Physical Education
Saeed Daneshyar
Abstract
Introduction: In obesity, the serum levels of Asprosin are pathologically upregulated, this is thus considered a therapeutic target. This study aimed to explore the effect of exercise training as combined training (Aerobic+ Resistance training) along with Caffeine supplementation on the plasma levels ...
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Introduction: In obesity, the serum levels of Asprosin are pathologically upregulated, this is thus considered a therapeutic target. This study aimed to explore the effect of exercise training as combined training (Aerobic+ Resistance training) along with Caffeine supplementation on the plasma levels of Asprosin in middle-aged obese men.Materials and Methods: 38 obese men aged 35 to 50 years, with a BMI of greater than 28 participated in the research. They were stratified randomized into 4 groups. including: 1-Control-placebo (n=10), 2- Caffeine (n=10), 3- Combined training-placebo (n=9) and 4- Caffeine and combined training (n=9). The caffeine group consumed the caffeine tab 4.5 mg per kg body weight, daily, for 6 weeks. The Combined training group had concurrent aerobic and resistance training for 6 weeks (3 sessions per week). Blood samples were collected before and after the intervention, and the plasma asprosin concentration was measured by the ELISA method.Results: By the effect of the Combined training, the Asprosin level was reduced (p=0/01). Taking Caffeine alone did not significantly reduce Asprosin (p=0/19). The Asprosin declined in the group that had both Combined training and Caffeine (p=0/01).Conclusion: In order to reduce the upregulated Asprosin in obese individuals known as pathologic, combined training is recommended and/so it is not necessary to take caffeine along with the training.
Physical Education
Bentol Hoda asadi; mandana gholami; Hossein Abed Natanzi; nader shakeri
Volume 27, Issue 5 , November and December 2020, , Pages 664-671
Abstract
Introduction: Irisin is one of the skeletal muscle secreted myokine that can affect the growth of cancer cells and influence the muscular tissue changes. In the present study, the effect of four weeks continuous and interval exercise training on serum and muscular levels of irisin in breast cancer bearing ...
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Introduction: Irisin is one of the skeletal muscle secreted myokine that can affect the growth of cancer cells and influence the muscular tissue changes. In the present study, the effect of four weeks continuous and interval exercise training on serum and muscular levels of irisin in breast cancer bearing mice were investigated.
Materials and Methods: The 32 female Balb/c mice assigned in four group with eight mice including: healthy control, tumor control, interval training+tumor and continuous training+tumor groups. In order to induce breast cancer, MC4-L2 cell line were used. Interval and continuous exercise training program conducted in four weeks and five sessions per week. The 48 hours after last exercise training session, blood samples and gastrocnemius muscle tissue were isolated and used for measurement of irisin levels by ELISA method. Data analyze performed by one-way analysis of variance test and Tukey post-hock test and significant considered at p≤0.05.
Results: Significant increase of irisin serum levels in continuous (p=0.002) and interval (p=0.011) training group compared to tumor control group was observed. Tumor volume significantly decreased in continuous and interval training group (p>0.05), but not significant changes in gastrocnemius muscle weight observed after continuous and interval training (p>0.05).
Conclusion: According to present study findings, the observed antitumor effects of continuous and interval training can partly attribute to increase in irisin levels and there is no significant difference between continuous and interval exercise training
Physical Education
Mojgan Zaminafshan; Amin Isanejad; Mahmoud Nikseresht; Fatemeh Izaddoust
Volume 27, Issue 2 , July and August 2020, , Pages 237-244
Abstract
Background Leptin is mainly produced in adipose tissue and plays an important role in regulating glucose metabolism. It seems that exercise training can improve glucose homeostasis and leptin level in human. Therefore, the purpose of this study was to determine the effect of aerobic interval, non-liner ...
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Background Leptin is mainly produced in adipose tissue and plays an important role in regulating glucose metabolism. It seems that exercise training can improve glucose homeostasis and leptin level in human. Therefore, the purpose of this study was to determine the effect of aerobic interval, non-liner resistance and concurrent training on the level of serum leptin and insulin resistance in overweight women. Materials and Methods In this semi-experimental study, 40 volunteers women were randomly assigned (n = 10 each) to non‐training control, aerobic interval training, non-liner resistance training, or concurrent training group. Subjects in Exercise group were on 12-week supervised exercise training program of four three per week, whereas the control group maintained a sedentary lifestyle. Insulin resistance and leptin were assessed from fasting blood samples before and after 12-week of intervention. All data were analyzed using Statistical software version 24 and the levels of statistical significance were set at P
Hossein Taheri Chadorneshin; Mohammad Esmaeel Afzalpour; Mohsen Foadodini; Hossein Abtahi
Volume 22, Issue 1 , March and April 2015, , Pages 180-188
Abstract
Background: Researches have showed that exercise trainings increase the brain-derived neurotrophic (BDNF) and glial cell-derived neurotrophic factor (GDNF) in the brain. In addition, hydrogen peroxide (H2O2) and tumor necrosis factor alpha (TNFα) increase protein content of BDNF and GDNF in vitro. However, ...
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Background: Researches have showed that exercise trainings increase the brain-derived neurotrophic (BDNF) and glial cell-derived neurotrophic factor (GDNF) in the brain. In addition, hydrogen peroxide (H2O2) and tumor necrosis factor alpha (TNFα) increase protein content of BDNF and GDNF in vitro. However, there is insufficient information about the interactive effects of high intensity exercise training, H2O2, and TNFα on neurotrophins. Hence, in the present study, we investigated the effect of high intensity intermittent training on the content of BDNF, GDNF, H2O2 and TNFα in the brain of albino wistar rats.
Materials and methods: Sixteen albino wistar rats divided into control and high intensity intermittent training groups. High intensity intermittent training has carried out for 6 weeks with 95 to 100% of maximum oxygen consumption on treadmill. BDNF, GDNF and TNFα contents have measured by sandwich ELISA method and H2O2 concentration by colorimetric method by commercial kits. Data analyzed using Student’s t-test, and p≤0.05 considered as statistically significant.
Results: High intensity intermittent training resulted in 75 and 143 percent increased in H2O2 (p
Ali Heidarianpour; Ebrahim Zarrin kalam
Volume 20, Issue 1 , March and April 2013, , Pages 34-41
Abstract
Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this ...
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Background: Many evidence showed that exercise training has beneficial effects on skin blood flow in the health and diabetic condition. On the other hand some finding showed that C-peptide has protective and therapeutic effect on vascular dysfunction-induced by diabetes. Therefore the purpose of this study is effects of resistance exercise on vascular function of C-peptide. Materials and methods: In this experimental study, Male wistar rats (220±10g, N=30) were used in two diabetic (control and trained) and one age-matched healthy control groups. After 1 week of diabetes induction, animals were submitted to resistance exercise training for 9
Weeks on ladder. To characterize cutaneous micro vascular responses by Laser Doppler
flowmetery, animals were deeply anesthetized by intraperitoneal injection of pentobarbital
sodium (50 mg/kg). For data analysis, one-way ANOVA test was used to compare the groups. Statistically significant difference between the minimum acceptable levels is p<0.05
Results: Local microinjection of c-peptide increased coetaneous blood flow in trained and control diabetic rats, however this effect in trained group is higher than control diabetic group rats. Administration of Nw-nitro-L-arginine (nitric oxide synthase inhibitor) before C-peptide reduced significantly C-peptide vascular effects in trained and control diabetic rats. Conclusions: Chronic resistance exercise potentiate C-peptide vascular function, possibly by nitric oxide pathway