Diabetes is a chronic metabolic disorder that leads to some of complications such as nerve damage that decrease proprioception sense and balance and cause cardiovascular disease. Physical activity is very important in daily schedule and improves sensitivity to insulin. The aim of this study ...
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Background: Diabetes is a chronic metabolic disorder that leads to some of complications such as nerve damage that decrease proprioception sense and balance and cause cardiovascular disease. Physical activity is very important in daily schedule and improves sensitivity to insulin. The aim of this study was to investigate the effect of of 8 weeks of selective physical activity on static balance and aerobic capacity in female patients with type 2 diabetes.
Material and Methods: This quasi-experimental study was carried out on 17 women with type 2 diabetes. The subjects selected according to investigation items and accessible sampling method. They were assigned in two experimental (age=51.4±7.3, n=8) and control (age=55.7±4.9, n=9) groups. Experimental group underwent three sessions of one hour selected exercise per week for 8 weeks. Control group did not participate in any regular exercise sessions. Static balance assess with stroke stand test and aerobic capacity measured with 6 min walk test for all subjects. Data were analyzed by SPSS 16.0 software and ANCOVA (p≤0.05) was administered.
Findings: There was no significant difference between mean of balance time between pre-test and post-test in experimental group than control group (P≤ 0.05) but mean of distance was increased significantly in experimental group than control group (P≤ 0.05).
Conclusion: A period of physical activity could increase aerobic capacity in type 2 diabetic patients and don’t have significant influence on static balance.